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TB-drug resistance: impact of pre-clinical resistance mutations

LSHTM staff: Naomi Fuller, Gwen Knight
Funding: LiDO studentship
Collaborators: Tim McHugh (UCL)
Project duration: 2020 - 2023

Bacteriophage - generalised transduction modelling

LSHTM staff: Quentin Leclerc, Gwen Knight
Funding: MRC LID studentship
Collaborators: Jodi Lindsay (St George's)
Project duration: 2018 - 2022

Is transmission of drug-resistant Mycobacterium tuberculosis increasing or decreasing?

LSHTM staff: Finn McQuaid, Rein Houben, Gwen Knight, Richard White
Collaborators: Anna Dean, Matteo Zignol (WHO), Ted Cohen (Yale)

The risk of multidrug or rifampicin-resistance in men versus women with TB

LSHTM staff: Finn McQuaid, Katherine Horton, Gwen Knight, Richard White
Collaborators: Anna Dean (WHO)

Combating MRSA; increasing our understanding of transmission success will lead to better control of MRSA

LSHTM staff: Gwen Knight, Anneke de Vos
Funding: JPIAMR EU
Collaborators: ERASMUS Netherlands
Project duration: 2017 - 2020

The dynamics of drug resistance within hospital populations of Gram-negative bacteria

LSHTM staff: Gwen Knight, Graham Medley
Funding: MRC
Collaborators: Imperial College London, Uppsala University
Project duration: 2017 - 2021

Estimating Vaccine-Avertible Antibiotic Use

Estimating the extent to which vaccines can be used to reduce antibiotic consumption in the community and in healthcare settings, to better account for the value of vaccination programmes.

LSHTM staff: Nick Davies, Mark Jit
Funding: WHO
Collaborators: WHO
Project duration: 2020 - 2020

The Economic and Societal Burden of Antibiotic Resistance

Estimating the incremental impact of antibiotic resistance globally, through information retrieval and evidence synthesis methods.

LSHTM staff: Nichola Naylor, Mark Jit
Funding: WHO
Collaborators: WHO
Project duration: 2020 - 2020

Evaluating the impact of antibiotic resistance-related interventions from a One Health perspective

Evaluating the potential impact of interventions to reduce antimicrobial use in livestock on human antimicrobial resistance and drug-resistant infections, with a focus on how to evaluate these from a One Health Economics perspective. An evaluation framework and toolkit are being developed as part of this project.

LSHTM staff: Jo Lines, Jeff Waage, Nichola Naylor, Gwen Knight, Maria Bernardez
Funding: CGIAR
Collaborators: International Livestock Research Institute (ILRI)
Project duration: 2019 - 2021