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Professor Grant Mackenzie

Professor

United Kingdom

Dr Mackenzie is a clinical epidemiologist/paediatrician with a research focus to link clinical/field studies with laboratory investigations to answer biological and public health question relevant to infectious disease and child health in low-income settings. He trained clinically in Australia and completed his PhD there before undertaking additional training and experience in HIV care in London and Kenya. He has been based in West Africa at the Basse Field Station of the Medical Research Council Unit The Gambia at LSHTM since 2008.

Affiliations

Department of Disease Control
Faculty of Infectious and Tropical Diseases

Teaching

Dr Mackenzie has led the academic environment at the MRCG at LSHTM Basse Field Station since 2008, leading the regular Journal Club and Scientific Seminars and supporting others to gain experience coordinating these activities. He has supervised two PhD students to completion. He has supervised four Master's students and summer projects for five LSHTM Master's students.

Dr Mackenzie is a member of the team delivering the LSHTM distance learning programme for Control of Communicable Diseases, marking exams and assignments, formulating new questions and supporting students on the Moodle forum. He also lectures in the LSHTM short course on Introductory Epidemiology and Biostatistics held each year in The Gambia.

Research

Dr Mackenzie has co-ordinated surveillance for pneumococcal disease and carriage evaluating the clinical and economic effectiveness of the introduction of pneumococcal conjugate vaccine in The Gambia. He is currently conducting a large cluster-randomised trial of different pneumococcal vaccine schedules.

His other work has investigated long-term outcomes after childhood hospital admissions and the critical role of malnutrition, epidemiology, aetiology and risk factors for childhood pneumonia, the changing performance over time of IMCI criteria for pneumonia, causes of serious bacterial illness and interactions with malaria epidemiology, and the epidemiology of acute respiratory viral disease in children.

Selected Publications

Prognosis of clinical pneumonia in undernourished children in rural Gambia.
Isa, YS; Carelus, M; Silber, I; Salaudeen, R; Sarwar, G; Olatunji, YA; Hossain, I; OSEI, I; Lobga, G; Adeshola, B; Barjo, O; Drammeh, MM; D'ALESSANDRO, U; Hibberd, PL; MACKENZIE, GA; Valim, C;
2026
Pneumonia (Nathan)
Molecular characterisation of a
<i>Klebsiella pneumoniae</i>
neonatal sepsis outbreak in a rural Gambian hospital: a retrospective genomic epidemiology investigation
FOSTER-NYARKO, E; Bah, A; Adefila, WO; OSEI, I; Barjo, O; Salaudeen, R; Able-Thomas, S; Jammeh, M; Nyassi, A; Odih, EE; HOLT, KE; Sesay, AK; MACKENZIE, G;
2026
openRxiv
Serotype-specific pneumococcal invasiveness: a global meta-analysis of paired estimates of disease incidence and carriage prevalence.
GALLAGHER, KE; Odiwour, F; BOTTOMLEY, C; Ojal, J; Adamu, A; Muthumbi, E; Kagucia, EW; Hammitt, LL; Massora, S; Sigaúque, B; Chaúque, A; Vilanculos, L; Verani, JR; Da Gloria Carvalho, M; Von Gottberg, A; Kleynhans, J; Madhi, SA; Olwagen, CP; MACKENZIE, G; Salaudeen, R; Gierke, R; Kobayashi, M; Pelton, S; Yildirim, I; Thomas, S; ... SCOTT, JA G.
2026
The Lancet Microbe
7-year trend of timely hepatitis B birth dose vaccination coverage in The Gambia: a retrospective, population-based analysis.
NDOW, G; CHAM, I; Bangura, R; Drammeh, S; De Bezenac, C; Golam S, S; Ezeani, E; Gomez, P; Badjie, S; Fofana, S; Bittaye, M; MACKENZIE, G; Randon-Furling, J; D'ALESSANDRO, U; Shimakawa, Y; Lemoine, M;
2026
The Lancet. Global health
Shea Butter Application to the Umbilical Stump Resulting in Omphalitis and Leclercia adecarboxylata Bacteremia in a Neonate: A Case Report.
Omotosho, MB; Adefila, WO; Yusuf, AO; OSEI, I; WUTOR, BM; Keita, ML; Minteh, M; Barjo, O; Wally, M; Salaudeen, R; MACKENZIE, G;
2025
Case reports in infectious diseases
Brevundimonas vesicularis sepsis in a 2-month-old infant in rural Gambia: a case report.
Molfa, M; Adefila, WO; WUTOR, BM; Keita, M; Olawale, YA; Omotosho, MB; Barjo, O; Salaudeen, R; OSEI, I; Wally, M; MACKENZIE, G;
2025
Journal of medical case reports
Identification of age-group reservoirs for persistent vaccine-type pneumococcal carriage in rural Gambia.
OSEI, I; Mendy, E; VAN ZANDVOORT, K; Jobe, O; Sarwar, G; MOHAMMED, NI; Bruce, J; Barjo, O; Molfa, M; Salaudeen, R; GREENWOOD, B; FLASCHE, S; MACKENZIE, GA;
2025
Pneumonia (Nathan Qld.)
Household Molecular Epidemiology of Streptococcus pyogenes Carriage and Infection in The Gambia.
De Crombrugghe, G; Armitage, EP; KEELEY, AJ; Senghore, E; Camara, F; Jammeh, M; Bittaye, A; Ceesay, H; Ceesay, I; Samateh, B; Manneh, M; Botquin, G; Lakhloufi, D; Delforge, V; Bah, SY; Hall, JN; Schiavolin, L; Turner, CE; MARKS, M; De Silva, TI; Botteaux, A; Smeesters, PR; MRCG StrepA Study Group,;
2025
The Journal of infectious diseases
Effect of the 13-valent pneumococcal conjugate vaccine on pneumococcal carriage in rural Gambia 10 years after its introduction: A population-based cross-sectional study.
OSEI, I; Mendy, E; VAN ZANDVOORT, K; Sarwar, G; NUREDIN, IM; BRUCE, J; Barjo, O; Molfa, M; Salaudeen, R; GREENWOOD, B; FLASCHE, S; MACKENZIE, GA;
2025
Vaccine
Cohort Profile: Basse Health and Demographic Surveillance System, the Gambia.
EZEANI, ES; Gollam, S; MOHAMMED, N; ROCA, A; Hossain, J; Hossain, I; Saine, AK; D'ALESSANDRO, U; MACKENZIE, G;
2025
International journal of epidemiology
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