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Quentin Leclerc

BSc MSc

Research Degree Student
in Mathematical Modelling of Infectious Diseases

Room
LG22

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Jump to: Affiliations Research Publications

I am a final year PhD student at LSHTM in mathematical modelling of methicilin-resistant Staphylococcus aureus (MRSA). As part of this, I also conduct lab work at St George's University of London. I started my project in 2018 and am funded by the MRC London Intercollegiate Doctoral Training Partnership programme.

Previously, I completed an MSc in Epidemiology (2017-18), and a BSc in Microbiology (2014-17), both at Imperial College London.

For more information on my work and me, please refer to my personal website.

Affiliations
Faculty of Epidemiology and Population Health
Department of Infectious Disease Epidemiology

Centres

Centre for the Mathematical Modelling of Infectious Diseases (CMMID)
Antimicrobial Resistance Centre (AMR)

Research

My research focuses on understanding phage-bacteria interactions, notably the dynamics of transduction (horizontal gene transfer mediated by bacteriophage, viruses of bacteria). I am particularly interested in how transduction can lead to the spread of antimicrobial resistance genes in MRSA. For this, I generate in vitro data in the lab, and develop mathematical models to reveal the underlying dynamics of phage and bacteria.

Research Area
Bacteria
Drug resistance
Modelling
Discipline
Epidemiology
Microbiology
Mathematical modelling
Statistics
Disease and Health Conditions
Infectious disease
Hospital acquired infection

Selected Publications
Growth-Dependent Predation and Generalized Transduction of Antimicrobial Resistance by Bacteriophage.
Leclerc QJ; Wildfire J; Gupta A; Lindsay JA; Knight GM
2022
mSystems
Antimicrobial resistance and COVID-19: Intersections and implications.
Knight GM; Glover RE; McQuaid CF; Olaru ID; Gallandat K; Leclerc QJ; Fuller NM; Willcocks SJ; Hasan R; van Kleef E
2021
eLife
Importance of patient bed pathways and length of stay differences in predicting COVID-19 hospital bed occupancy in England.
Leclerc QJ; Fuller NM; Keogh RH; Diaz-Ordaz K; Sekula R; Semple MG; ISARIC4C Investigators; CMMID COVID-19 Working Group; Atkins KE; Procter SR
2021
BMC health services research
What settings have been linked to SARS-CoV-2 transmission clusters?
Leclerc QJ; Fuller NM; Knight LE; Funk S; Knight GM
2020
Wellcome Open Research
Feasibility of informing syndrome-level empiric antibiotic recommendations using publicly available antibiotic resistance datasets
Leclerc QJ; Naylor NR; Aiken AM; Coll F; Knight GM
2020
Wellcome Open Research
Analysis of temporal trends in potential COVID-19 cases reported through NHS Pathways England.
Leclerc QJ; Nightingale ES; Abbott S; CMMID COVID-19 Working Group; Jombart T
2020
Scientific reports
Comparing the Analysis and Results of a Modified Social Accounting Matrix Framework with Conventional Methods of Reporting Indirect Non-Medical Costs.
Standaert B; Sauboin C; Leclerc QJ; Connolly MP
2020
PHARMACOECONOMICS
Mathematical modelling to study the horizontal transfer of antimicrobial resistance genes in bacteria: current state of the field and recommendations
Leclerc QJ; Lindsay JA; Knight GM
2019
Journal of The Royal Society Interface
See more Publications
Quentin Leclerc

Contact

Room
LG22

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom