Professor Cally Roper
BSc PhD
Professor
in Malaria Genetics
LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom
My research applies evolutionary genetics to practical problems in malaria control. In particular I am interested in the emergence and spread of antimalarial drug resistance. My research involves mapping resistance mutations in Africa to inform policy on malaria prevention and treatment, and the development of new molecular tools for mapping the dispersal of resistance mutations.
Affiliations
Centres
Teaching
Module organiser for the distance learning Malaria module.
Research
Barcoding Malaria Parasites: A barcode of organellar genome polymorphisms identifies the geographic origin of Plasmodium falciparum strains. M.D. Preston, S. Campino, S.A. Assefa, D.F. Echeverry, H. Ocholla, A. Amambua-Ngwa, L. Stewart, D.J. Conway, S. Borrmann, P. Michon, I. Zongo, J-B Ouédraogo, A.A. Djimde, O.K. Doumbo, F. Nosten, A. Pain, T. Bousema, C.J. Drakeley, R.M. Fairhurst, C.J. Sutherland, C. Roper, T.G Clark. Nature Communications (2014) 5:4052.
Mapping the spread of drug resistance mutations in Africa http://www.drugresistancemaps.org/ Multiple Origins and Regional Dispersal of Resistant dhps in African Plasmodium falciparum Malaria. R. J. Pearce, H. Pota, M-S B. Evehe, E-H Bâ, G. Mombo-Ngoma, A. L. Malisa, R. Ord, W. Inojosa, A. Matondo, D.A. Diallo, W. Mbacham, I.V.van den Broek, T.D. Swarthout, A. Getachew, S. Dejene, M.P.Grobusch, F. Njie, S. Dunyo, M. Kweku, S. Owusu-Agyei, D. Chandramohan, M. Bonnet, J-P Guthmann, S. Clarke, K.I. Barnes, E. Streat, S.T. Katokele, P. Uusiku, C.O. Agboghoroma, O. Y. Elegba, B. Cissé, I. E. A-Elbasit, H.A. Giha, S.P. Kachur, C. Lynch, J.B. Rwakimari, P. Chanda, M. Hawela, B. Sharp, I. Naidoo, C. Roper. PLoS Medicine (2009) 6(4):e1000055
Measuring drug pressure in a field trial of intermittent preventive treatment of infants (IPTi). A community-randomised evaluation of the effect of IPTi on antimalarial drug resistance in southern Tanzania. R. J. Pearce , R. Ord, H. Kaur, C. Lupala , J. Schellenberg, K. Shirma, F. Manzi, M. Tanner, P. Alonso, H. Mshinda, C. Roper, D. Schellenberg. The Journal of Infectious Diseases (2013) 207, 849-859.