series event

28th Bradford Hill Memorial Lecture

Countering the HIV epidemic: statistical issues in treatment evaluation and policy

Sir Bradford Hill

In conjunction with the Royal Statistical Society, the London School of Hygiene & Tropical Medicine is pleased to host Dr Michael Hughes who will deliver the 2019 Bradford Hill Memorial Lecture:

There has been remarkable progress in HIV treatment, changing HIV infection from being a more immediately life-threatening disease to a chronic disease.  Numerous treatments have been evaluated in a long sequence of non-inferiority clinical trials using a surrogate endpoint, and complexities have arisen at the interface of treatment and prevention.  Key policy questions included when during the course of the disease to start treatment, and the extent to which treatment recommendations can be population-based versus personalized.  Dr Hughes will describe some of the interesting statistical issues that have been addressed in advancing treatment for HIV infection.

Dr Michael Hughes is Professor of Biostatistics at the Harvard T.H. Chan School of Public Health, where he is also Director of the Center for Biostatistics in AIDS Research. He trained at the University of Cambridge and the London School of Hygiene and Tropical Medicine (LSHTM) and then completed his PhD while working at the Royal Free Hospital School of Medicine and LSHTM.  Dr. Hughes is Principal Investigator of the Statistical and Data Management Center for the United States NIH-funded AIDS Clinical Trials Group, the largest HIV treatment trials network in world.  He is an elected Fellow of the American Statistical Association and Statistical Editor of the Journal of Infectious Diseases.  Dr. Hughes' biostatistical research interests are focused on statistical issues in the design and analysis of infectious diseases research studies.  Particular interests include surrogate endpoint validation, use of biomarkers in diagnosis and treatment policymaking, dynamic and sequential trial designs, competing risks methods, and design issues in clustered study designs. 


The lecture will be followed by a reception in the South Courtyard Cafe.


This lecture will be livestreamed/recorded - accessible to both internal and external audience.

Watch this session live


2019 is the 50th anniversary of the MSc Medical Statistics. Visit the event page to find out more about the anniversary Symposium:


Symposium to Celebrate 50 Years of the MSc Medical Statistics


Free. First come, first served.