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Dr Natacha Protopopoff

PhD

Assistant Professor
of entomology

National Institute of Medical Research
Mwanza
Tanzania

Tel.
+255752474969

I am particularly interested in operational research that will help countries to take sound decisions on vector control strategy that is based on scientific evidence. I have spent the last 20 years implementing large scale entomological and parasitological trials evaluating malaria vector control interventions. I joined LSHTM in 2011 and I am currently based in Mwanza, (Tanzania). For the LSHTM, I have been managing large randomized control trial investigating the impact of new vector control tools on vector outcomes and malaria transmission. My ongoing research is to assess the efficacy of two new dual insecticide treated nets on malaria prevalence in Tanzania and Benin in area where the main vectors are resistant to pyrethroid insecticides. 

My background is on biochemistry and undertook a master in environmental sciences and water management. This led me to work with Médecins Sans Frontière as a water and sanitation officer and manage my first malaria vector control project. I spent several years in Burundi managing Indoor Residual Spray campaigns and insecticide treated nets distributions and evaluating the impact of these interventions on vector abundance and malaria prevalence. I completed a PhD in 2008 with the Institute of Tropical Medicine in Antwerp Belgium which investigated the impact of targeted vector control on malaria transmission in the African highlands.

In 2009 I joined the Malaria Consortium as vector control specialist supporting the Uganda, South Sudan, Senegal and Ghana National Malaria Control Programmes to establish their malaria vector control strategy and net distribution systems. I was involved in research to evaluate the durability of LLIN in phase III trials in Uganda. With the vector control division of the Ugandan NMCP I established insecticide resistance susceptibility monitoring in sentinel sites throughout Uganda.

Affiliations

Faculty of Infectious and Tropical Diseases
Department of Disease Control

Centres

Malaria Centre
Health in Humanitarian Crises Centre

Teaching

I teach vector biology and control, give lectures and practical to the East African Diploma of Tropical Medicine & Hygiene held each year in Tanzania. Since 2013, I am a tutor on the malaria module of the Infectious Diseases distance learning programme. I am supervising LSHTM, Kilimanjaro Christian Medical University College (Tanzania) and University of Antwerp (Belgium) MSc dissertation project students in Tanzania. I am teaching in the course led by MSF on vector control in emergency situation.

 

Research

 1. Community randomized control trials evaluating of new vector control tool and/or strategies.

  • PI of two RCT to assess the efficacy of next generation of insecticide treated nets combining two insecticides, in Tanzania(MRC/DfID/Wellcome Global Health Trials) and in Benin (UNITAID)
 
  • Co Pi and manager of a project funded by MRC/DfID/Wellcome Global Health Trials to evaluate single and combination interventions aimed at controlling malaria transmitted by pyrethroid resistant mosquitoes: a novel long lasting net incorporating a synergist and a long lasting IRS formulation (2014-2018)
  • Manager of a 3 years community randomized control trial evaluating the impact of combining Insecticide Treated Net and Indoor Residual Spraying on Malaria funded by PMI/USAID in Northern Tanzania (2010-2013).
  • Scientific support to a community randomized control trial examining the efficacy of insecticide-treated durable wall liners (ITWL) as a method for malaria control in endemic rural Tanzania funded by PMI/USAID

2. Development of novel malaria vector control tools with IVCC

  • Manager of laboratory (phase I) and small scale studies (phase II) evaluating new long lasting insecticide net or indoor residual spray formulations through the Innovative Vector Control Consortium (IVCC), a Gates funded project

3. Co-PI for a project investigating malaria transmission in Lower Moshi and training medical students in research as part of the Medical Education Partnership Initiative mentored Research and Training (Duke University School of Medicine and KCMC).

 

Research Area
Clinical trials
Complex interventions
Disease control
Implementation research
Randomised controlled trials
Vector control
Discipline
Epidemiology
Operational research
Parasitology
Vector biology
Entomology
Disease and Health Conditions
Malaria
Vector borne disease
Country
Burundi
Ghana
Senegal
South Sudan
Tanzania
Uganda
Region
Sub-Saharan Africa (all income levels)

Selected Publications

Evaluation of next generation of insecticide treated nets: The Tanzanian experiences
Mosha JF; Lukole E; Mosha FW; Manjurano A; Martin J; Kulkarni M; Mwalimu CD; Rowland M; Protopopoff N
2019
Transactions of the Royal Society of Tropical Medicine and Hygiene
Dawn of the PBO-Pyrethroid Long Lasting Net – Light at Last
Rowland M; Protopopoff N
2019
Outlooks on Pest Management
Studies on the resting behaviour and host choice of Anopheles gambiae and An. arabiensis from Muleba, Tanzania.
Charlwood JD; Kessy E; Yohannes K; Protopopoff N; Rowland M; LeClair C
2018
Medical and veterinary entomology
Systematic review of indoor residual spray efficacy and effectiveness against Plasmodium falciparum in Africa.
Sherrard-Smith E; Griffin JT; Winskill P; Corbel V; Pennetier C; Djénontin A; Moore S; Richardson JH; Müller P; Edi C
2018
Nature Communications
The Furvela tent-trap Mk 1.1 for the collection of outdoor biting mosquitoes.
Charlwood JD; Rowland M; Protopopoff N; Le Clair C
2017
PeerJ
Insecticide resistance in Anopheles gambiae and An. funestus in two rural sites in Tanzania
Weston SJ; Protopopoff N; Batengana B; Malima R; Sudi W; Mosha F; Rowland M
2017
American Journal of Tropical Medicine and Hygiene
See more Publications