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Dr Amaya Bustinduy

MD MPH PhD FRCPCH

Associate Professor
in Tropical Paediatrics

Room
301

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Tel.
+44-020-79272220

Amaya trained in paediatrics and infectious diseases in the US and started working on helminthic infections, mainly schistosomiasis, and their impact on child health in Coastal Kenya in 2009. She is foremost a field clinical epidemiologist and has investigated a broad range of disease manifestations in children related to neglected tropical parasitic diseases (NTD) such as malnutrition and anaemia. Other work has included profiling pro-inflammatory cytokines in schistosomiasis and drug (praziquantel) efficacy PK/PD studies in young children in Uganda. (PIP trial: https://www.lshtm.ac.uk/research/centres-projects-groups/pip-trial)

She is interested in community-based diagnosis of female genital schistosomiasis, validating diagnostic tools at the point-of-care and its association with cervical cancer, STIs and HIV. (BILHIV study: https://www.lshtm.ac.uk/node/76621)

She is currently one of the Department Research Degree Coordinators (DRDC).

 

Affiliations

Department of Clinical Research
Faculty of Infectious and Tropical Diseases

Centres

Centre for Maternal Adolescent Reproductive & Child Health (MARCH)

Teaching

Amaya has been involved in teaching at the East African DTM&H since 2013 and is now the deputy director of the course since 2016. She teaches regularly at the London DTMH and PGDTN and Liverpool (LSTM)..

She currently supervises PhD and MSc students at LSHTM, and co-supervises students at LSTM from the MSc in Global Health and Tropical Paediatrics.

Research

  • Female genital schistosomiasis-new diagnostics at a community level
  • Clinical trials involving Pk/PD of antiparasitic drugs in children
  • Point-of-care diagnostics for schistosomiasis (infection and morbidity)
  • HIV-schistosomiasis and other helminthic co-infection and their impact on child health
  • Preschool schistosomiasis and integration of treatment into the Integrated management of childhood illnesses (IMCI)
  • Environmental enteropathy in relation to helminthic diseases
Research Area
Child health
Clinical trials
Diagnostics
Helminths
Parasites
Adolescent health
Global Health
Medicines
Pharmacokinetics
Discipline
Epidemiology
Medicine
Nutrition
Operational research
Parasitology
Pharmacology
Disease and Health Conditions
Infectious disease
Malnutrition
Lymphatic filariasis
Neglected Tropical Diseases (NTDs)
Schistosomiasis
Country
Kenya
Uganda
Zambia

Selected Publications

Use of facemasks and other personal preventive measures by Hajj pilgrims and their impact on health problems during the Hajj.
Alasmari AK; Edwards PJ; Assiri AM; Behrens RH; Bustinduy AL
2020
Journal of Travel Medicine
Intestinal Schistosomiasis and Giardiasis Co-Infection in Sub-Saharan Africa: Can a One Health Approach Improve Control of Each Waterborne Parasite Simultaneously?
Archer J; O'Halloran L; Al-Shehri H; Summers S; Bhattacharyya T; Kabaterine NB; Atuhaire A; Adriko M; Arianaitwe M; Stewart M
2020
Tropical medicine and infectious disease
Could This Child Have Schistosomiasis?: When to Suspect It and What to Do About It.
Bustinduy AL; Edielu A; Sturt AS
2020
Pediatruc Infectious Diseases Journal
Population Pharmacokinetics of Praziquantel in Pregnant and Lactating Filipino Women Infected with Schistosoma japonicum.
Bustinduy AL; Kolamunnage-Dona R; Mirochnick MH; Capparelli EV; Tallo V; Acosta LP; Olveda RM; Friedman JF; Hope WW
2020
Antimicrobial Agents and Chemotherapy
Integration of prevention and control measures for female genital schistosomiasis, HIV and cervical cancer
Engels D; Hotez PJ; Ducker C; Gyapong M; Bustinduy AL; Secor WE; Harrison W; Theobald S; Thomson R; Gamba V
2020
Bulletin of the World Health Organization
Schistosomiasis-associated pulmonary arterial hypertension: a systematic review.
Knafl D; Gerges C; King CH; Humbert M; Bustinduy AL
2020
European Respiratory Review
Application of a recombinase polymerase amplification (RPA) assay and pilot field testing for Giardia duodenalis at Lake Albert, Uganda.
Molina-Gonzalez SJ; Bhattacharyya T; AlShehri HR; Poulton K; Allen S; Miles MA; Arianitwe M; Tukahebwa EM; Webster B; Russell Stothard J
2020
Parasites and Vectors
A cross-sectional study of periportal fibrosis and Schistosoma mansoni infection among school-aged children in a hard-to-reach area of Madagascar.
Russell HJ; Penney JMS; Linder C; Joekes EC; Bustinduy AL; Stothard JR; Rakotomampianina DAL; Andriamasy EH; Mahary LR; Ranjanoro EP
2020
Transactions of the Royal Society of Tropical Medicine and Hygiene
Acceptability and feasibility of genital self-sampling for the diagnosis of female genital schistosomiasis: a cross-sectional study in Zambia
Rutty Phiri C; Sturt AS; Webb EL; Chola N; Hayes R; Shanaube K; Ayles H; Hansingo I; Bustinduy AL
2020
Wellcome Open Research
Beyond the barrier: Female Genital Schistosomiasis as a potential risk factor for HIV-1 acquisition.
Sturt AS; Webb EL; Francis SC; Hayes RJ; Bustinduy AL
2020
Acta Tropica
Genital self-sampling compared with cervicovaginal lavage for the diagnosis of female genital schistosomiasis in Zambian women: The BILHIV study.
Sturt AS; Webb EL; Phiri CR; Mweene T; Chola N; van Dam GJ; Corstjens PLAM; Wessels E; Stothard JR; Hayes R
2020
PLoS Neglected Tropical Diseases
Female genital schistosomiasis and HIV/AIDS: Reversing the neglect of girls and women.
Hotez PJ; Harrison W; Fenwick A; Bustinduy AL; Ducker C; Sabina Mbabazi P; Engels D; Floerecke Kjetland E
2019
PLoS Neglected Tropical Diseases
Focused Assessment with Sonography for Urinary Schistosomiasis (FASUS)-pilot evaluation of a simple point-of-care ultrasound protocol and short training program for detecting urinary tract morbidity in highly endemic settings.
Remppis J; Verheyden A; Bustinduy AL; Heller T; García-Tardón N; Manouana GP; Obiang R; Adegnika AA; Grobusch MP; Ramharter M
2019
Transactions of the Royal Society of Tropical Medicine and Hygiene
Schistosoma mansoni Infection as a Predictor of Low Aerobic Capacity in Ugandan Children.
Smith C; McLachlan G; Al Shehri H; Adriko M; Arinaitwe M; Atuhaire A; Muheki Tukahebwa E; LaCourse EJ; Stanton M; Stothard JR
2019
American Journal of Tropical Medicine and Hygiene
Cognitive deficits and educational loss in children with schistosome infection-A systematic review and meta-analysis.
Ezeamama AE; Bustinduy AL; Nkwata AK; Martinez L; Pabalan N; Boivin MJ; King CH
2018
PLoS neglected tropical diseases
Schistosomiasis in Africa: Improving strategies for long-term and sustainable morbidity control.
French MD; Evans D; Fleming FM; Secor WE; Biritwum N-K; Brooker SJ; Bustinduy A; Gouvras A; Kabatereine N; King CH
2018
PLoS neglected tropical diseases
Point-of-care tests for infectious diseases: barriers to implementation across three London teaching hospitals.
Bustinduy AL; Jeyaratnam D; Douthwaite S; Tonkin-Crine S; Shaw R; Hyrapetian L; Sevdalis N; Goldenberg S; Adams EJ; Sharland M
2017
Acta paediatrica (Oslo, Norway
Paediatric and maternal schistosomiasis: shifting the paradigms.
Bustinduy AL; Stothard JR; Friedman JF
2017
British medical bulletin
One hundred years of neglect in paediatric schistosomiasis.
Bustinduy AL; Wright S; Joekes EC; Kabatereine NB; Reinhard-Rupp J; King CH; Stothard JR
2017
The Journal of parasitology
Praziquantel for the treatment of schistosomiasis during human pregnancy.
Friedman JF; Olveda RM; Mirochnick MH; Bustinduy AL; Elliott AM
2017
Bulletin of the World Health Organization
High burden of Schistosoma mansoni infection in school-aged children in Marolambo District, Madagascar.
Spencer SA; Penney JMSJ; Russell HJ; Howe AP; Linder C; Rakotomampianina ALD; Nandimbiniaina AM; Squire SB; Stothard JR; Bustinduy AL
2017
Parasites & vectors
Predictors of fever-related admissions to a paediatric assessment unit, ward and reattendances in a South London emergency department: the CABIN 2 study.
Bustinduy AL; Chis Ster I; Shaw R; Irwin A; Thiagarajan J; Beynon R; Ladhani S; Sharland M; CABIN network
2016
Archives of disease in childhood
Expanding Praziquantel (PZQ) Access beyond Mass Drug Administration Programs: Paving a Way Forward for a Pediatric PZQ Formulation for Schistosomiasis.
Bustinduy AL; Friedman JF; Kjetland EF; Ezeamama AE; Kabatereine NB; Stothard JR; King CH
2016
PLoS neglected tropical diseases
Population Pharmacokinetics and Pharmacodynamics of Praziquantel in Ugandan Children with Intestinal Schistosomiasis: Higher Dosages Are Required for Maximal Efficacy.
Bustinduy AL; Waterhouse D; de Sousa-Figueiredo JC; Roberts SA; Atuhaire A; Van Dam GJ; Corstjens PLAM; Scott JT; Stanton MC; Kabatereine NB
2016
mBio
A call to strengthen the global strategy against schistosomiasis and soil-transmitted helminthiasis: the time is now.
Lo NC; Addiss DG; Hotez PJ; King CH; Stothard JR; Evans DS; Colley DG; Lin W; Coulibaly JT; Bustinduy AL
2016
The Lancet infectious diseases
A centenary of Robert T. Leiper's lasting legacy on schistosomiasis and a COUNTDOWN on control of neglected tropical diseases.
Stothard JR; Kabatereine NB; Archer J; Al-Shehri H; Tchuem-Tchuenté LA; Gyapong M; Bustinduy AL
2016
Parasitology
Point-of-Care Ultrasound Assessment of Tropical Infectious Diseases--A Review of Applications and Perspectives.
Bélard S; Tamarozzi F; Bustinduy AL; Wallrauch C; Grobusch MP; Kuhn W; Brunetti E; Joekes E; Heller T
2015
The American journal of tropical medicine and hygiene
HIV and schistosomiasis coinfection in African children
Bustinduy A; King CH; Scott J; Sousa-Figueiredo JC; Betson M; Stothard JR
2015
Lancet Infect Dis
Age-Stratified Profiles of Serum IL-6, IL-10, and TNF-α Cytokines Among Kenyan Children with Schistosoma haematobium, Plasmodium falciparum, and Other Chronic Parasitic Co-Infections.
Bustinduy AL; Sutherland LJ; Chang-Cojulun A; Malhotra I; DuVall AS; Fairley JK; Mungai PL; Muchiri EM; Mutuku FM; Kitron U
2015
The American journal of tropical medicine and hygiene
Anemia Among Children Exposed to Polyparasitism in Coastal Kenya.
Chang Cojulun A; Bustinduy AL; Sutherland LJ; Mungai PL; Mutuku F; Muchiri E; Kitron U; King CH
2015
The American journal of tropical medicine and hygiene
Cross-sectional study of the burden of vector-borne and soil-transmitted polyparasitism in rural communities of Coast Province, Kenya.
Bisanzio D; Mutuku F; Bustinduy AL; Mungai PL; Muchiri EM; King CH; Kitron U
2014
PLoS neglected tropical diseases
HIV and schistosomiasis co-infection in African children.
Bustinduy A; King C; Scott J; Appleton S; Sousa-Figueiredo JC; Betson M; Stothard JR
2014
The Lancet infectious diseases
Endomyocardial fibrosis (EMF) in a Ugandan child with advanced hepatosplenic schistosomiasis: coincidence or connection?
Bustinduy AL; Luzinda K; Mpoya S; Gothard P; Stone N; Wright S; Stothard JR
2014
The American journal of tropical medicine and hygiene
Human schistosomiasis.
Colley DG; Bustinduy AL; Secor WE; King CH
2014
Lancet
Development of a specimen-sparing multichannel bead assay to detect antiparasite IgG4 for the diagnosis of Schistosoma and Wuchereria infections on the coast of Kenya.
DuVall AS; Fairley JK; Sutherland L; Bustinduy AL; Mungai PL; Muchiri EM; Malhotra I; Kitron U; King CH
2014
The American journal of tropical medicine and hygiene
Diagnostics for schistosomiasis in Africa and Arabia: a review of present options in control and future needs for elimination.
Stothard JR; Stanton MC; Bustinduy AL; Sousa-Figueiredo JC; Van Dam GJ; Betson M; Waterhouse D; Ward S; Allan F; Hassan AA
2014
Parasitology
Impact of polyparasitic infections on anemia and undernutrition among Kenyan children living in a Schistosoma haematobium-endemic area.
Bustinduy AL; Parraga IM; Thomas CL; Mungai PL; Mutuku F; Muchiri EM; Kitron U; King CH
2013
The American journal of tropical medicine and hygiene
Fecal occult blood and fecal calprotectin as point-of-care markers of intestinal morbidity in Ugandan children with Schistosoma mansoni infection.
Bustinduy AL; Sousa-Figueiredo JC; Adriko M; Betson M; Fenwick A; Kabatereine N; Stothard JR
2013
PLoS neglected tropical diseases
Schistosomiasis in African infants and preschool children: let them now be treated!
Stothard JR; Sousa-Figueiredo JC; Betson M; Bustinduy A; Reinhard-Rupp J
2013
Trends in parasitology
Evaluation of the health-related quality of life of children in Schistosoma haematobium-endemic communities in Kenya: a cross-sectional study.
Terer CC; Bustinduy AL; Magtanong RV; Muhoho N; Mungai PL; Muchiri EM; Kitron U; King CH; Mutuku FM
2013
PLoS neglected tropical diseases
Measuring fitness of Kenyan children with polyparasitic infections using the 20-meter shuttle run test as a morbidity metric.
Bustinduy AL; Thomas CL; Fiutem JJ; Parraga IM; Mungai PL; Muchiri EM; Mutuku F; Kitron U; King CH
2011
PLoS neglected tropical diseases
Impact of drought on the spatial pattern of transmission of Schistosoma haematobium in coastal Kenya.
Mutuku FM; King CH; Bustinduy AL; Mungai PL; Muchiri EM; Kitron U
2011
The American journal of tropical medicine and hygiene
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