Centres, groups and projects
Centres, groups and projects
With research grant income of more than £180 million per year, LSHTM is home to a large number of exciting and impactful research activities. We have a global presence with staff conducting research in more than 100 countries and we are deeply committed to working in collaboration with external partners. We are also home to four designated World Health Organization Collaborating Centres.
Featured research
Explore all Centres, groups and projects
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Adapting a complex violence prevention intervention.
Reconstructing Africa’s demographic past. Exploring new sources, methods and technologies to uncover long-term population trends.
The Afya Consortium for research on public health threats in populations affected by crises: a multi-disciplinary, collaborative research programme
How does agriculture affect health? Besides its impact on diets and nutrition, changing agricultural landscapes and food systems can have major effects on the transmission of human infectious diseases. We study these interactions and welcome other LSHTM researchers and collaborators to join us in this exciting work.
Generating data and evidence on real-world applications of artificial intelligence (AI) in addressing healthcare challenges worldwide.
Broadening the evidence base on HIV epidemiology for informing policy, strengthening the analytical capacity for HIV research, and fostering collaboration between network members.
The AMRnet project aims to develop a data-visualisation dashboard that makes genome-derived antimicrobial resistance (AMR) data accessible to a wide range of stakeholders including policy makers.
The Anthropological Approaches to Global Health group (AAGH) brings together a team of medical anthropologists conducting innovative research on a variety of topical challenges in global health
We provide a forum for discussion, research dissemination, and building new research collaborations between researchers within LSHTM who associate themselves with this discipline.
We develop perspectives on antimicrobial resistance that draw from social theories about medicines, care, technologies, infrastructures, global arrangements on health, multi-species interactions, futures and more.
The Anti-fibrinolytics Trialists Collaboration (ATC) is an international collaboration to conduct individual patient data meta-analyses of results from randomised trials of anti-fibrinolytics versus placebo.
Fresh approaches to the study of antimicrobials in society.
Inspiring innovation in AMR research through interdisciplinary and international engagements.
The Andhra Pradesh Children and Parents’ Study (APCAPS) is a prospective inter-generational cohort that has been incrementally built through long-term follow-up of a nutrition trial (1987-90) in Telangana, south India.
Ayurveda for Promoting Recovery In Long COVID (APRIL) is a randomised trial examining whether a traditional Indian herbal medicine benefits adults suffering with long-term symptoms of COVID-19 (Long COVID) in the UK.
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A globally representative group of researchers accelerating the development of medical countermeasures against priority bacterial pathogens Vibrio cholerae, Yersinia pestis, Shigella spp., non-typhoidal Salmonella serovars Enteritidis and Typhimurium, and Klebsiella pneumoniae.
A general framework for behaviour change programming, founded in the latest behavioural science and design thinking.
BHF PROTECT-TAVI is a research study examining the effect of cerebral embolic protection devices on the risk of stroke in patients undergoing Transcatheter Aortic Valve Implantation for aortic stenosis.
State-of-the-art facility to analyse and assess a variety of key medicinal drugs (notably antimalarials, antiretrovirals and antimicrobials) as formulations, in patient samples, and insecticides on fabrics.
Former England rugby players are taking part in a major study to investigate the sport's effects on brain health.
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Explaining trends and inequalities in cancer survival at regional, national and international level, including in socio-economic, racial and ethnic groups of the population.
Looking into existing data from ongoing cohort to explore how social norms and attitudes towards violent experiences affect the relationships between violence and various health, education, labour and biomarker outcomes.
Promoting skin & soft tissue infection care and preventing AA amyloidosis among people who inject drugs in the UK.
The Catch-up Screen project offers Human Papillomavirus (HPV) urine testing as a tool for cervical screening among women aged 60-79 who ceased from the NHS Cervical Screening Programme without a primary HPV test.
The Causes And MEchanisms foR non-atopic Asthma in children (CAMERA) study will investigate the causes of non-atopic asthma and also investigate three possible mechanisms of non-atopic asthma in four settings.
The Centre aims to bring together between LSHTM researchers focused on: long-term care, its interface with health systems and the impact of megatrends like climate change and migration.
Bringing together data and statistical science expertise from across LSHTM to generate new opportunities for research, training and knowledge exchange into policy and practice.
Bringing together interdisciplinary research and expertise from across the world to improve learning and prepare for future pandemics and disease outbreaks.
Improving the design and conduct of public health evaluations, and facilitating the use of robust evidence to inform policy and practice decisions.
Improving understanding of and responses to chronic conditions in low, middle and high-income country settings through research, policy and public engagement and teaching.
Strongly encourages research and collaboration fostering integration of mental health with the care of other communicable and non-communicable diseases.
Promoting and undertaking high quality research to develop and deepen historical understanding in the field of public health and health services policy.
Strengthening and promoting innovation, evaluation and evidence-based policy making by fostering communication and collaboration between researchers and policy makers.
Modelling infectious disease dynamics to improve global health.
Supporting sustainable and healthy cities, understanding and controlling infectious disease, and delivering sustainable and healthy food systems.
The CHAMNHA project investigates the effects of heatwaves and climate change on maternal and neonatal health in sub-Saharan Africa.
Stakeholder engagement, chikungunya burden estimation, and vaccine impact modelling.
Bringing a public health approach to prevention of violence in childhood and adolescence, and to improving child protection internationally.
CCSS-Z is a mixed-methods study that works with partners in Zimbabwe to support the design and intervention of a child safeguarding intervention in Catholic Primary schools. The study consists of qualitative research being conducted alongside the development of the intervention, a process evaluation, and an impact evaluation.
Exploring the implementation of the Children and Young People’s Mental Health Green Paper Programme.
This project explores the intersection between Children, Cities and Climate Change and has three primary aims:
- To model the potential co-benefits to child and adolescent health that could arise from changes to the construction and design of cities
- To understand young people’s views about their cities and
- To collate and share through a diverse range of channels our research findings and young peoples’ visions for healthy cities of the future.
CHIP-BCIS3 (Controlled trial of High-risk coronary Intervention with Percutaneous left ventricular unloading) is a research study investigating whether a heart pump improves the safety and effectiveness of high-risk coronary artery stenting procedures.
The LSHTM Clinical Trials Unit is accredited by the UK Clinical Research Collaboration. We conduct high-quality, high-impact trials in the UK and internationally.
The CDRG conducts research on the effects of unhealthy commodities, and on the tactics used by their manufacturers. It also researches the misinformation strategies used by harmful industries.
Group of eye health organisations from several Commonwealth countries working together to deliver an exciting, integrated, five-year programme of fellowships, research and technology which aims, over the long-term, to strengthen eye health systems and quality of eye care throughout the Commonwealth.
Research for policy reform on international disease control in Southeast Asia and beyond.
Exploring pathways to intimate partner violence prevention and developing methodology to evaluate gender transformative programmes.
Understanding how family, peer, school and community contexts affect children’s experience of violence in adolescence and early adulthood.
The COSMIC project uses system dynamic and agent-based modelling to better understand how health systems function and respond to health programmes, such as payment for performance schemes.
UK-wide study explores how Covid is impacting young people (aged 15-25) over time. We are investigating how Covid experiences, including Long Covid, intersect with health, wellbeing, inequalities, and futures.
The COVID-19 Surveillance Intensification Ghana Network is a multidisciplinary team working to improve tracking of the COVID-19 epidemic in Ghana and support response efforts.
Driving clinical & biomedical research to improve the recognition, diagnosis and treatment of ME/CFS.
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Dagu aims to develop Ethiopian excellence in public health evaluation and improve quality and utilisation of primary and community-based health care services.
The DCMG aims to become the world-leading centre of excellence in evaluating methods for improving data collection in global health research.
Seeking to measure and solve the mystery of a kidney disease epidemic which is leading to the premature deaths of thousands of young people in low and middle income countries.
Participatory research to promote health and equity
The Disability Research Group at the MRC/UVRI & LSHTM Uganda Research Unit, conducts research to improve the health, development and quality of life of people with disabilities in East Africa.
The Disease Control Priorities 3 (DCP3) UHC Country Translation is a multi-year project, designed to respond to the increasing need of low and middle-income countries for technical guidance and support in priority setting and in accelerating progress towards Universal Health Coverage.
Evaluating the impact of the Determined, Resilient, Empowered, AIDS-free, Mentored, and Safe (DREAMS) Partnership
The purpose of this project is to map the geographical distribution of resistance mutations in African Plasmodium falciparum malaria.
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The Ebola vaccine projects – EBOVAC1, EBOVAC2, EBODAC and EBOMAN – are a series of trials and associated projects which aim to assess a novel prime-boost preventive vaccine regimen against Ebola Virus Disease (EVD).
This project aims to unify and enhance the economic evaluation of health impacts from climate action by developing globally consistent, accessible guidelines.
A diverse team capitalising on research opportunities offered by routinely collected data, bringing methodological rigour to provide real-world evidence for important questions regarding human health.
Combining high quality reproducible parasite drug sensitivity tests and genomics to detect malaria drug resistance and support antimalarial drug policy in West Africa
The Erythema Nodosum Leprosum International STudy (ENLIST) group is an international partnership between seven countries focused on improving the understanding and treatment of Erythema nodosum leprosum (ENL).
The Entebbe Mother and Baby Study (EMaBS) is a unique birth cohort, on-going in Africa.
The Entebbe Mother and Baby Study (EMaBS) is a unique Ugandan birth cohort that began as a trial [ISRCTN32849447], designed to investigate the potential benefits of treating worm infections during pregnancy and early childhood. Today, EMaBS serves as a valuable resource for investigating how early life experiences influence health outcomes in tropical settings.
The Environment and Health Modelling Lab creates and applies cutting-edge statistical methods to understand the interactions between climate change, environment and human health.
The focus for the London School of Hygiene & Tropical Medicine’s work on water, sanitation, hygiene and health.
This project investigates how Brazil’s national programme for improving primary care access and quality has affected inequalities in the financing and delivery of primary care.
Effect of Remote Ischaemic Conditioning on clinical outcomes in ST-segment elevation myocardial infarction patients undergoing Primary Percutaneous Coronary Intervention (ERIC-PPCI).
Research question: how effective and cost-effective is emergency surgery for patients with common acute conditions presenting as emergency admissions to NHS hospitals.
This project worked collaboratively with researchers at LSHTM and academics and researchers in Yemen to estimate mortality in Yemen employing a range of novel methods.
ZIKAlliance is a multinational and multi-disciplinary research consortium comprised of 53 partners worldwide and coordinated by Inserm, the French National Institute of Health and Medical Research.
Developing disease, behavioural and economic models to assess whether and how to intervene to improve global health.
Piloting and evaluating a tool to help LSHTM and our partners establish strong foundations and equitable processes for our research partnerships.
African ecosystems are highly vulnerable to climate change, with implications for health. This project will build evidence for a Planetary Health approach to policy making in Sub Saharan Africa.
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Working closely together with government policymakers and food system stakeholders, including farmers, retailers and consumers, the FACE-Africa project aims to jointly generate evidence to inform climate change adaptation strategies in food systems.
FIEBRE aims to reveal leading causes of fever in sub-Saharan Africa and southeast Asia. What are the main infections causing fever in children and adults, and how should they be treated?
The Forms of Care project ethnographically examined practices of 'not doing' in UK palliative and end-of-life care practice, and how these may be an active and valuable form of care.
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Understanding the mechanistic pathways of extreme heat and poor pregnancy outcomes to develop evidence-based and sustainable interventions.
An inter-disciplinary research group with expertise on violence against women, violence against children, violence against men, violence among same-sex people, migration, labour exploitation and human trafficking. A WHO Collaborating Centre since 2019.
Welcome to the General Population Cohort (GPC), a community based platform in rural Uganda for understanding health trends in Africa since 1989
Investigating genetic mechanisms underlying attractiveness of humans to mosquitoes.
The Global Asthma Network was established in 2012 to improve asthma care globally, with a focus on low- and middle-income countries, through enhanced surveillance, research collaboration, capacity building and access to quality-assured essential medicines.
Eye Health is essential to Child Health. We work to ensure that all children are getting access to eye health services to ensure they have the best vision possible.
A world-leading group working on a diverse portfolio of health economics research, with work ranging from developing innovative methods and empirical research to policy engagement and impact.
An independent group of influential experts with a commitment to tackling global challenges in food and nutrition security.
Supporting government and partners in strengthening health systems for better mental health of Syrian refugees and host communities in Lebanon.
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Developing surveillance and research in Eastern Ethiopia to improve maternal and child health.
Former football players are taking part in a major study to investigate effects of the sport on brain health.
We are a group of over 50 staff with internationally recognised expertise in a wide range of disciplines including health economics, policy analysis, public health, epidemiology and social science.
The Health Equity Action Lab is an international team of infectious disease epidemiologists and public health researchers dedicated to building a more just society.
High-impact research on health financing to improving health service delivery and equity in low and middle-income countries
Promoting research, education and knowledge translation to improve health and health equity in populations affected by humanitarian crises.
The HPP Debated blog offers news, comment and analysis on the latest research published in Health Policy and Planning.
The NIHR-funded Health Protection Research Unit in Health Analytics & Modelling is a partnership between LSHTM, Imperial College and the UKHSA to protect the health of the nation through pioneering modelling research.
Presenting the health systems research being undertaken by the London School of Hygiene & Tropical Medicine as well as listing relevant teaching programmes, resources and events.
Strengthening health systems through evidence-based and interdisciplinary research
The overarching purpose of this award is to provide an intellectual and policy history of ‘health systems’ thinking.
Healthcare-Associated Infection (HAI) Interest Group aims to promote research and awareness on preventing and controlling infections in healthcare settings. Dedicated to improving healthcare patient, staff and visitor outcomes through interdisciplinary collaboration, implementation research, evidence-based practices and research dissemination.
The UNITAID/PSI HIV Self-Testing Africa (STAR) Project is a four-year initiative to catalyse the market for HIV self-testing.
Evaluating the impact of Peer Advocates on the use of health care for adults in London who are homeless.
This study aims to contribute to the development and implementation of a controlled human infection model for schistosomiasis that can be used to test innovative and early proof-of-concept candidate schistosomiasis vaccines.
Our facility is open to the whole scientific community to study the human malaria parasites and their relationship with mosquito vectors.
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We are focused on improving outcomes for people with kidney and cardiovascular disease in the UK.
IDEAS aims to improve the health and survival of mothers and babies through generating evidence to inform policy and practice. Working in Ethiopia, North-Eastern Nigeria and the state of Uttar Pradesh in India, IDEAS uses measurement, learning and evaluation to find out what works, why and how in maternal and newborn health programmes.
An NIHR Global Health Research Group for Improving Hypertension Control in Rural sub-Saharan Africa (IHCoR-Africa)
Innovative Methods and Metrics for Agriculture and Nutrition Actions (IMMANA) is a five-year programme which will accelerate progress on tools, data and capacity needed to guide evidence-based policy in agriculture-food systems, nutrition and health.
IMPALA is a phase 3, randomised, open-label clinical trial testing the effectiveness of the novel 2-monthly injectable long-acting (LA) antiretroviral therapy (cabotegravir LA plus rilpivirine LA) compared to continuation of daily oral antiretroviral therapy in people with a history of sub-optimal HIV control in sub-Saharan Africa.
IMPALA is a phase 3, randomised, open-label clinical trial testing the effectiveness of the novel 2-monthly injectable long-acting (LA) antiretroviral therapy (cabotegravir LA plus rilpivirine LA) compared to continuation of daily oral antiretroviral therapy in people with a history of sub-optimal HIV control in sub-Saharan Africa.
IMPRESS investigates whether enhanced management practices can improve newborn survival and the quality of clinical care in hospitals in Malawi.
Investigating quality improvement in general practices – what do they do and how do they do it? A survey of GPs and Practice Managers.
Improving Hospital Opioid Substitution Therapy (iHOST): implementation and assessment of an intervention to reduce late presentations, discharges against medical advice and repeat admissions among people who use opioids.
The IMPULSE study aims to improve newborn routine data quality and use in high mortality settings for Every Newborn to survive and thrive.
Academic research group describing and explaining regional and socio-demographic differences in cancer outcomes, to influence policy and improve outcomes for all.
The Injury Epidemiology and Prevention Research Group (IEPRG) conducts research in the epidemiology and prevention of injuries, with a particular focus on road traffic injuries.
INSPIRE strengthens population health research across Africa, connecting 20 HDSS sites to harmonize data, enhance research, and promote data-driven decision-making through FAIR data principles.
INTEGRATE seeks to use evidence from routinely collected electronic health record data to inform and evaluate healthcare guidance, to maximise benefits for the health of the population.
Developing tools, techniques and evidence about disability, leading to scalable interventions for public health and development.
The International Centre for Eye Health is a research and education group working to improve eye health and eliminate avoidable visual impairment and blindness, with a focus on low-income populations.
Facilitating the development, evaluation and implementation of accessible, quality assured in-vitro diagnostics for global health, through information sharing and advocacy.
Collaborating with international research partners to improve health in low and middle-income countries.
This mixed-method study combines a four-wave longitudinal quantitative design with qualitative interviews to explore the predictors of intimate partner violence in Mwanza, Tanzania.
The Invisible Girls research programme aims to raise the visibility and voices of child domestic workers in Southeast Asia. This programme is designed to generate intervention-focused evidence to guide programming and policies that promote a brighter future for child domestic workers, and ultimately reduce children’s engagement as domestic workers.
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Kilgoris (Masai for ‘Unstable’ to describe the ever-changing nature of HIV-1) is a clinical study that investigates the ability of the human body to control the amount of free Human Immunodeficiency Virus-1 (HIV-1) early in infection without antiretroviral drugs.
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LAMP4Yaws is a multi-country EDCTP-funded project, assessing the real-life accuracy of a new diagnostic test in yaws-endemic areas of Ghana, Côte d’Ivoire and Cameroon, to support WHO’s yaws eradication strategy.
Developing evidence-led actions for financing primary healthcare in LMICs.
LASER combines expertise in the fields of spatial statistics and GIS technology, quantitative epidemiology and operational research to build the evidence-base around diseases of poverty and the communities they affect.
Promoting best practice in learning and teaching through educational research (to join, contact Anna Foss).
A project with the Ethiopian Public Health Institute and University of Gondar to develop Ethiopian institutional capacity for public health and health system research focussing on women’s and children’s health.
Exploring the potential of communities and social norms to prevent violence against and exploitation of children and adolescents.
Investigating the best use of liver transplantation to treat patient’s with hepatocellular carcinoma (HCC).
Our research group is focussed on the discovery, evaluation and implementation of novel interventions for the control vector borne diseases, from basic scientific studies in the laboratory understanding vector-host-pathogen interactions, to large scale field trials.
Collaborating with leading scientists from Germany, UK, and further afield to conduct, and promote discussion around, cutting-edge research on global health issues including migration, gender, health equity and health systems.
With one of the largest groupings of Neglected Tropical Diseases researchers, the London School of Hygiene and Tropical Medicine is internationally recognised as a leading centre for NTD research. The NTD Network is designed to make it easier for you to find and access that expertise.
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Computable General Equilibrium (CGE) modelling of health, health policy or broader policy with implications for health
Violence, mental health, biological changes to the immune system and HIV risk: a three-year mixed-method, longitudinal study with 1000 women in Nairobi, Kenya
The Malaria Reference Laboratory (MRL) provides laboratory reference and diagnostic parasitology of malaria, and surveillance data on all imported malaria reported in the UK.
MEIRU, formerly known as Karonga Prevention Study (KPS), has been making major research contributions to the understanding and control of long-term conditions, including HIV/AIDS, cardiovascular disease, diabetes and common mental health conditions in rural Karonga and urban Lilongwe, to complement its continuing research on infectious diseases.
The Maternal Health Group in the Department of Infectious Diseases and Epidemiolgy was created in 1989 and expanded in 2015 to include the Newborn Health and Stillbirth Team at LSHTM.
We conduct multidisciplinary research on the role of the private and public health sectors in delivering maternal and reproductive health care.
To better understand the mortality burden of antimicrobial resistance in low and middle income countries in sub-Saharan Africa.
Staff and research degree students in Department of Global Health and Development conducting interdisciplinary social science research to strengthen the health, wellbeing and voice of people affected by humanitarian crises.
Evaluating the impact of a multi-component menstrual health intervention in Ugandan secondary schools on girls’ education, health, and wellbeing.
We are an interdisciplinary group seeking to support collaborative research on Mental Health and Psychosocial Support (MHPSS) Research Network and its dissemination at LSHTM and partners.
Our research aims to develop new guidance for systematic reviewers when making a decision about whether or not to use a meta-analytical approach to the synthesis of quantitative evidence, with a particular emphasis on the synthesis of studies of complex interventions.
MaPs in ENL is the largest international multicentre randomised clinical trial on ENL treatment ever to be conducted in six leprosy referral centres in five countries.
A research collaboration addressing pressing issues facing health systems globally and at a national level in South Africa – the impacts of and response to migration and its intersection with gender.
This site exists to support researchers from the social and medical sciences with the analysis of incomplete datasets, and as a focus of statistical research in this area.
MONKEYBAR is a project seeking to identify risk factors and control strategies for Plasmodium knowlesi, a zoonotic malaria carried by macaques.
The MOVIE-TRACE project aims to improve our understanding of the epidemiology of MPOX in Africa.
The International Statistics and Epidemiology Partnership aims to define and implement a sustainable strategy to expand capacity in applied medical statistics in sub-Saharan Africa.
Evaluating the impact of the MTV Shuga mass media campaign. Centred around a TV drama, the campaign is designed to improve the sexual health of young people.
MITU’s mission is to contribute to improving health through the development and evaluation of interventions against HIV and other health problems.
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The Nairobi Early Childcare in Slums (NECS) study is building an understanding of the early childhood development in Nairobi slums, with a particular focus on the informal childcare sector.
Revealing the changing sexual attitudes and behaviour of the British population, Natsal is one of the largest scientific studies of sexual health and lifestyles in the world.
LSHTM undertakes evaluations and implementation research with partners from academic institutions, key UN agencies and leading NGOs, focussing on the delivery, effectiveness and strengthening of primary level NCD care in humanitarian settings.
A multi-disciplinary team of researchers from the UK, Bolivia, Mozambique, Peru, The Netherlands and Zambia aiming to develop and test an artificial intelligence-supported point-of-care ultrasound (AI-POCUS) to improve the reach and quality of tuberculosis screening in vulnerable adults and children.
A multidisciplinary team of researchers from UK, Uganda and Kenya aiming at identifying structural, modifiable determinants of impaired vaccine impact in vulnerable communities and develop integrated strategies to address them.
The NIHR Health Protection Research Unit is a collaborative partnership delivering research to support vaccination services in the UK.
The NIHR Public Health PRU (PH-PRU) conducts public health research with a social determinants focus.
The NIHR School for Public Health Research is a collaborative partnership between nine leading academic centres in England. We work with policy and practice colleagues to deliver high quality research.
Our overall aim is to develop and extend a strong research partnership to conduct policy-relevant research to enhance mobile adolescents and young people resilience to navigate access to sexual and reproductive health services thereby contributing to their improved health and wellbeing.
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The Obuntu Bulamu randomized control trial is a four-year research study conducted across 20 primary schools in Wakiso and Masaka districts of Uganda. It seeks to investigate the impact of Obuntu Bulamu project interventions between 2017-2019 on participation, inclusion, and quality of life of 200 children with disabilities.
There is a mystery epidemic of Chronic kidney disease of unknown cause (CKDu) affecting agricultural and non-agricultural communities in Mesoamerica. This disease has reduced the life expectancy of thousands and caused the deaths of tens of thousands young males and females.
A UK cohort study that aims to measure the impact of long COVID upon quality of life, and on costs to the NHS and the wider economy.
The OPT-SMC project supports national malaria control programmes in West and Central Africa to conduct implementation research on Seasonal Malaria Chemoprevention by providing grants and technical assistance, and facilitates sharing of information and expertise between countries. The project is a partnership between the national malaria control programmes in 13 countries.
ORCA aims to improve the quality of health data in Ethiopia by supporting analysts at the Ministry of Health, Ethiopia.
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PARES is a NIHR funded consortium of partners from Europe and Africa, dedicated to researching and building partnerships for resilience. We are identifying best-practices and developing indicators for engaging communities in crisis-response.
Advancing healthcare knowledge through patient and public involvement.
The Pathfinder Initiative, funded by the Wellcome Trust with support from the Oak Foundation, supports rapid progress towards a healthy, zero-carbon society.
Patients’ views are essential to achieving high-quality healthcare. Our PROMs research is helping to improve patient care by evaluating the performance of health care providers and guiding NHS reforms.
The PAVE team are an anthropological led team including social scientists, political theorists, epidemiologists, and modellers. Working in an innovative cross-disciplinary approach we address two public health problems: violence and epidemics and the intersections between them.
PENDA is consortium lead by the International Centre for Evidence in Disability, it is focused on creating evidence to achieve long-term improved wellbeing and inclusion of people with disabilities in Low and Middle Income Country's (LMICs), through building knowledge, people and tools.
Investigating the effectiveness of different treatments for Type 2 Diabetes Mellitus.
An independent evaluation of England's Pharmacy First service. Launched in 2024, we will study implementation and impact of the new scheme which enables pharmacies to supply prescription-only medicines for seven common conditions.
PIC4C Scale-up is a collaborative implementation research project to inform and support scale up of the Primary Health Integrated Care project for Chronic Conditions in Kenya and beyond.
Pilot RCT of a complex violence prevention intervention.
This project is funded by a Wellcome Trust Medical Humanities New Investigator Award, awarded to Dr Alex Mold in 2013 and is based in the Centre for History in Public Health at the LSHTM.
The Policy Innovation and Evaluation Research Unit (PIRU) brings together leading health and social care expertise to improve evidence-based policy-making and its implementation across the National Health Service, social care and public health.
Researching health at the interface of economics and politics
A major study in South Africa and Zambia to test a new approach to the prevention and control of HIV in Africa.
PHI-Lab uses insights from epidemiology, economics, sociology and geography to understand and change the social, economic and environmental system drivers of population health.
The Population Studies Group (PSG) is engaged in the measurement and explanation of population trends and in the evaluation of attempts to modify them.
How people respond to vaccines, and how well they work, varies between populations. POPVAC’s goal is to understand these differences in order to identify strategies of improving vaccine effectiveness.
Our trial evaluates Positive Choices, a whole-school social-marketing intervention to promote sexual health across 50 secondary schools in England.
Power and Protection is home to original films, archival material, and resources about the history of the Court of Protection in England and Wales, and the evaluation of ‘mental capacity’.
The Praziquantel in Preschoolers trial (PIP) aims to find the right treatment dose of praziquantel for preschool children living with intestinal schistosomiasis in Uganda.
Training teachers on emotional self-regulation and positive discipline to prevent and reduce violence against children in schools in Nyarugusu refugee camp.
A randomised double-blind controlled phase III study to compare the efficacy and safety of intravenous ferric carboxymaltose with placebo in patients with anaemia undergoing major open abdominal surgery.
Brings together researchers, providers and policymakers working on PHC in all settings; to identify opportunities to build collaborations, support shared learning and strengthen knowledge in this area.
Studying private healthcare provision – how it works, how to improve it and where it fits in universal health care
Developing an evidence base and platform for action around how violence in childhood and adolescence affects child labour, participation in skills programmes and employment outcomes in Uganda.
The Policy Research Unit in Commissioning and the Healthcare System (PRUComm) provides evidence to the Department of Health to inform the development of policy in the National Health Service. We focus on maximising outcomes for patients.
Understanding, developing, and advocating for the arts and humanities within public health research, training, and practice.
The Public Health Research Consortium (PHRC) brings together senior researchers from 11 UK institutions in a new integrated programme of research, with the aim of strengthening the evidence base for interventions to improve health, with a strong emphasis on tackling socioeconomic inequalities in health.
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We will map and assess governance practices for vaccination services in a range of humanitarian responses; and identify recommendations for equitable vaccination delivery, with a focus on zero-dose communities.
The rapid mortality mobile phone surveys (RaMMPS) project is a new initiative to conduct mortality surveillance through mobile phone surveys in settings where alternative data are not available or where data collection has been interrupted because of epidemic outbreaks or other crisis situations.
REACH aims to describe the impact and costs of weather extremes on maternal and child health services to support preparedness at the district, facility and community levels in Brazil and Zambia.
Research capacity strengthening and knowledge generation to support preparedness and response to humanitarian crises and epidemics.
This project aims to assess the performance of e-pharmacies in India and Kenya and analyse regulatory systems for improving medicine quality, safety and accessibility.
The REPRIEVED trial aims to find out whether stent procedures improve quality of life and blood supply to the heart in people who have heart failure with preserved ejection fraction (HFpEF) and coronary artery disease.
A Consortium of institutions and individuals coming together to promote research on the impact of health and nutrition on the development, wellbeing, and education of school children and adolescents.
The Resilience Against Future Threats through vector control (RAFT) Research Programme Consortium (RPC) aims to address a range of urgent issues on mosquito-borne diseases, including insecticide resistance and emerging threats.
Improving health systems responsiveness to neglected health needs of vulnerable groups in Ghana and Vietnam.
The Resilient and Responsive Health Systems (RESYST) is an international research consortium that aims to enhance the resilience and responsiveness of health systems to promote health and health equity and reduce poverty.
Our MRF funded initiative aims to change outbreak and humanitarian policy and practice approaches and guidelines to improve engagement with communities and frontline health responders.
Multicentre prospective randomised open controlled trial aiming to evaluate the efficacy and safety of percutaneous coronary intervention compared to optimal medical therapy alone for ischaemic left ventricular dysfunction.
Exploring infidelity, romantic jealousy and intimate partner violence.
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A randomised controlled trial of an intervention delivered by mobile phone messaging to reduce sexually transmitted infections (STI) by increasing sexual health precaution behaviours in young people.
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The project aims to characterise global antibody targets during a controlled (and natural) human schistosomiasis infection among endemic populations.
The Schools Infection Survey (SIS) is a flagship study investigating the role of schools in the spread of COVID-19 and how transmission within and from schools can be minimised.
The Sustainable Evaluation through Analysis of Routinely Collected HIV data (SEARCH) is a collaboration between the London School of Hygiene & Tropical Medicine and the Ministries of Health in Malawi, Tanzania and Zambia, and is funded by the Bill & Melinda Gates Foundation.
Using participatory stakeholder elicitation, health economic modelling, and multi-criterion decision analysis to rank antimicrobial stewardship interventions from a One Health perspective in England, Senegal and Denmark.
National evaluation of the health and social impacts of selective licensing for private rented housing in England
Strengthening health service delivery and quality of care through high-impact, interdisciplinary research.
Our LSHTM team are conducting a multidisciplinary study using participatory, community-driven approaches to obtain evidence for improving sexual health services among older adults and informing relevant policy recommendations.
SHARE contributes to achieving universal access to effective, sustainable and equitable sanitation and hygiene by generating evidence to improve policy and practice worldwide.
Working in partnership across five institutions, we conduct multi-disciplinary research in Ghana and Ethiopia to improve experiences of severe and stigmatising neglected tropical diseases of the skin.
We are a group of multidisciplinary academics working on a diverse portfolio of epidemiology research, largely focused on skin disease.
SNMP is a set of tailored programmes on the theory and application of social norms in research and programme development through comprehensive training and mentorship.
SORT will assess inequalities in receipt of cancer treatments and the relative effectiveness and cost-effectiveness of curative surgery versus radiotherapy for three types of cancer (lung, oesophageal and bladder).
Funded by the Bill & Melinda Gates Foundation and facilitated by the London School of Hygiene and Tropical Medicine, SPEAK India brings together researchers and technical experts alike, with an aim to develop a consensus on the additional knowledge required to ensure VL transmission is successfully interrupted and elimination is sustained.
SSACAB brings together African and Northern academic and research institutions to develop and improve biostatistical skills among researchers.
Cross-faculty and cross-disciplinary group to promote STI research conducted at LSHTM
The NIHR Global Health Research Centre for Non-Communicable Disease Control in West Africa is part of the NIHR and hosted by LSHTM and the Ghana College of Physicians and Surgeons
200 million people still live in trachoma-endemic regions and are at risk of becoming blind despite concerted international effort to tackle the disease. With the clock ticking towards the 2020 elimination goal, novel strategies are urgently needed to accelerate and strengthen the SAFE strategy.
Recognising that people with psychosocial disabilities are best positioned to define their own needs, SUCCEED is co-producing the design and evaluation of community-based interventions for people with psychosis in Africa.
Sudan Research Group is a collaboration between humanitarian and public health academics, and Sudanese youth researchers and volunteers.
We are assessing how UK funding to Support the National Malaria Programme in Nigeria is affecting change.
This research project aims to improve surgical services for women with urinary incontinence in England.
SHEFS is a programme aiming to provide policy makers with novel, interdisciplinary evidence to define future food systems policies that deliver nutritious and healthy foods in an environmentally sustainable and socially equitable manner.
We conduct formative research into the health and wellbeing needs and priorities of host communities in which around 30 Anglo-American mines are situated, in eight countries.
A participatory evaluation of how UK charity National Ugly Mugs – a community-based violence prevention and support service – affects sex workers’ safety and mental health.
A five-year programme of research and evaluation funded by the UK Department of International Development (DFID). SWiFT assesses, evaluates and informs the International Labour Organisation’s DFID-funded “Work in Freedom” multi-country intervention to minimise women’s vulnerability to labour trafficking in South Asia and the Middle East.
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The Taiwan-UK SGS Health Research Network (TUSHRN) aims to further research on the health of sex, gender and sexuality (SGS) minorities in Taiwan and the UK.
Improving public health research in Tanzania through joint research and capacity-building, including through better communications and networking for LSHTM staff, students, and alumni in Tanzania.
Providing a focus for global research expertise in tuberculosis epidemiology, immunology, diagnosis and treatment.
The TB Drug Discovery Group at LSHTM is focused on advancing the development of drug regimens for the treatment of tuberculosis to counter the threat from AMR.
The TB Modelling Group uses mathematical models to better understand the natural history and epidemiology of tuberculosis, and to improve the contribution of modelling to policy decisions and implementation.
Addressing the health impacts of climate variability and climate change, and protecting UK public health through adaptation and mitigation actions.
Co-Create is a project designed to reduce obesity and its co-morbidities by working with adolescents, to create, inform and disseminate obesity-preventive, evidence-based policies, using a complex systems approach.
The DE-grading Epidemiology (DEEP) Network has been formed to encourage open debate about the use of algorithms to assess epidemiological studies, and maintain contacts between those of us who are working on these issues. It will pursue strategies to improve our ability to methodically and accurately integrate and interpret epidemiologic evidence.
The value and unexpected by-product of a community engagement strategy aimed at addressing the immunisation gap in north-west Ethiopia.
The Fleming Fund Fellowships provide training and mentorship to professionals in low- and middle-income countries to strengthen capacity in antimicrobial resistance (AMR) surveillance, research, and data analysis.
The Global Vector Hub is an open access, interactive resource. It has the capacity to transform vector research and vector control programmes, and to revolutionise our preparedness and ability to respond quickly and effectively to vector-borne disease outbreaks, around the world.
The Health Research Unit Zim (THRU ZIM) at the Biomedical Research and Training Institute conducts research aimed at improving health and wellbeing across the life-course. We focus on public health issues of relevance to Zimbabwe and the African region. Our research group is multidisciplinary and collaborates with a range of local and international academic institutions, so that we can access the expertise to conduct research to the highest standards.
The HPRU in Environmental Change and Health provides research to support decision making relating to the impacts and responses to the environmental changes that affect our health.
Addressing the major nutrition and food-related problems that affect human development and well-being, at national and global levels.
The O2O Project explored the potential of online networks to initiate social norms change about family planning in offline communities in Nairobi, Kenya during COVID-19.
Collecting data to understand reproductive health and experiences in England.
M. tuberculosis is a leading cause of meningitis in people living with HIV. Currently, over 50% of cases die and many survivors are left disabled. Finding better diagnostics and optimised treatments is a priority.
The SACHA Study team have been funded by the National Institute for Health Research to gather information which will help health services and systems in the UK to shape abortion care for the future.
SIPP is a mixed methods interdisciplinary evaluation of an intervention to reduce health harms and enhance service engagement among people who use crack cocaine in England.
Global trials aiming to reduce maternal mortality due to postpartum haemorrhage (PPH) using tranexamic acid (TXA).
This collaborative research project, funded by the National Institute for Health Research (NIHR), Health Services and Delivery Research Programme, examines the experiences of young people with sickle cell as they transition to adulthood and move from using child to adult services.
THRiVE’s mission is to empower African Institutions to become research engines for health innovations and evidence-based healthcare practices and policies.
Tight K is a study investigating whether maintaining serum potassium levels at ≥3.6 mEq/L is non-inferior to maintaining at ≥4.5 mEq/L on the occurrence of new onset atrial fibrillation dysrhythmia post-surgery in patients undergoing isolated CABG surgery
This website is created to facilitate an informal network for researchers using the Test-Negative-Design (TND) for studying the causes of COVID-19 infection. We will create a repository of papers about the use of the TND, and for questionnaires for use in TND studies of the causes of COVID-19.
An interdisciplinary network of trial managers, clinical research associates, data managers, epidemiologists, statisticians and practitioners with an interest and expertise in randomised controlled trials methods and delivery working across LSHTM and its partners.
The effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage: an international, randomised, double-blind, placebo-controlled trial.
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A specialist team ready to respond to disease outbreaks around the world before they develop into health emergencies. The team also conducts rigorous operational research and capacity strengthening to improve epidemic preparedness.
We explore how formal and informal structures and practices in health systems interact with the socio-political context to undermine accountability and encourage corruption in Malawi and Nigeria, and ask how to overcome them.
A unique multi-disciplinary collaboration of five leading research institutions in Africa and Europe seeking to inform HIV prevention technologies for African women and girls through behavioural science.
We use Shigella infection to discover new roles for the cytoskeleton in host defence, and use zebrafish to study the cell biology of infection in vivo.
Investigating whether dogs could be trained to identify unique odours associated with coronavirus infection
Understanding and preventing sexual and other forms of violence against children in Zanzibar.
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Bringing together research from vaccine design and immunological characterisation through clinical trials to epidemiological evaluation, safety, economic, social science and policy analysis.
Using model-based drug development methods (PK/PD) to accelerate vaccine dose decision making.
Together for Girls and LSTHM co-created a course to support early career researchers in LMICs to conduct research with VACS data and communicate their findings to policymakers in their respective countries.
Development work for an evaluation of a complex intervention to increase uptake of vaccinations in pregnancy among socio-economically and ethnically diverse populations.
The purpose of VITALITY trial is to establish whether supplementation with vitamin D and calcium optimises musculoskeletal health among peripubertal children with HIV in Zimbabwe and Zambia.
This is the first RCT to investigate this intervention to improve bone health in HIV children.
PI: Prof Rashida Ferrand (LSHTM/ Biomedical Research & Training Institute (BRTI), Harare)
Funder: EDCTP
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The is a joint project between the LSHTM and the Natural History Museum (London) providing live schistosome life-cycle stages and their intermediate snail hosts for schistosomiasis research purposes.
We aim to recruit and train the best young clinical and non-clinical scientists with an interest in global health research, to provide them with the support, training and academic environment they need to develop into independent researchers, and to facilitate their academic and clinical career progression.
LSHTM is one of eight WHO Sexually Transmitted Infection (STI) Collaborating Centres worldwide. This Centre is closely aligned with LSHTM’s Sexually Transmitted Infections Research Interest Group (STIRIG), which is made up of more than 50 cross-Faculty, interdisciplinary LSHTM researchers and students conducting research on sexual health and STIs. The Centre works with the WHO Global HIV, Hepatitis and STIs Programme (HHS), the UNDP/UNFPA/UNICEF/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction (HRP), and a network of international collaborators on activities to improve the prevention, control and management of STIs worldwide.
The WOMAN trial, coordinated by the London School of Hygiene & Tropical Medicine (LSHTM) Clinical Trials Unit (CTU) is an international clinical trial of the effect of tranexamic acid on death, hysterectomy and other maternal outcomes, in women with PPH.14.
The World AsthmaPhenotypes Study (WASP) aims to better understand and characterise different sub-types (phenotypes) of asthma.
Our lab is in the Department of Infection Biology (DIB) at the London School of Hygiene and Tropical Medicine (LSHTM) where we research the molecular mechanisms of bacterial pathogenesis and utilise bacteria as biotechnologies for the production of glycoconjugate vaccine candidates against bacterial infectious diseases of global relevance.
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Yaba Guy Che will explore whether a community-based digitally supported care pathway, integrated into the existing primary health system, improves the coverage of HIV, sexually transmitted infections (STIs) and non-communicable disease (NCD) services among men.
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A multinational and multidisciplinary consortium implementing critical research on the existing Zika virus outbreak whilst preparing a sustainable response capacity for future emerging epidemics in Latin America.
The Zipime Weka Schista! (Do self-testing sister!) study aims to integrate multi-pathogen home self-sampling for genital infections including female genital schistosomiasis, HPV, HIV and STI to increase case-detection for girls and women of reproductive age.