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Dr Julius Hafalla

Associate Professor

London School of Hygiene and Tropical Medicine
Keppel Street
London
WC1E 7HT
United Kingdom

Tel.
+44 (0) 2079588129
Julius Hafalla obtained his BSc in Molecular Biology and Biotechnology (cum laude) from the University of the Philippines – Diliman. He then worked as a Research Assistant at the Research Institute for Tropical Medicine (Philippines) and as a Fogarty Fellow at the International Health Institute of Brown University (USA). Julius obtained his MSc and PhD in Basic Medical Sciences at New York University (USA), where he investigated the development of T cell responses to malaria liver stage infection. He also did post-doctoral work in parasitology, immunology and pre-clinical vaccine development at New York University.

In 2005, Julius joined the LSHTM as a Royal Society Incoming Fellow to study the regulation of pathogenic responses during blood stage malaria infections, and as a Wellcome Trust Visiting Fellow in Public Health and Tropical Medicine to examine cellular immune responses to malaria in Thailand and Tanzania. In 2008, Julius was awarded a Royal Society University Research Fellowship, which was renewed in 2013. He was appointed as a Senior Lecturer in Immunology in 2013, and an Associate Professor in 2015.

Since 2015, Julius has been facilitating the LSHTM’s external partnerships with institutions in the Philippines and other countries in South East Asia. He is currently a faculty of the Joint PhD Programme in Global Health between LSHTM and Nagasaki University, Japan, and the West African Centre for Cell Biology of Infectious Pathogens, University of Ghana, Legon, Ghana.

Affiliations

Department of Infection Biology
Faculty of Infectious and Tropical Diseases

Centres

Malaria Centre
Vaccine Centre

Teaching

Research Degrees Coordinator: Department of Infection Biology, Department of Disease Control, and MRC Units (Gambia and Uganda)
Module Organiser: Advanced Immunology I (3134) and II (3144)
Deputy Module Organiser: Immunology of Parasitic Infections (3177)
Lecturer: Immunology of Infectious Diseases (3120), Medical Parasitology (3122), Advanced Immunology I (3134) and II (3144), Immunology of Parasitic Infections (3177), Vaccine Immunology (3191), Malaria (3195)
Tutor and MSc Project Supervisor: MSc Immunology for Infectious Diseases, MSc Medical Parasitology, MSc Control of Infectious Diseases
Programme Committee and Exam Board: MSc Immunology for Infectious Diseases, MSc Medical Parasitology

Research

Julius Hafalla's research investigates factors that govern the magnitude, efficiency and long-term maintenance of protective immune responses to infection, focussing on malaria, dengue and tuberculosis. He has an interest in understanding protective and pathological mechanisms involved in these infections. He is involved in infectious disease research in The Philippines and in Ghana.
Research Area
Bacteria
Diagnostics
Disease control
Global Health
Immunisation
Parasites
Protozoa
T-cell immunology
Vaccines
Bacteriology
Bioinformatics
Genomics
Immunoepidemiology
Immunology
Microbiology
Parasitology
Vaccinology
Virology
Disease and Health Conditions
Dengue
Malaria
Schistosomiasis
Tropical diseases
Infectious diseases
Emerging infectious diseases
Vector borne diseases
Country
Brazil
Gambia
Ghana
Indonesia
Philippines
Vietnam
Region
East Asia & Pacific (developing only)
Sub-Saharan Africa (developing only)

Selected Publications

The impact of elevation and population density on dengue incidence and force of infection across the Philippines: Implications for climate-adapted surveillance.
Sy, AK; BIGGS, J; Chowdhury, SK; Quinones, MA; Salazar, FV; JONES-WARNER, W; Ashall, J; Sucaldito, MN L; Cutiongco-de la Paz, E; Capeding, MR Z; Padilla, CD; Villanueva, SY A M; HIBBERD, ML; HAFALLA, JC R;
2026
PLoS neglected tropical diseases
A functional crosstalk between circulating follicular helper 2 T cells and memory B cells drives anti-Plasmodium vivax antibodies.
Salsabila, ZZ; Kochayoo, P; Khunsri, T; Tianpothong, P; Leepiyasakulchai, C; Thawornpan, P; HAFALLA, JC R; Adams, JH; Chootong, P;
2026
PLoS neglected tropical diseases
Evaluating dengue transmission dynamics in an endemic urban setting in Viet Nam: an index-household contact cohort study.
Masdin, L; Ashall, J; Kim Huynh, M; BIGGS, J; PHELAN, J; Shah, S; Thuy Le, L; Bao Nguyen, T; Thai Do, H; Anh Thi Nguyen, H; Thi Thu Nguyen, T; Anh Dang, D; Iwasaki, C; Toizumi, M; Van Loock, M; Herrera-Taracena, G; Vijgen, L; Rasschaert, F; Van Wesenbeeck, L; HAFALLA, JC; BRADY, OJ; Yoshida, L-M; Hué, S; HIBBERD, ML;
2026
The Lancet. Infectious diseases
Integrating forest data and health facility surveys to optimise risk-based malaria surveillance in the Philippines.
Fornace, KM; Reyes, RA; Macalinao, ML M; Lim, J-S; Bareng, AP N; Luchavez, JS; HAFALLA, JC R; Espino, FE J; Matthiopoulos, J; DRAKELEY, CJ;
2025
Frontiers in Public Health
Complete attenuation of Plasmodium falciparum sporozoites by atovaquone-proguanil.
Borrmann, S; Sulyok, Z; Müller, K; Fendel, R; Sulyok, M; Friesen, J; Lalremruata, A; Sandri, TL; Nguyen, TT; Calle, CL; Knoblich, A; Sefried, S; Ibáñez, J; Lorenz, F-R; Heimann, HL; Weller, DM; Steuder, R; Adukpo, S; Granados Bayon, P; Molnár, Z; Esen, M; Metzger, W; James, ER; Ruben, A; Abebe, Y; ... Mordmüller, B.
2025
EMBO molecular medicine
Genetically attenuated parasites show promise as a next-generation malaria vaccine.
HAFALLA, JC R; Borrmann, S; Matuschewski, K;
2025
Trends in parasitology
Whole genome sequencing analysis of Mycobacterium tuberculosis reveals circulating strain types and drug-resistance mutations in the Philippines.
Wang, L; Lim, DR; PHELAN, JE; Reyes, LT; Palparan, AG; Sanchez, MG C; Asuncion, LA A; Tujan, MA A; Medado, IA P; Daga, CM A; Llames, J-HS; Mitarai, S; Murase, Y; Morishige, Y; Ang, CF; Malabad, JC M; Montoya, JC; HAFALLA, JC; CAMPINO, S; HIBBERD, ML; Ama, CG; Basilio, RP; La Paz, EM C-D; CLARK, TG;
2024
Scientific reports
Utilization of novel molecular multiplex methods for the detection and, epidemiological surveillance of dengue virus serotypes and chikungunya virus in Burkina Faso, West Africa.
Gomgnimbou, MK; Belem, LR W; Some, K; Diallo, M; Barro, B; Kaboré, A; HAFALLA, JC R; Sangaré, I;
2024
Molecular biology reports
Could prophylactic antivirals reduce dengue incidence in a high-prevalence endemic area?
Jafari, Y; BRADY, OJ; BIGGS, JR; Lien, LT; Mai, HK; Nguyen, HA T; Van Loock, M; Herrera-Taracena, G; Menten, J; Iwasaki, C; Takegata, M; Kitamura, N; Do Thai, H; Minh, BX; Morita, K; Anh, DD; Clifford, S; PREM, K; HAFALLA, J; EDMUNDS, WJ; Yoshida, LM; HIBBERD, ML; Hué, S;
2024
PLoS neglected tropical diseases
Genomic analysis of Salmonella enterica from Metropolitan Manila abattoirs and markets reveals insights into circulating virulence and antimicrobial resistance genotypes.
Mora, JF B; Meclat, VY B; Calayag, AM B; CAMPINO, S; HAFALLA, JC R; HIBBERD, ML; PHELAN, JE; CLARK, TG; Rivera, WL;
2024
Frontiers in microbiology
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