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Ms Vanessa Yardley

PhD

Assistant Professor

Room
238B

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Tel.
0207 927 2462
Jump to: Affiliations Teaching Research Publications

1990: BSc (Hons) Biology (Parasitology), Kings College London

1991: MSc Medical Parasitology, LSHTM

2002: PhD University of London.  "Action of amphotericin B formulations on Leishmania spp. and Trypanosoma cruzi, in vitro and in vivo."

Affiliations
Department of Infection Biology
Faculty of Infectious and Tropical Diseases

Teaching

3122 'Parasitology & entomology" module co-organiser (past)

3133 Field Trip organiser and senior member of staff

Tutor and lecturer on various MSc programmes.

MSc Course committee member and Exam Board member - previously Chair

Supervision of PhD and MSc students for lab-based projects.

Taught Programme co-Director for ITD

Programme Content Director for DL Masters in Infectious Diseases

Research

Currently funded by Research Council, NGO, EU, GHIT on a variety of projects involving in vivo models of Leishmania infection, including development of improved dignostic tools, support for clinical trials, vaccine candidate evaluation and long standing drug evaluation programme.

Research Area
Clinical care
Clinical trials
Diagnostics
Drug discovery and development
Drug resistance
Parasites
Pharmacovigilance
Trypanosomes
Vaccines
Chemotherapy
Disease control
Pharmacokinetics
Protozoa
Discipline
Immunopathology
Cell biology
Molecular biology
Parasitology
Pharmacology
Disease and Health Conditions
Infectious disease
Malaria
African trypanosomiasis
Chagas Disease
Emerging Infectious Disease
Neglected Tropical Diseases (NTDs)
Skin disease
Tropical diseases
Zoonotic disease
Leishmaniasis
Human African trypanosomiasis
Region
World

Selected Publications
Artemisinin Cocrystals for Bioavailability Enhancement. Part 2: In Vivo Bioavailability and Physiologically Based Pharmacokinetic Modeling.
Kaur M; Yardley V; Wang K; Masania J; Arroo RRJ; Turner DB; Li M
2021
MOLECULAR PHARMACEUTICS
Artemisinin Cocrystals for Bioavailability Enhancement. Part 1: Formulation Design and Role of the Polymeric Excipient.
Kaur M; Yardley V; Wang K; Masania J; Botana A; Arroo RRJ; Li M
2021
MOLECULAR PHARMACEUTICS
DNDI-6148: A Novel Benzoxaborole Preclinical Candidate for the Treatment of Visceral Leishmaniasis
Mowbray CE; Braillard S; Glossop PA; Whitlock GA; Jacobs RT; Speake J; Pandi B; Nare B; Maes L; Yardley V
2021
DNDI-6148: A Novel Benzoxaborole Preclinical Candidate for the Treatment of Visceral Leishmaniasis.
Mowbray CE; Braillard S; Glossop PA; Whitlock GA; Jacobs RT; Speake J; Pandi B; Nare B; Maes L; Yardley V
2021
Journal of Medicinal Chemistry
Drug reformulation for a neglected disease. The NANOHAT project to develop a safer more effective sleeping sickness drug.
Sanderson L; da Silva M; Sekhar GN; Brown RC; Burrell-Saward H; Fidanboylu M; Liu B; Dailey LA; Dreiss CA; Lorenz C
2021
PLoS neglected tropical diseases
Novel Linker Variants of Antileishmanial/Antitubercular 7-Substituted 2-Nitroimidazooxazines Offer Enhanced Solubility.
Thompson AM; O'Connor PD; Yardley V; Maes L; Launay D; Braillard S; Chatelain E; Wan B; Franzblau SG; Ma Z
2021
ACS medicinal chemistry letters
Activity of Amphotericin B-Loaded Chitosan Nanoparticles against Experimental Cutaneous Leishmaniasis.
Riezk A; Van Bocxlaer K; Yardley V; Murdan S; Croft SL
2020
Molecules
Heteroaryl ether analogues of an antileishmanial 7-substituted 2-nitroimidazooxazine lead afford attenuated hERG risk: In vitro and in vivo appraisal.
Thompson AM; O'Connor PD; Marshall AJ; Yardley V; Maes L; Gupta S; Launay D; Braillard S; Chatelain E; Wan B
2020
European journal of medicinal chemistry
See more Publications
Vanessa Yardley

Contact

Room
238B

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Tel.
0207 927 2462