Mycoplasma genitalium: antimicrobial resistance and implications for management?
Mycoplasma genitalium is an established cause of urethritis and cervicitis and has recently been shown to increase the risk of pelvic inflammatory disease, spontaneous abortion and pre-term delivery. M.genitalium has displayed a marked propensity to develop antimicrobial resistance (AMR) to recommended first and second line antimicrobials.
New classes of antimicrobials are urgently needed, but in the meantime we need to develop innovative treatment strategies that limit the use of azithromycin and use combined diagnostic-resistance assays to individualize antimicrobial therapy. Data will be presented on the repurposing of old drugs and novel approaches to achieve high level cure.