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Dr Amaya Bustinduy

MD MPH PhD FRCPCH

Associate Professor
in Tropical Paediatrics

Room
358

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Tel.
+44-020-79272642

Amaya trained in paediatrics and infectious diseases in the US and started working on helminthic infections, mainly schistosomiasis, and their impact on child health in Coastal Kenya in 2009. She is foremost a field clinical epidemiologist and has investigated a broad range of disease manifestations in children related to parasitic diseases, in particular neglected tropical diseases (NTD) that include anaemia, malnutrition, decreased physical performance, decreased quality of life, advanced hepatosplenic disease with a special interest in developing and validating diagnostic and morbidity metric tools at the point-of-care. Other work has included profiling pro-inflammatory cytokines in schistosomiasis and drug (praziquantel) efficacy, particularly in young children.

After moving to the UK, she worked with the Liverpool of Tropical Medicine in Lake Albert Uganda testing novel morbidity point-of-care tests and the first PK/PD study of praziquantel in children. Results of that study are bound to change dosing recommendations for children living with schistosomiasis. Currently she is developing a community-based diagnostic strategy for female genital schistosomiasis. 

She is currently one of the Department Research Degree Coordinators (DRDC).

 

Affiliations

Faculty of Infectious and Tropical Diseases
Department of Clinical Research

Centres

Maternal, Adolescent, Reproductive & Child Health (MARCH)

Teaching

Amaya has been involved in teaching at the East African DTM&H since 2013 and is now the deputy director of the course since 2016. She teaches regularly at the Liverpool (LSTM) and London DTM&H and NDTM&H.

She currently supervises PhD and MSc students at LSHTM, and co-supervises students at LSTM from the MSc in Global Health and Tropical Paediatrics.

Research

  • Female genital schistosomiasis-new diagnostics at a community level
  • Clinical trials involving Pk/PD of antiparasitic drugs in children
  • Point-of-care diagnostics for schistosomiasis (infection and morbidity)
  • HIV-schistosomiasis and other helminthic co-infection and their impact on child health
  • Preschool schistosomiasis and integration of treatment into the Integrated management of childhood illnesses (IMCI)
  • Environmental enteropathy in relation to helminthic diseases
Research Area
Child health
Clinical trials
Diagnostics
Helminths
Parasites
Adolescent health
Global Health
Medicines
Pharmacokinetics
Discipline
Epidemiology
Medicine
Nutrition
Operational research
Parasitology
Pharmacology
Disease and Health Conditions
Infectious disease
Malnutrition
Lymphatic filariasis
Neglected Tropical Diseases (NTDs)
Schistosomiasis
Country
Kenya
Uganda
Zambia

Selected Publications

One hundred years of neglect in paediatric schistosomiasis.
Bustinduy, A.L. ; Wright, S. ; Joekes, E.C. ; Kabatereine, N.B. ; Reinhard-Rupp, J. ; King, C.H. ; Stothard, J.R. ;
Parasitology
Population Pharmacokinetics and Pharmacodynamics of Praziquantel in Ugandan Children with Intestinal Schistosomiasis: Higher Dosages Are Required for Maximal Efficacy.
Bustinduy, A.L. ; Waterhouse, D. ; de Sousa-Figueiredo, J.C. ; Roberts, S.A. ; Atuhaire, A. ; Van Dam, G.J. ; Corstjens, P.L. ; Scott, J.T. ; Stanton, M.C. ; Kabatereine, N.B. ; Ward, S. ; Hope, W.W. ; Stothard, J.R. ;
MBio
Expanding Praziquantel (PZQ) Access beyond Mass Drug Administration Programs: Paving a Way Forward for a Pediatric PZQ Formulation for Schistosomiasis.
Bustinduy, A.L. ; Friedman, J.F. ; Kjetland, E.F. ; Ezeamama, A.E. ; Kabatereine, N.B. ; Stothard, J.R. ; King, C.H. ;
PLoS Negl Trop Dis
Human schistosomiasis.
Colley, D.G. ; Bustinduy, A.L. ; Secor, W.E. ; King, C.H. ;
Lancet
HIV and schistosomiasis co-infection in African children.
Bustinduy, A. ; King, C. ; Scott, J. ; Appleton, S. ; Sousa-Figueiredo, J.C. ; Betson, M. ; Stothard, J.R. ;
Lancet Infect Dis
Impact of polyparasitic infections on anemia and undernutrition among Kenyan children living in a Schistosoma haematobium-endemic area.
Bustinduy, A.L. ; Parraga, I.M. ; Thomas, C.L. ; Mungai, P.L. ; Mutuku, F. ; Muchiri, E.M. ; Kitron, U. ; King, C.H. ;
Am J Trop Med Hyg
Fecal occult blood and fecal calprotectin as point-of-care markers of intestinal morbidity in Ugandan children with Schistosoma mansoni infection.
Bustinduy, A.L. ; Sousa-Figueiredo, J.C. ; Adriko, M. ; Betson, M. ; Fenwick, A. ; Kabatereine, N. ; Stothard, J.R. ;
PLoS Negl Trop Dis
Measuring fitness of Kenyan children with polyparasitic infections using the 20-meter shuttle run test as a morbidity metric.
Bustinduy, A.L. ; Thomas, C.L. ; Fiutem, J.J. ; Parraga, I.M. ; Mungai, P.L. ; Muchiri, E.M. ; Mutuku, F. ; Kitron, U. ; King, C.H. ;
PLoS Negl Trop Dis
See all Dr Amaya Bustinduy's Publications