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Dr Nathaniel Lee

Res - LSHTM-Nagasaki University Joint PhD Programme for Global Health - Epidemiology & Population Health

United Kingdom

I am a PhD student on the Nagasaki University – London School of Hygiene and Tropical Medicine Joint PhD for Global Health. I am an ID physician by background, and have a longstanding academic interest in Leptospirosis, Tuberculosis, and Neglected Tropical Diseases

The evidence for the management of leptospirosis, particularly in severe disease, is clouded by methodological inconsistency and a lack of established outcome measures. The primary aim of my PhD is to systematically address gaps in research evidence for the management of Leptospirosis in order to identify a therapeutic intervention to test in a rigorously designed multi-site international clinical trial.

I am keen to form inter-institutional collaborative projects with centres where Leptospirosis is managed, with the goal of developing an academic network that can be used to build towards an international clinical trial of a single or multiple interventions for Leptospirosis.

Affiliations

Department of Infectious Disease Epidemiology and International Health
Faculty of Epidemiology and Population Health

Teaching

I am contributing regularly to the Nagasaki Diploma in Tropical Medicine and Hygiene, and have a coordination role in the Nagasaki University's Philippines Tropical Medicine Course.

Research

Research Area
Clinical medicine
Clinical trials
Outbreaks
Health outcomes
Disease and Health Conditions
Leptospirosis
Tuberculosis
Neglected Tropical Diseases (NTDs)
Emerging infectious diseases
Country
Malaysia
Philippines
Vietnam
Japan
Region
East Asia & Pacific (all income levels)
Latin America & Caribbean (all income levels)

Selected Publications

Leptospirosis-clinical review and updates on therapeutics
LEE, N; Tanaka, T; Koizumi, N; Coughlan, C; Sayo, AR; Ariyoshi, K; EDWARDS, T; SMITH, C; BAILEY, R;
2026
The Lancet infectious diseases
Re-emergence of Leptospirosis in Flood-Prone Areas of Metro Manila: The Need for Climate-Resilient Health Interventions
Han, SM; SMITH, C; LEE, N; Sayo, AR;
2025
Overview of the San Lazaro Hospital-Nagasaki University Collaborative Research and Training Activities
SMITH, C; Sayo, AR; Suzuki, S; Villaneuva, A; Yoshino, J; Balein, R; Girasol, M; LEE, N; Han, SM;
2025
Japanese Society of Tropical Medicine Annual Conference
Philippines-Japan collaborative study with OMICS approach to unveil molecular characteristics of leptospirosis (LEPTO-OMICS study)
Villanueva, A; LEE, N; Haron, I; Amer, A; Uyam, D; Girasol, M; Suzuki, S; Salazar, MJ; SMITH, C; Furuse, Y;
2025
Japanese Society of Tropical Medicine Annual Conference
Corticosteroids for treatment of leptospirosis.
LEE, N; Han, SM; Mukadi, P; EDWARDS, T; Maung, HT; SMITH, C; Win, TZ;
2025
Cochrane Database of Systematic Reviews
Tropical Medicine Education & Training in Japan
SMITH, C; Moriya, A; Win, TZ; Matsui, K; Suzuki, SJ; LEE, N; Sayo, AR; Girasol, M; Ortal, A; Balein, MR; Nakandakari, M; Kita, K; Ariyoshi, K;
2024
Joint Congress on Global Health 2024
Antibiotics for treatment of leptospirosis.
Win, TZ; HAN, SM; EDWARDS, T; Maung, HT; Brett-Major, DM; SMITH, C; LEE, N;
2024
The Cochrane database of systematic reviews
Antibiotic prophylaxis for leptospirosis.
Win, TZ; Perinpanathan, T; Mukadi, P; SMITH, C; EDWARDS, T; HAN, SM; Maung, HT; Brett-Major, DM; LEE, N;
2024
The Cochrane database of systematic reviews
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