Publications

Lipophilic conformationally constrained spiro carbocyclic 2,6-diketopiperazine-1-acetohydroxamic acid analogues as trypanocidal and leishmanicidal agents: An extended SAR study.

Zoidis, G; Tsotinis, A; Tsatsaroni, A; TAYLOR, MC; KELLY, JM; Efstathiou, A; Smirlis, D; Fytas, G;

2017

Chemical biology & drug design, (2017).91 2 10.1111/cbdd.13088.

Comparative Genomic Analysis and In Vivo Modeling of Streptococcus pneumoniae ST3081 and ST618 Isolates Reveal Key Genetic and Phenotypic Differences Contributing to Clonal Replacement of Serotype 1 in The Gambia.

Bricio-Moreno, L; EBRUKE, C; Chaguza, C; Cornick, J; Kwambana-Adams, B; Yang, M; MACKENZIE, G; WREN, BW; Everett, D; ANTONIO, M; Kadioglu, A;

2017

The Journal of infectious diseases, (2017).216 10 10.1093/infdis/jix472.

Whole genome sequencing of ESBL-producing Escherichia coli isolated from patients, farm waste and canals in Thailand.

Runcharoen, C; Raven, KE; Reuter, S; Kallonen, T; Paksanont, S; Thammachote, J; Anun, S; Blane, B; Parkhill, J; PEACOCK, SJ; Chantratita, N;

2017

Genome medicine, (2017).9 1 10.1186/s13073-017-0471-8.

A potent series targeting the malarial cGMP-dependent protein kinase clears infection and blocks transmission.

BAKER, DA; STEWART, LB; Large, JM; Bowyer, PW; Ansell, KH; Jiménez-Díaz, MB; El Bakkouri, M; Birchall, K; Dechering, KJ; Bouloc, NS; Coombs, PJ; Whalley, D; Harding, DJ; Smiljanic-Hurley, E; Wheldon, MC; WALKER, EM; DESSENS, JT; Lafuente, MJ; Sanz, LM; Gamo, F-J; Ferrer, SB; Hui, R; Bousema, T; Angulo-Barturén, I; Merritt, AT; ... Osborne, SA.

2017

Nature communications, (2017).8 1 10.1038/s41467-017-00572-x.

Evolution of mobile genetic element composition in an epidemic methicillin-resistant Staphylococcus aureus: temporal changes correlated with frequent loss and gain events.

Jamrozy, D; COLL, F; Mather, AE; Harris, SR; Harrison, EM; MacGowan, A; Karas, A; Elston, T; Estée Török, M; Parkhill, J; PEACOCK, SJ;

2017

BMC genomics, (2017).18 1 10.1186/s12864-017-4065-z.

Infection, contagion and causality in Colonial Britain: the 1889-90 influenza pandemic and the British Medical Journal.

KOUSOULIS, AA; Tsoucalas, G;

2017

Le infezioni in medicina, (2017).25 3

Randomised controlled trial of two sequential artemisinin-based combination therapy regimens to treat uncomplicated falciparum malaria in African children: a protocol to investigate safety, efficacy and adherence.

Schallig, HD; Tinto, H; Sawa, P; KAUR, H; Duparc, S; Ishengoma, DS; Magnussen, P; Alifrangis, M; SUTHERLAND, CJ;

2017

BMJ global health, (2017).2 3 10.1136/bmjgh-2017-000371.

Comparison of the susceptibility of Plasmodium knowlesi and Plasmodium falciparum to antimalarial agents.

VAN SCHALKWYK, DA; MOON, RW; Blasco, B; SUTHERLAND, CJ;

2017

The Journal of antimicrobial chemotherapy, (2017).72 11 10.1093/jac/dkx279.

Genome-wide profiling of humoral immunity and pathogen genes under selection identifies immune evasion tactics of Chlamydia trachomatis during ocular infection.

PICKERING, H; Teng, A; Faal, N; Joof, H; Makalo, P; Cassama, E; Nabicassa, M; LAST, AR; BURR, SE; Rowland-Jones, SL; THOMSON, NR; ROBERTS, CH; MABEY, DC W; BAILEY, RL; Hayward, RD; De la Maza, LM; HOLLAND, MJ;

2017

Scientific reports, (2017).7 1 10.1038/s41598-017-09193-2.

Discovery and Optimization of 5-Amino-1,2,3-triazole-4-carboxamide Series against Trypanosoma cruzi.

Brand, S; Ko, EJ; Viayna, E; Thompson, S; Spinks, D; Thomas, M; Sandberg, L; FRANCISCO, AF; JAYAWARDHANA, S; SMITH, VC; Jansen, C; De Rycker, M; Thomas, J; MacLean, L; Osuna-Cabello, M; Riley, J; Scullion, P; Stojanovski, L; Simeons, FR C; Epemolu, O; Shishikura, Y; Crouch, SD; Bakshi, TS; Nixon, CJ; Reid, IH; ... Gilbert, IH.

2017

Journal of medicinal chemistry, (2017).60 17 10.1021/acs.jmedchem.7b00463.