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Research Pillars

AMR Centre Research Pillars

The Antimicrobial Resistance Centre is divided into five Pillars, each representing research areas critical to understanding and combatting AMR. 

See more information below about the work and themes each Pillar is involved with.

Biological and Pharmacological Sciences

The Biological and Pharmacological Sciences pillar covers a wide range of areas; at its core we work directly with microbes in laboratory conditions to learn more about the mechanisms of resistance, and above all design effective new antimicrobials to fight disease.

Pillar Head: Sherif Abouelhadid

Clinical and Veterinary Sciences

Observations in clinical and veterinary medicine are perhaps the most obvious manifestations of antimicrobial resistance. What constitutes “inappropriate use” or “overuse” of antimicrobials in various contexts? How can this be reduced or eliminated? What constitutes “appropriate” or “rational” antimicrobial use, and how can this be promoted?

Pillar Head: Charlene Rodrigues

Epidemiology and Modelling

Mathematical models are simplified descriptions of the key mechanisms underlying various processes and phenomena. Whereas the output of epidemiological models is normally the incidence or prevalence of disease or resistance, micro-economic model outputs focus on cost and cost-effectiveness of infection control and macro-economic models concern the full societal financial impact of resistance or control strategies.

Pillar Head: Alfred Ngwa

Economic, Social and Political Sciences

At LSHTM, the economic, social and political sciences are a crucial component of our research into antimicrobial resistance.  Our researchers apply these disciplines in order to explore the personal, social, and societal worlds of AMR, both in Low and Middle Income countries, and in the UK.

Pillar Head: Meenakshi Gautham

Humanities and Environmental Sciences

There is a growing awareness that holistic and context-aware solutions are required in response to the technical and policy problems posed by AMR. However, there is little awareness of how to factor contextual components into policy processes. History, literary and critical studies, geography and environmental sciences possess key technical and methodological skills in discursive, spatial and ecological analysis of crucial contextual dimensions of anti-microbial resistance.

Pillar Head: Jacqueline Knee