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Dr Richard Stabler

PhD

Associate Professor
in Molecular Bacteriology

Room
Room 383

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Tel.
44 207 927 2824

Fax.
44 207 637 4314

PhD thesis - Characterisation of a novel pore-forming cytolysin from Mycobacterium tuberculosis and other bacterial patghogens.

Work History

I undertook my Ph.D. while working as a research assistant at St Bartholomews Hospital and then LSHTM. After completing the Ph.D. I took a post-doc position at the Bacterial Microarray Group at St. Georges Hospital (BuG@S). I was involved in design, construction, experimental design, application and data analysis on several bacterial projects.

I returned to LSHTM for my second Ph.D position that was primarily to design a microarray that could be used to monitor gene flux of virulence factors. The Active Surveillance of Pathogens (ASP) microarray has been successfully produced and has been used to identify novel virulence determinants in Shigella sonnei and Chromobacterium violaceum.

Affiliations

Department of Pathogen Molecular Biology
Faculty of Infectious and Tropical Diseases

Centres

Antimicrobial Resistance Centre

Teaching

Course Director for the MSc Medicial Microbiology

Module Organiser for Core Bacteriology and Clinical Bacteriology

Lecturer on the MSc Medicial Microbiology

Lecturer on the MSc Molecular Biology of Infectious Diseases

Lecturer on the MSc Control of Infectious Diseases

Research

Research interests include

i) Clostridium difficile: molecular epidemiology and emergence of hypervirulent isolates.

ii) Methicillin resistant Staphylococcus areus: molecular epidemiology and drug resistance

iii) Campylobacter jejuni: molecular epidemiology and identification of source specific markers.

iv) Escherichia coli K1: Analysis of interaction with and role of gut flora in disease process.

v) Development of drug resistance in Acinetobacter baumannii

vi) Development of drug resistance in Neisseria gonorrhoea

Research Area
Bacteria
Diagnostics
Discipline
Genetic epidemiology
Genomics
Molecular epidemiology
Bacteriology
Genetics
Microbiology
Molecular biology
Pathology
Disease and Health Conditions
Diarrhoeal diseases
Infectious disease
Country
Australia
Brazil
United Kingdom
India
Netherlands
Singapore
United States
Vietnam
Region
East Asia & Pacific (all income levels)
Euro area
Latin America & Caribbean (all income levels)
North America

Selected Publications

The induction and identification of novel Colistin resistance mutations in Acinetobacter baumannii and their implications.
Thi Khanh Nhu, N. ; Riordan, D.W. ; Do Hoang Nhu, T. ; Thanh, D.P. ; Thwaites, G. ; Huong Lan, N.P. ; Wren, B.W. ; Baker, S. ; Stabler, R.A. ;
Sci Rep
The Genotoxin Colibactin is a Determinant of Virulence in Escherichia coli K1 Experimental Neonatal Systemic Infection.
McCarthy, A.J. ; Martin, P. ; Cloup, E. ; Stabler, R. ; Oswald, E. ; Taylor, P.W. ;
Infect Immun
Clonal variation in high- and low-level phenotypic and genotypic mupirocin resistance of MRSA isolates in south-east London.
Hughes, J.; Stabler, R.; Gaunt, M.; Karadag, T.; Desai, N.; Betley, J.; Ioannou, A.; Aryee, A.; Hearn, P.; Marbach, H.; Patel, A.; Otter, J.A.; Edgeworth, J.D.; Tosas Auguet, O.;
J Antimicrob Chemother
Staphylococcal Phenotypes Induced by Naturally Occurring and Synthetic Membrane-Interactive Polyphenolic β-Lactam Resistance Modifiers.
Palacios, L. ; Rosado, H. ; Micol, V. ; Rosato, A.E. ; Bernal, P. ; Arroyo, R. ; Grounds, H. ; Anderson, J.C. ; Stabler, R.A. ; Taylor, P.W. ;
PLoS One
Altered innate defenses in the neonatal gastrointestinal tract in response to colonization by neuropathogenic Escherichia coli.
Birchenough, G.M.; Johansson, M.E.; Stabler, R.A.; Dalgakiran, F.; Hansson, G.C.; Wren, B.W.; Luzio, J.P.; Taylor, P.W.;
Infect Immun
Macro and Micro Diversity of Clostridium difficile Isolates from Diverse Sources and Geographical Locations
Stabler, R.A.; Dawson, L.F.; Valiente, E.; Cairns, M.D.; Martin, M.J.; Donahue, E.H.; Riley, T.V.; Songer, J.G.; Kuijper, E.J.; Dingle, K.E.; Wren, B.W.;
PLoS One
See all Dr Richard Stabler's Publications