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Hydroxychloroquine was quickly thrown into a global spotlight after it garnered simultaneous praise and criticism from a number of high-profile sources.   The drug has since been investigated in several randomised clinical trials and observational studies. Most studies to date have shown no evidence of a benefit of hydroxychloroquine as a treatment for patients admitted to hospital who already have COVID-19.  
As I left the UN General Assembly High-Level Meeting on Ending TB in New York two years ago, there was renewed hope that this could be a turning point for accelerating progress against tuberculosis (TB). But COVID-19 has shifted global TB control from acceleration into reverse.
Also contributing to this opinion piece were: Sharifah Sekalala, Associate Professor at the University of Warwick; Judith Bueno de Mesquita, Co-Deputy Director at the Human Rights Centre, University of Essex; Claire Lougarre, Lecturer and Director of the Centre for Health Ethics and Law at the University of Southampton; and Michel Coleman, Professor of Epidemiology and Vital Statistics at the London School of Hygiene & Tropical Medicine.
Antimicrobial resistance threatens one of the most important infrastructures created in the past century: antibiotics. At first glance, it may seem odd to think of antibiotics as infrastructure. Think again. These drugs are everywhere. So engrained has their use become that we now expect – rather than pray for – infectious diseases to be cured. But antibiotics are not only used in the treatment of acute infections.
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