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Dr Ruth Costello

Assistant Professor

United Kingdom

I am an assistant professor and I use electronic health record data in epidemiology and pharmacoepidemiology studies. Recent work has investigated inequalities in healthcare disruption related to the pandemic and repurposing of drugs to treat COVID-19. I previously worked at the University of Manchester where I used CPRD data in studies in the field of rheumatology. While working in Manchester I completed my PhD by publication, this included 7 studies with the theme of using digital data to investigate the management of rheumatoid arthritis.

Affiliations

Department of Infectious Disease Epidemiology and Dynamics
Faculty of Epidemiology and Population Health

Teaching

I am co-course organise for block 2 - "Introduction to Pharmacovigilance" in the Pharmacoepidemiology and pharmacovigilance short course. I also teach on the extended epidemiology module. 

Selected Publications

Occurrence and persistence of symptoms, diagnoses and prescriptions after community-diagnosed COVID-19: a matched cohort study using the OpenSAFELY platform.
Wing, K; Morton, C; Mahalingasivam, V; COSTELLO, RE; Cowling, T; Lin, L-Y; Inglesby, P; Walker, A; OpenSAFELY Collaborative,; LH&W NCS (or CONVALESCENCE) Collaborative,; Bacon, S; Mehrkar, A; Goldacre, B; EVANS, S; Douglas, I; EGGO, R; TOMLINSON, L; MANSFIELD, KE;
2026
Journal of epidemiology and community health
Winter pressures in general practice in England.
Denholm, RE; PETTIGREW, LM; DAWADI, S; HERRETT, E; COSTELLO, RE; Zou, M; EGGO, RM;
2026
The British journal of general practice : the journal of the Royal College of General Practitioners
Outpatient hospital attendances in people with rheumatoid arthritis during the COVID-19 pandemic and beyond: a cohort study in three nations of the UK.
COSTELLO, RE; Parker, M; Kennedy, J; Brophy, S; Mehrkar, A; Bacon, S; Goldacre, B; MacKenna, B; Evans, D; TOMLINSON, LA; Hollick, RJ; Humphreys, JH; OpenSAFELY Collective, The RHEUMAPS Study Investig,;
2025
Rheumatology (Oxford, England)
The relationship between general practice characteristics, case-mix, and secondary care attendances/admissions before and after the COVID-19 pandemic: Protocol for an OpenSAFELY cohort study.
Zou, M; DAWADI, S; PETTIGREW, LM; EGGO, RM; HERRETT, E; Walker, V; MARKS, M; Sterne, J; Walker, A; Tamborska, A; Gill, J; Macleod, J; FILIPE, J; MAH, H; Bacon, S; Curtis, M; Mehrkar, A; COSTELLO, R; Denholm, R;
2025
Wellcome Open Research
The relationship between general practice characteristics, case-mix, and secondary care attendances/admissions before and after the COVID-19 pandemic: Protocol for an OpenSAFELY cohort study.
Zou, M; DAWADI, S; PETTIGREW, LM; EGGO, RM; HERRETT, E; Walker, V; MARKS, M; Sterne, J; Walker, A; Tamborska, A; Gill, J; Macleod, J; FILIPE, J; MAH, H; Bacon, S; Curtis, M; Mehrkar, A; COSTELLO, R; Denholm, R;
2025
Wellcome Open Research
Long-term kidney outcomes after COVID-19: a matched cohort study using the OpenSAFELY platform.
MAHALINGASIVAM, V; Zheng, B; Wing, K; PARKER, EP K; BHASKARAN, K; Carrero, JJ; Jayacodi, S; Jumbo, E; Miah, T; Gracey, B; TAZARE, J; Santhakumaran, S; Mathur, R; COSTELLO, RE; HERRETT, E; Wen, Q; Hartney, T; DOUGLAS, IJ; Green, A; Fisher, L; Curtis, HJ; Walker, AJ; MacKenna, B; Hulme, WJ; Mehrkar, A; ... TOMLINSON, L.
2025
The Lancet Regional Health - Europe
Healthcare use in individuals with rheumatoid arthritis during the COVID-19 pandemic and beyond: A cohort study in three nations of the UK
COSTELLO, RE; Parker, M; Kennedy, J; Brophy, S; Mehrkar, A; Bacon, S; Goldacre, B; MacKenna, B; Evans, D; Tomlinson, L; Hollick, R; Humphreys, JH;
2025
openRxiv
Ursodeoxycholic acid and severe COVID-19 outcomes in a cohort study using the OpenSAFELY platform.
COSTELLO, RE; Waller, KM J; Smith, R; Mells, GF; WONG, AY S; SCHULTZE, A; MAHALINGASIVAM, V; HERRETT, E; Zheng, B; Lin, L-Y; MacKenna, B; Mehrkar, A; Bacon, SC J; Goldacre, B; TOMLINSON, LA; TAZARE, J; RENTSCH, CT; OpenSAFELY collaborative,; LH&W NCS (or CONVALESCENCE) Collaborative,;
2024
Communications medicine
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