About us

Who we are

Antimicrobial Resistance (AMR) is a threat to life and healthcare globally.

The Antimicrobial Resistance Centre at the London School of Hygiene and Tropical Medicine (LSHTM) operates as a centre of excellence in AMR research. Bringing together researchers from a unique breadth of disciplines across the sciences and humanities, the Centre is known for its high quality disciplinary and interdisciplinary work to meet the complex challenge of AMR.

AMR Centre members have expertise in addressing drug-resistant infections along the whole research pipeline, including basic biology, genomics, pharmacology, clinical research, epidemiology, policy research, social sciences and modelling.

Our expertise, established over decades of world-leading research in infectious diseases around the globe, lies in descriptive, experimental and translational research to understand and respond to AMR.

What we do

The Centre has unrivalled reach across scientists, policy makers and practitioners around the globe, with current AMR research in 30 countries. In our research we aim to:

  • Describe where, how and why AMR is a problem
  • Develop, model, evaluate and translate innovative solutions to reduce the threat of AMR

Within LSHTM, there is a strong emphasis on the One Health paradigm, integrating research on human, animal and ecosystem health. This is crucial for tackling AMR, given that transmission and spread occurs through the movement of both microbes and antimicrobials between humans, animals and the environment.

As part of our commitment to world-leading research, we help to share and expand knowledge and foster new collaborations by: hosting seminars with speakers at the cutting-edge of their fields; organising and collaborating in events at LSHTM and across the world; actively engaging in debates on policy; fortnightly academic-led newsletter and twitter feed.

LSHTM is also a host institution to cohorts of Fleming Fund Fellows, a programme funded by the UK Department of Health and Social Care, which aims to help fellows from around the world to develop the skills required to combat the global threat of antibiotic resistance. 

Research Pillars
Biological and Pharmacological Sciences

The Biological and Pharmacological Sciences pillar covers a wide range of areas; at its core we work directly with microbes in laboratory conditions to learn more about the mechanisms of resistance, and above all design effective new antimicrobials to fight disease.

Pillar Head: John Dallow

Clinical and Veterinary Sciences

Observations in clinical and veterinary medicine are perhaps the most obvious manifestations of antimicrobial resistance. What constitutes “inappropriate use” or “overuse” of antimicrobials in various contexts? How can this be reduced or eliminated? What constitutes “appropriate” or “rational” antimicrobial use, and how can this be promoted?

Pillar Head: Chris Pinto

Epidemiology and Modelling

Mathematical models are simplified descriptions of the key mechanisms underlying various processes and phenomena. Whereas the output of epidemiological models is normally the incidence or prevalence of disease or resistance, micro-economic model outputs focus on cost and cost-effectiveness of infection control and macro-economic models concern the full societal financial impact of resistance or control strategies.

Pillar Head: Alfred Ngwa

Economic, Social and Political Sciences

At LSHTM, the economic, social and political sciences are a crucial component of our research into antimicrobial resistance.  Our researchers apply these disciplines in order to explore the personal, social, and societal worlds of AMR, both in Low and Middle Income countries, and in the UK.

Pillar Head: Meenakshi Gautham

Humanities and Environmental Sciences

There is a growing awareness that holistic and context-aware solutions are required in response to the technical and policy problems posed by AMR. However, there is little awareness of how to factor contextual components into policy processes. History, literary and critical studies, geography and environmental sciences possess key technical and methodological skills in discursive, spatial and ecological analysis of crucial contextual dimensions of anti-microbial resistance.

Pillar Head: Jacqueline Knee

Centre Leadership

Kat Holt

Co-Director of the AMR Centre

Professor of Microbial Genomics

Gwen Knight

Co-Director of the AMR Centre

Associate Professor

Sherif Abouelhadid

Head of Biological and Pharmacological Sciences at the AMR Centre

Charlene Rodrigues

Head of Clinical and Veterinary Sciences at the AMR Centre

Portrait of Alfred Ngwa, Head of Epidemiology and Modelling at the AMR Centre

Alfred Ngwa

Head of Epidemiology and Modelling at the AMR Centre

Meenakshi Gautham

Head of Economic, Social and Political Sciences at the AMR Centre

Jacqueline Knee

Head of Humanities and Environmental Sciences at the AMR Centre

Saffiatou Darboe

Saffiatou Darboe

PhD Student Representative for the AMR Centre

PhD Student at the MRC Unit The Gambia at LSHTM

Steering Committee

AMR researchers at LSHTM