My research work involves the study of the virological and immunological correlates of HIV-1 superinfection, a phenomenon where HIV infected individuals become infected with other HIV strains following re-exposure to HIV. This work involves the use of next generation sequencing with phylogenetic analysis to determine HIV-1 superinfection and neutralization assays to determine the development of neutralizing antibodies prior to and after superinfection. My other research interests include studies on HIV-1 drug resistance and molecular epidemiology of HIV-1 in Uganda and the region. I am involved in H3ABionet, a network tasked to develop bioinformatics capacity in Africa. With colleagues at Makerere University, I am involved in the BRecA (Bioinformatics Research Capacity in Africa project) that is establishing sustainable programs at Makerere University to produce a critical mass of Bioinformaticians. Working with colleagues and Abbott diagnostics we are using metagenomics approaches to study pathogen discovery to address the emerging and re-emerging pathogens in Uganda and the region.