Centres, groups and projects
Centres, groups and projects
With research grant income of more than £180 million per year, LSHTM is home to a large number of exciting and impactful research activities. We have a global presence with staff conducting research in more than 100 countries and we are deeply committed to working in collaboration with external partners. We are also home to three designated World Health Organization Collaborating Centres.
Featured research
Explore all Centres, groups and projects
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Adapting a complex violence prevention intervention.
SafeCare is a quality improvement model developed by the NGO PharmAccess, aimed at lower-level public and private health facilities in sub-Saharan Africa. The private sector is a major and growing source of care, but there are concerns about quality and safety, and these are insufficiently addressed by government regulation or international hospital accreditation standards. SafeCare was designed to address this gap, offering realistic setting-appropriate standards and stepwise certification, as well as access to credit for implementing improvements.
Reconstructing Africa’s demographic past. Exploring new sources, methods and technologies to uncover long-term population trends.
How does agriculture affect health? Besides its impact on diets and nutrition, changing agricultural landscapes and food systems can have major effects on the transmission of human infectious diseases. We study these interactions and welcome other LSHTM researchers and collaborators to join us in this exciting work.
Broadening the evidence base on HIV epidemiology for informing policy, strengthening the analytical capacity for HIV research, and fostering collaboration between network members.
AMBITION (High Dose AMBISOME on a Fluconazole Backbone for Cryptococcal Meningitis Induction Therapy in sub-Saharan Africa: A Randomised Controlled Non-inferiority Trial) is a four-year project funded at just under €10M by the European and Developing Countries Clinical Trials Partnership, the Swedish International Development Agency and the DFID/MRC/Wellcome Trust Joint Global Health Trials Fund. It runs from 1 January 2017 – 31 December 2020 across a consortium of five European and six African partners.
The Andhra Pradesh Children and Parent Study (APCAPS) is a large prospective, intergenerational cohort study in Southern India that began with the long-term follow-up of the Hyderabad Nutrition Trial (1987-1990). It is situated in 29 villages near the city of Hyderabad in Ranga Reddy district, Andhra Pradesh.
The Anthropological Approaches to Global Health group (AAGH) brings together a team of medical anthropologists conducting innovative research on a variety of topical challenges in global health
We provide a forum for discussion, research dissemination, and building new research collaborations between researchers within LSHTM who associate themselves with these two disciplines.
We develop perspectives on antimicrobial resistance that draw from social theories about medicines, care, technologies, infrastructures, global arrangements on health, multi-species interactions, futures and more.
Bringing together a team of social scientists from a range of disciplines, including political science, social policy, anthropology and international relations, that research critical questions in global health, contributing to the field of health policy and systems research.
The Anti-fibrinolytics Trialists Collaboration (ATC) is an international collaboration to conduct individual patient data meta-analyses of results from randomised trials of anti-fibrinolytics versus placebo.
Fresh approaches to the study of antimicrobials in society.
Inspiring innovation in AMR research through interdisciplinary and international engagements.
World-leading independent test centre for consultancy, and the evaluation and development of arthropod pest control technologies.
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A general framework for behaviour change programming, founded in the latest behavioural science and design thinking.
BHF PROTECT-TAVI is a research study examining the effect of cerebral embolic protection devices on the risk of stroke in patients undergoing Transcatheter Aortic Valve Implantation for aortic stenosis.
State-of-the-art facility to analyse and assess a variety of key medicinal drugs (notably antimalarials, antiretrovirals and antimicrobials) as formulations, in patient samples, and insecticides on fabrics.
Former England rugby players are taking part in a major study to investigate the sport's effects on brain health.
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A platform to support policymakers and researchers working on the economics of COVID-19 in Low- and Middle-Income Countries (LMICs).
The Campylobacter Resource Facility uses genome-based technologies such as next-generation sequencing, microarrays and mutants to study the pathogenesis of this microorganism.
Explaining trends and inequalities in cancer survival at regional, national and international level, including in socio-economic, racial and ethnic groups of the population.
Promoting skin & soft tissue infection care and preventing AA amyloidosis among people who inject drugs in the UK.
Improving the design and conduct of public health evaluations, and facilitating the use of robust evidence to inform policy and practice decisions.
Improving understanding of and responses to chronic conditions in low, middle and high-income country settings through research, policy and public engagement and teaching.
Strongly encourages research and collaboration fostering integration of mental health with the care of other communicable and non-communicable diseases.
We are a world-leading group of over 50 academics working on a diverse portfolio of health economics research, with work ranging from the development of innovative methods and empirical research, to policy engagement and impact.
Promoting and undertaking high quality research to develop and deepen historical understanding in the field of public health and health services policy.
Strengthening and promoting innovation, evaluation and evidence-based policy making by fostering communication and collaboration between researchers and policy makers.
Statistical and methodological expertise to strengthen research capacity in epidemiology, public health and policy.
Modelling infectious disease dynamics to improve global health.
Supporting sustainable and healthy cities, understanding and controlling infectious disease, and delivering sustainable and healthy food systems.
The CHAMNHA project investigates the effects of heatwaves and climate change on maternal and neonatal health in sub-Saharan Africa.
A journal club dedicated to researching child obesity.
Bringing a public health approach to prevention of violence in childhood and adolescence, and to improving child protection internationally.
CCSS-Z is a mixed-methods study that works with partners in Zimbabwe to support the design and intervention of a child safeguarding intervention in Catholic Primary schools. The study consists of qualitative research being conducted alongside the development of the intervention, a process evaluation, and an impact evaluation.
The Clinical Trials Unit (CTU) at the London School of Hygiene & Tropical Medicine is a world renowned centre of excellence in the design, conduct, analysis and reporting of clinical trials.
Preparing, maintaining and promoting systematic reviews for the prevention, treatment and rehabilitation of traumatic injury, including the emergency resuscitation of seriously injured and burned patients.
Group of eye health organisations from several Commonwealth countries working together to deliver an exciting, integrated, five-year programme of fellowships, research and technology which aims, over the long-term, to strengthen eye health systems and quality of eye care throughout the Commonwealth.
Research for policy reform on international disease control in Southeast Asia and beyond.
Exploring pathways to intimate partner violence prevention and developing methodology to evaluate gender transformative programmes.
Understanding how family, peer, school and community contexts affect children’s experience of violence in adolescence and early adulthood.
The COSMIC project uses system dynamic and agent-based modelling to better understand how health systems function and respond to health programmes, such as payment for performance schemes.
Driving clinical & biomedical research to improve the recognition, diagnosis and treatment of ME/CFS.
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Dagu aims to develop Ethiopian excellence in public health evaluation and improve quality and utilisation of primary and community-based health care services.
The Dagu project is working on developing Ethiopian excellence for public health evaluation: measurement, learning and evaluation of improved integrated community case management and community-based newborn care in Ethiopia.
Seeking to measure and solve the mystery of a kidney disease epidemic which is leading to the premature deaths of thousands of young people in low and middle income countries.
Research into community dialogues and participation to promote health, increase equity and amplify less-heard voices.
The Diagnostic Parasitology Laboratory is a modern well equipped laboratory located in the Department of Infectious and Tropical Diseases here at the LSHTM.
The Disease Control Priorities 3 (DCP3) UHC Country Translation is a multi-year project, designed to respond to the increasing need of low and middle-income countries for technical guidance and support in priority setting and in accelerating progress towards Universal Health Coverage.
Evaluating the impact of the Determined, Resilient, Empowered, AIDS-free, Mentored, and Safe (DREAMS) Partnership
The purpose of this project is to map the geographical distribution of resistance mutations in African Plasmodium falciparum malaria.
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The Ebola vaccine projects – EBOVAC1, EBOVAC2, EBODAC and EBOMAN – are a series of trials and associated projects which aim to assess a novel prime-boost preventive vaccine regimen against Ebola Virus Disease (EVD).
A diverse team capitalising on research opportunities offered by routinely collected data, bringing methodological rigour to provide real-world evidence for important questions regarding human health.
EMERGE is a discussion and social group for ‘career-young’ researchers and students interested in development and application of statistical methodology.
The Erythema Nodosum Leprosum International STudy (ENLIST) group is an international partnership between seven countries focused on improving the understanding and treatment of Erythema nodosum leprosum (ENL).
The Entebbe Mother and Baby Study (EMaBS) is a unique birth cohort, on-going in Africa.
The focus for the London School of Hygiene & Tropical Medicine’s work on water, sanitation, hygiene and health.
The Environmental Health Group (EHG) is the focus for the School’s work on WASH (Water, sanitation and hygiene) and health.
This project investigates how Brazil’s national programme for improving primary care access and quality has affected inequalities in the financing and delivery of primary care.
Effect of Remote Ischaemic Conditioning on clinical outcomes in ST-segment elevation myocardial infarction patients undergoing Primary Percutaneous Coronary Intervention (ERIC-PPCI).
Research question: how effective and cost-effective is emergency surgery for patients with common acute conditions presenting as emergency admissions to NHS hospitals.
ZIKAlliance is a multinational and multi-disciplinary research consortium comprised of 53 partners worldwide and coordinated by Inserm, the French National Institute of Health and Medical Research.
Developing disease, behavioural and economic models to assess whether and how to intervene to improve global health.
This interdisciplinary group applies the theoretical framework of evolutionary biology to human demographic behaviour.
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Working closely together with government policymakers and food system stakeholders, including farmers, retailers and consumers, the FACE-Africa project aims to jointly generate evidence to inform climate change adaptation strategies in food systems.
FIEBRE aims to reveal leading causes of fever in sub-Saharan Africa and southeast Asia. What are the main infections causing fever in children and adults, and how should they be treated?
The Forms of Care project ethnographically examines practices of ‘not doing’ in UK palliative care practice, and how these may nevertheless be an active and valuable form of care.
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An inter-disciplinary research group with expertise on violence against women, violence against children, violence against men, violence among same-sex people, migration, labour exploitation and human trafficking. A WHO Collaborating Centre since 2019.
Investigating genetic mechanisms underlying attractiveness of humans to mosquitoes.
The Global Asthma Network was established in 2012 to improve asthma care globally, with a focus on low- and middle-income countries, through enhanced surveillance, research collaboration, capacity building and access to quality-assured essential medicines.
Eye Health is essential to Child Health. We work to ensure that all children are getting access to eye health services to ensure they have the best vision possible.
An independent group of influential experts with a commitment to tackling global challenges in food and nutrition security.
Supporting government and partners in strengthening health systems for better mental health of Syrian refugees and host communities in Lebanon.
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Developing surveillance and research in Eastern Ethiopia to improve maternal and child health.
Former football players are taking part in a major study to investigate effects of the sport on brain health.
We have a dynamic group of over 50 health economists working on a diverse portfolio, ranging across methods development, empirical research and policy impact. Over the past 50 years we have developed strong national and international partnerships. LSHTM economists have a wealth of experience in advising UK and other national governments, international agencies and organisations.
We are a group of over 50 staff with internationally recognised expertise in a wide range of disciplines including health economics, policy analysis, public health, epidemiology and social science.
High-impact research on health financing to improving health service delivery and equity in low and middle-income countries
Promoting research, education and knowledge translation to improve health and health equity in populations affected by humanitarian crises.
The HPP Debated blog offers news, comment and analysis on the latest research published in Health Policy and Planning.
The Health Reform Evaluation Programme (HREP) is a recently completed programme of research to evaluate the English NHS reforms set out in the Department of Health publication Health Reform in England: update and next steps.
Presenting the health systems research being undertaken by the London School of Hygiene & Tropical Medicine as well as listing relevant teaching programmes, resources and events.
The overarching purpose of this award is to provide an intellectual and policy history of ‘health systems’ thinking.
Strengthening health systems through evidence-based and interdisciplinary research
The Health Economics MOdelling of Blood Donation study (the HEMO study) aims to determine the cost-effectiveness of the different ways of maintaining the future supply of blood to the NHS.
The UNITAID/PSI HIV Self-Testing Africa (STAR) Project is a four-year initiative to catalyse the market for HIV self-testing.
Evaluating the impact of Peer Advocates on the use of health care for adults in London who are homeless.
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We are focused on improving outcomes for people with kidney and cardiovascular disease in the UK.
IDEAS aims to improve the health and survival of mothers and babies through generating evidence to inform policy and practice. Working in Ethiopia, North-Eastern Nigeria and the state of Uttar Pradesh in India, IDEAS uses measurement, learning and evaluation to find out what works, why and how in maternal and newborn health programmes.
IMPRESS investigates whether enhanced management practices can improve newborn survival and the quality of clinical care in hospitals in Malawi.
Investigating quality improvement in general practices – what do they do and how do they do it? A survey of GPs and Practice Managers.
Academic research group describing and explaining regional and socio-demographic differences in cancer outcomes, to influence policy and improve outcomes for all.
Developing tools, techniques and evidence about disability, leading to scalable interventions for public health and development.
The International Centre for Eye Health is a research and education group working to improve eye health and eliminate avoidable visual impairment and blindness, with a focus on low-income populations.
Facilitating the development, evaluation and implementation of accessible, quality assured in-vitro diagnostics for global health, through information sharing and advocacy.
This mixed-method study combines a four-wave longitudinal quantitative design with qualitative interviews to explore the predictors of intimate partner violence in Mwanza, Tanzania.
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Partnership to support the control and elimination of visceral leishmaniasis in six countries, three in Asia (India, Nepal and Bangladesh) and three in Africa (Ethiopia, Sudan and South Sudan).
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LAMP4Yaws is a multi-country EDCTP-funded project, assessing the real-life accuracy of a new diagnostic test in yaws-endemic areas of Ghana, Côte d’Ivoire and Cameroon, to support WHO’s yaws eradication strategy.
LASER combines expertise in the fields of spatial statistics and GIS technology, quantitative epidemiology and operational research to build the evidence-base around diseases of poverty and the communities they affect.
Promoting best practice in learning and teaching through educational research (to join, contact Anna Foss).
Exploring the potential of communities and social norms to prevent violence against and exploitation of children and adolescents.
Investigating the best use of liver transplantation to treat patient’s with hepatocellular carcinoma (HCC).
Our research group is focussed on the discovery, evaluation and implementation of novel interventions for the control vector borne diseases, from basic scientific studies in the laboratory understanding vector-host-pathogen interactions, to large scale field trials.
Facilitating interdisciplinary research and training to tackle complex problems in international development. We bring together social and natural scientists from across the University of London's Bloomsbury Colleges: Birkbeck, UCL Institute of Education, London School of Hygiene & Tropical Medicine, Royal Veterinary College, and SOAS.
Collaborating with leading scientists from Germany, UK, and further afield to conduct, and promote discussion around, cutting-edge research on global health issues including migration, gender, health equity and health systems.
With one of the largest groupings of Neglected Tropical Diseases researchers, the London School of Hygiene and Tropical Medicine is internationally recognised as a leading centre for NTD research. The NTD Network is designed to make it easier for you to find and access that expertise.
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Computable General Equilibrium (CGE) modelling of health, health policy or broader policy with implications for health
Violence, mental health, biological changes to the immune system and HIV risk: a three-year mixed-method, longitudinal study with 1000 women in Nairobi, Kenya
The Malaria Reference Laboratory (MRL) provides laboratory reference and diagnostic parasitology of malaria, and surveillance data on all imported malaria reported in the UK.
Malaria Zero is an alliance of partners with one bold goal: to eliminate malaria from the island of Hispaniola by 2020.
Malawi Epidemiology and Intervention Research Unit (MEIRU), formerly known as Karonga Prevention Study, has over the last 30 years made major contributions to the understanding and control of mycobacterial disease, HIV and other infectious diseases.
The Maternal and Newborn Health Group carries out research to contribute to the international debate and key policy, measurement and evaluation issues related to the health of young children and their mothers.
We conduct multidisciplinary research on the role of the private and public health sectors in delivering maternal and reproductive health care.
To better understand the mortality burden of antimicrobial resistance in low and middle income countries in sub-Saharan Africa.
Staff and research degree students in Department of Global Health and Development conducting interdisciplinary social science research to improve the health, wellbeing and voice of people affected by humanitarian crises.
The Measurement and Surveillance of HIV Epidemics Consortium (MeSH) develops, tests and implements innovative and efficient methods for routine HIV measurement and surveillance among adults and children.
Our research aims to develop new guidance for systematic reviewers when making a decision about whether or not to use a meta-analytical approach to the synthesis of quantitative evidence, with a particular emphasis on the synthesis of studies of complex interventions.
A research collaboration addressing pressing issues facing health systems globally and at a national level in South Africa – the impacts of and response to migration and its intersection with gender.
Welcome! This site exists to support researchers from the social and medical sciences with the analysis of incomplete datasets, and as a focus of statistical research in this area.
We are a group of mathematical modellers and health economists based at LSHTM and Public Health England who conduct applied epidemiological and economic research to inform public health decisions about vaccination.
MONKEYBAR is a project seeking to identify risk factors and control strategies for Plasmodium knowlesi, a zoonotic malaria carried by macaques.
The Nutrition Theme of MRC Unit, The Gambia is closely linked to the MRC International Nutrition Group (ING) at the London School of Hygiene and Tropical Medicine (LSHTM) and to MRC Human Nutrition Research in Cambridge.
Collaborating with international research partners to improve health in low and middle-income countries.
MITU’s mission is to contribute to improving health through the development and evaluation of interventions against HIV and other health problems.
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Revealing the changing sexual attitudes and behaviour of the British population, Natsal is one of the largest scientific studies of sexual health and lifestyles in the world.
The aim of this HPRU is to enable health decisions makers to have the knowledge, foresight and tools to mitigate, adapt to and benefit from environmental change.
The NIHR Public Health PRU (PH-PRU) conducts public health research with a social determinants focus.
Addressing the major nutrition and food-related problems that affect human development and well-being, at national and global levels.
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There is a mystery epidemic of Chronic kidney disease of unknown cause (CKDu) affecting agricultural and non-agricultural communities in Mesoamerica. This disease has reduced the life expectancy of thousands and caused the deaths of tens of thousands young males and females.
The OPT-SMC project supports national malaria control programmes in West and Central Africa to conduct implementation research on Seasonal Malaria Chemoprevention by providing grants and technical assistance, and facilitates sharing of information and expertise between countries. The project is a partnership between the national malaria control programmes in 13 countries.
ORCA aims to improve the quality of health data in Ethiopia by supporting analysts at the Ministry of Health, Ethiopia.
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The Pathfinder Initiative, funded by the Wellcome Trust with support from the Oak Foundation, supports rapid progress towards a healthy, zero-carbon society.
Advancing healthcare knowledge through patient and public involvement.
Patients’ views are essential to achieving high-quality healthcare. Our PROMs research is helping to improve patient care by evaluating the performance of health care providers and guiding NHS reforms.
PENDA is consortium lead by the International Centre for Evidence in Disability, it is focused on creating evidence to achieve long-term improved wellbeing and inclusion of people with disabilities in Low and Middle Income Country's (LMICs), through building knowledge, people and tools.
Investigating the effectiveness of different treatments for Type 2 Diabetes Mellitus.
Pilot RCT of a complex violence prevention intervention.
This project is funded by a Wellcome Trust Medical Humanities New Investigator Award, awarded to Dr Alex Mold in 2013 and is based in the Centre for History in Public Health at the LSHTM.
The Policy Innovation and Evaluation Research Unit (PIRU) brings together leading health and social care expertise to improve evidence-based policy-making and its implementation across the National Health Service, social care and public health.
Researching health at the interface of economics and politics
A major study in South Africa and Zambia to test a new approach to the prevention and control of HIV in Africa.
The Population Studies Group (PSG) is engaged in the measurement and explanation of population trends and in the evaluation of attempts to modify them.
The Population Studies Group (PSG) is engaged in the measurement and explanation of population trends and in the evaluation of attempts to modify them.
How people respond to vaccines, and how well they work, varies between populations. POPVAC’s goal is to understand these differences in order to identify strategies of improving vaccine effectiveness.
The Praziquantel in Preschoolers trial (PIP) aims to find the right treatment dose of praziquantel for preschool children living with intestinal schistosomiasis in Uganda.
Training teachers on emotional self-regulation and positive discipline to prevent and reduce violence against children in schools in Nyarugusu refugee camp.
A randomised double-blind controlled phase III study to compare the efficacy and safety of intravenous ferric carboxymaltose with placebo in patients with anaemia undergoing major open abdominal surgery.
Studying private healthcare provision – how it works, how to improve it and where it fits in universal health care
Developing an evidence base and platform for action around how violence in childhood and adolescence affects child labour, participation in skills programmes and employment outcomes in Uganda.
The Policy Research Unit in Commissioning and the Healthcare System (PRUComm) provides evidence to the Department of Health to inform the development of policy in the National Health Service. We focus on maximising outcomes for patients.
The Public Health Research Consortium (PHRC) brings together senior researchers from 11 UK institutions in a new integrated programme of research, with the aim of strengthening the evidence base for interventions to improve health, with a strong emphasis on tackling socioeconomic inequalities in health.
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Research capacity strengthening and knowledge generation to support preparedness and response to humanitarian crises and epidemics.
Renal protection against ischaemia-reperfusion in transplantation: a randomised double blind placebo-controlled trial of 400 living-donor renal transplant patients.
The Resilient and Responsive Health Systems (RESYST) is an international research consortium that aims to enhance the resilience and responsiveness of health systems to promote health and health equity and reduce poverty.
Multicentre prospective randomised open controlled trial aiming to evaluate the efficacy and safety of percutaneous coronary intervention compared to optimal medical therapy alone for ischaemic left ventricular dysfunction.
Exploring infidelity, romantic jealousy and intimate partner violence.
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A randomised controlled trial of an intervention delivered by mobile phone messaging to reduce sexually transmitted infections (STI) by increasing sexual health precaution behaviours in young people.
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The Sustainable Evaluation through Analysis of Routinely Collected HIV data (SEARCH) is a collaboration between the London School of Hygiene & Tropical Medicine and the Ministries of Health in Malawi, Tanzania and Zambia, and is funded by the Bill & Melinda Gates Foundation.
Strengthening health service delivery and quality of care through high-impact, interdisciplinary research.
SHARE contributes to achieving universal access to effective, sustainable and equitable sanitation and hygiene by generating evidence to improve policy and practice worldwide.
Working in partnership across five institutions, we conduct multi-disciplinary research in Ghana and Ethiopia to improve experiences of severe and stigmatising neglected tropical diseases of the skin.
We are a group of multidisciplinary academics working on a diverse portfolio of epidemiology research, largely focused on skin disease.
The Social and Mathematical Epidemiology (SaME) group is a dynamic group of about 40 researchers working on a variety of areas in public health.
The SEARN is a platform to facilitate research collaboration. It provides a forum to support the communication and dissemination of research findings, highlight research areas and a network connecting people in LSHTM and collaborators outside with an interest in South East Asia.
Funded by the Bill & Melinda Gates Foundation and facilitated by the London School of Hygiene and Tropical Medicine, SPEAK India brings together researchers and technical experts alike, with an aim to develop a consensus on the additional knowledge required to ensure VL transmission is successfully interrupted and elimination is sustained.
Our research aims to strengthen evidence and understanding for better decision-making on the social and environmental factors that determine public health.
SPRING for MDG’s (Sustainable Program Incorporating Nutrition and Games) is a seven year research programme funded by the Wellcome Trust that brings together researchers from the UK, India and Pakistan.
SSACAB brings together African and Northern academic and research institutions to develop and improve biostatistical skills among researchers.
Cross-faculty and cross-disciplinary group to promote STI research conducted at LSHTM
STRIVE is a research consortium investigating the social norms and inequalities that drive HIV.
200 million people still live in trachoma-endemic regions and are at risk of becoming blind despite concerted international effort to tackle the disease. With the clock ticking towards the 2020 elimination goal, novel strategies are urgently needed to accelerate and strengthen the SAFE strategy.
Recognising that people with psychosocial disabilities are best positioned to define their own needs, SUCCEED is co-producing the design and evaluation of community-based interventions for people with psychosis in Africa.
We are assessing how UK funding to Support the National Malaria Programme in Nigeria is affecting change.
This research project aims to improve surgical services for women with urinary incontinence in England.
SHEFS is a programme aiming to provide policy makers with novel, interdisciplinary evidence to define future food systems policies that deliver nutritious and healthy foods in an environmentally sustainable and socially equitable manner.
We conduct formative research into the health and wellbeing needs and priorities of host communities in which around 30 Anglo-American mines are situated, in eight countries.
A five-year programme of research and evaluation funded by the UK Department of International Development (DFID). SWiFT assesses, evaluates and informs the International Labour Organisation’s DFID-funded “Work in Freedom” multi-country intervention to minimise women’s vulnerability to labour trafficking in South Asia and the Middle East.
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Improving public health research in Tanzania through joint research and capacity-building, including through better communications and networking for LSHTM staff, students, and alumni in Tanzania.
Providing a focus for global research expertise in tuberculosis epidemiology, immunology, diagnosis and treatment.
The TB Modelling Group at LSHTM uses mathematical and statistical models to better understand the natural history and epidemiology of tuberculosis (TB) and to improve the contribution of TB modelling to policy decisions and implementation.
Boosting big data expertise and applying genomic technologies across LSHTM.
Co-Create is a project designed to reduce obesity and its co-morbidities by working with adolescents, to create, inform and disseminate obesity-preventive, evidence-based policies, using a complex systems approach.
The DE-grading Epidemiology (DEEP) Network has been formed to encourage open debate about the use of algorithms to assess epidemiological studies, and maintain contacts between those of us who are working on these issues. It will pursue strategies to improve our ability to methodically and accurately integrate and interpret epidemiologic evidence.
The value and unexpected by-product of a community engagement strategy aimed at addressing the immunisation gap in north-west Ethiopia.
The Global Vector Hub is an open access, interactive resource. It has the capacity to transform vector research and vector control programmes, and to revolutionise our preparedness and ability to respond quickly and effectively to vector-borne disease outbreaks, around the world.
M. tuberculosis is a leading cause of meningitis in people living with HIV. Currently, over 50% of cases die and many survivors are left disabled. Finding better diagnostics and optimised treatments is a priority.
This collaborative research project, funded by the National Institute for Health Research (NIHR), Health Services and Delivery Research Programme, examines the experiences of young people with sickle cell as they transition to adulthood and move from using child to adult services.
THRiVE’s mission is to empower African Institutions to become research engines for health innovations and evidence-based healthcare practices and policies.
Tight K is a study investigating whether maintaining serum potassium levels at ≥3.6 mEq/L is non-inferior to maintaining at ≥4.5 mEq/L on the occurrence of new onset atrial fibrillation dysrhythmia post-surgery in patients undergoing isolated CABG surgery
This website is created to facilitate an informal network for researchers using the Test-Negative-Design (TND) for studying the causes of COVID-19 infection. We will create a repository of papers about the use of the TND, and for questionnaires for use in TND studies of the causes of COVID-19.
The TREATS project (Tuberculosis Reduction through Expanded Antiretroviral Treatment and Screening for active TB) will measure the impact of a combined TB and HIV intervention – of population level active case-finding for TB, combined with universal testing and treatment for HIV -- on TB incidence, prevalence and incidence of infection when delivered to the entire population of 14 urban, high-prevalence communities in South Africa and Zambia.
We conduct studies on the epidemiology and control of major public health problems of developing countries, with a major focus on HIV, tuberculosis, malaria and neglected tropical disease, and a special emphasis on intervention studies.
The effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage: an international, randomised, double-blind, placebo-controlled trial.
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A specialist team ready to respond to disease outbreaks around the world before they develop into health emergencies. The team also conducts rigorous operational research to improve epidemic preparedness.
We explore how formal and informal structures and practices in health systems interact with the socio-political context to undermine accountability and encourage corruption in Malawi and Nigeria, and ask how to overcome them.
We use Shigella infection to discover new roles for the cytoskeleton in host defence, and use zebrafish to study the cell biology of infection in vivo.
Investigating whether dogs can be trained to identify unique odours associated with coronavirus infection
Understanding and preventing sexual and other forms of violence against children in Zanzibar.
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Bringing together research from vaccine design and immunological characterisation through clinical trials to epidemiological evaluation, safety, economic, social science and policy analysis.
Using model-based drug development methods (PK/PD) to accelerate vaccine dose decision making.
Our overall aim is to support decision-making about the choice or modification of vaccination schedules at international, regional and country levels.
The purpose of VITALITY trial is to establish whether supplementation with vitamin D and calcium optimises musculoskeletal health among peripubertal children with HIV in Zimbabwe and Zambia.
This is the first RCT to investigate this intervention to improve bone health in HIV children.
PI: Prof Rashida Ferrand (LSHTM/ Biomedical Research & Training Institute (BRTI), Harare)
Funder: EDCTP
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We aim to recruit and train the best young clinical and non-clinical scientists with an interest in global health research, to provide them with the support, training and academic environment they need to develop into independent researchers, and to facilitate their academic and clinical career progression.
The WOMAN trial, coordinated by the London School of Hygiene & Tropical Medicine (LSHTM) Clinical Trials Unit (CTU) is an international clinical trial of the effect of tranexamic acid on death, hysterectomy and other maternal outcomes, in women with PPH.14.
The World AsthmaPhenotypes Study (WASP) aims to better understand and characterise different sub-types (phenotypes) of asthma.
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A multinational and multidisciplinary consortium implementing critical research on the existing Zika virus outbreak whilst preparing a sustainable response capacity for future emerging epidemics in Latin America.
A research group committed to safeguarding and improving health across the life-course