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Schista Community Worker at a participant's home with the self-sampling portable mini lab. Credit: A.Bustinduy

Zipime Weka Schista! (Do self-testing sister!)

One-stop home self-sampling for female genital schistosomiasis, HPV, Trichomonas and HIV as a cost-effective and self-empowering strategy to increase case-detection and improve access to care for women of reproductive age in Zambia

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About

The Zipime Weka Schista (Schista! for short) study aims to integrate female genital schistosomiasis, a neglected tropical gynecological disease, within the wider sexual and reproductive health screening strategies.

 

Research

Integration of home self-sampling for the screening of female genital schistosomiasis with human papillomavirus (HPV) and self-testing for HIV and sexually transmitted infections is a cost-effective and self-empowering strategy that will increase the detection of cases and improve access to care for girls and women of reproductive age in sub-Saharan Africa.

Who we are
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The Zipime Weka Schista! (Schista! for short) study brings together world-wide experts from the fields of female genital schistosomiasis, cervical cancer and HIV to propose an innovative approach to integrate multi-pathogen home-based self-sampling and testing.

Principal Investigator

Site Principal Investigator - Zambia

Study Manager

  • Nanyangwe Siuluta

Co-investigators

PhD students

  • Olimpia Lamberti - LSHTM/Nagasaki
Research
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This study is designed as a holistic approach to FGS detection at-scale in the community and within the wider scope of female sexual and reproductive health surveillance and linkage to care in Zambia. Female genital schistosomiasis (FGS) causes substantial morbidity in the female genital tract. Home-based genital self-sampling procedures allow discrete and convenient testing for participants with difficulty accessing a medical facility. Extending the possibility of home-based sampling for S. haematobium would allow improved diagnosis and treatment of this important condition.

This study’s emphasis on home-based testing compared with clinic-based testing will evaluate an innovative approach for future expansion of surveillance of FGS using diagnostics with high feasibility for use at scale with a special emphasis on health economics to aim for sustainability.

 

Publications

Read our publications.

Schista Publications list
Chapter One - An update on female and male genital schistosomiasis and a call to integrate efforts to escalate diagnosis, treatment and awareness in endemic and non-endemic settings: The time is now
Amaya L. Bustinduy, Bodo Randriansolo, Amy S. Sturt, Seke A. Kayuni, Peter D.C. Leustcher, Bonnie L. Webster, Lisette Van Lieshout, J. Russell Stothard, Hermann Feldmeier, Margaret Gyapong
2022
Advances in Parasitology, Volume 115. doi.org/10.1016/bs.apar.2021.12.003.
Updates
Updates List Block
Schista study team celebrate International Midwives Day

We celebrated the work of our team of midwives - Alice, Agness, Kaziku and Mercy and a blog from our wonderful midwife - sister Kaziku posted at the MARCH Centre.

Schista! study team present on International Women's Day

Our study manager Dr. Nanyangwe Siuluta and our Schista Community Worker Ruth Mwansa presented at the ISNTD panel discussion on International Women's Day integrating FGS into the Health System

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The Schista study recruitment

The Schista study started recruitment on January 19th. Our teams are in the field going door to door recruiting participants and implementing self-sampling through their 'mini' portable laboratories.

Schista! team photo
Schista! study officially launched

On August 31st the Schista! study was officially launched. District Health Officers from Kafue, Chongwe and Livingstone and NTD officers from the Ministry of Health attended the virtual event.

Amaya Bustinduy, PI of the Zipime Weka Schista project awarded Future Leaders Fellowship

Amaya Bustinduy, PI of the Zipime Weka Schista project was awarded the Future Leaders Fellowship to conduct the work. Read more about the award.