Research projects listing

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IMPRINT: IMmunising PRegnant women and INfants network

IMPRINT is a network focusing on maternal and neonatal immunization, funded by the UK’s Global Challenges Research Fund (GCRF) which supports challenge-led interdisciplinary research and aims to strengthen capacity for research and innovation within the UK and in developing countries. IMPRINT aims to build a sustainable network of stakeholders from basic science, immunology, vaccinology, social sciences, industry, public health and national and international policy makers, to tackle the challenges in the best use of vaccines in pregnancy and in newborns, and in the long term to improve maternal and newborn health. 

A Dose Reduction Immunobridging and Safety Study of Two HPV Vaccines in Tanzanian Girls (DoRIS)

A Dose Reduction Immunobridging and Safety Study of Two HPV Vaccines in Tanzanian Girls (DoRIS) trial evaluates immunogenicity and safety of one dose of HPV vaccine in Tanzania. The objective of this trial is to demonstrate non-inferiority of immune responses with 1 dose of HPV vaccine compared with the recommended 2 or 3 doses of the same vaccine by evaluating HPV 16/18-specific seropositivity, antibody avidity and memory B cell responses at M36. 

Evaluating the impact of Pneumococcal Conjugate Vaccine (PCV10) in Kenya

The Pneumococcal Conjugate Vaccine Impact Study (PCVIS) is one of the first population-level studies to look at the impact of a pneumococcal conjugate vaccine (PCV10) programme on childhood pneumonia and pneumococcal disease protection in a low- or middle-income country. It is a partnership between the KEMRI-Wellcome Trust Research Programme, the London School of Hygiene & Tropical Medicine, GAVI and the Government of Kenya.


Ebola vaccine projects – EBOVAC1EBOVAC2EBOVAC3EBODAC and EBOMAN – are a series of trials and associated projects which aim to assess a novel two-dose preventive vaccine regimen against Ebola Virus Disease (EVD). In a two-dose vaccine regimen, individuals are given a first dose to prime the immune system, and then a second dose which is intended to enhance the immune response and increase the duration of the response.



SYSVAC is a database of systematic reviews on vaccines and immunisation. These have been collated from other databases, so as to provide a more streamlined resource.