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Dr Ozan Gundogdu

BSc MSc PhD

Principal Scientific Officer
- Bioinformatician/Microbiologist

Room
380

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Tel.
02079588383

Ozan joined the LSHTM in 2004 and is a dual qualified bioinformatician and microbiologist. Before joining the School he completed a BSc Honours in Molecular Biology followed by an MSc Computer Science (Commendation), both at the University of Hertfordshire. His undergraduate also contained an industrial placement year which was completed at RAFT - Institute of Plastic Surgery, where he was research assistant in the Molecular Biology group. Ozan completed his PhD in 2011 studying the microbial pathogenesis of Campylobacter jejuni.

Affiliations

Faculty of Infectious and Tropical Diseases
Department of Pathogen Molecular Biology

Teaching

Ozan has successfully completed the Postgraduate Certificate in Learning and Teaching (Full Certificate) at the LSHTM and has become a Fellow of the Higher Education Academy (FHEA). He has a wide range of teaching activities which include:-

  • Lecturing on the "Molecular Biology" (3333) and "Molecular Biology Research Progress & Applications" (3160) modules as part of the Molecular Biology of Infectious Diseases (MBID) and Medical Microbiology (MM) MSc courses
  • Laboratory and faculty demonstrations as part of the above courses
  • Tutoring and co-supervision of PhD / MSc students with projects involving a laboratory or bioinformatics theme
  • PhD / MSc exam marking and invigilation
  • Advisory panel for PhD students
  • Teaching internal and external researchers about a number of faculty equipment and also data analysis techniques
  • Setting up modules as part of a distance learning course
  • Member of Senate Council

Along with teaching, Ozan is the Head of Sequencing at the LSHTM which includes an Illumina MiSeq and an ABI3730 sequencer. 

Research

Current research interests relating to the study of bacterial pathogenesis include:-

  • Mechanisms of Campylobacter jejuni response to environmental and host stress
  • Prevalence and characterising C. jejuni Type Six Secretion Systems (T6SS)
  • Survival and persistence mechanisms of C. jejuni in relation to host cells
  • Microbiota studies focusing on C. jejuni and AMR
  • Bacterial omics linked to the above themes e.g. genomics, transcriptomics and metagenomics

Ozan has completed the full re-annotation of the C. jejuni NCTC11168 genome (in collaboration with the Sanger Institute) and has created and runs the Campylobacter Resource Facility (CRF) website.

In addition to the above, Ozan has linked to a number of other internal and external projects which include a next-generation sequencing/bioinformatics theme. He is actively involved in enhancing the school's sequencing / bioinformatics software tools. Ozan is responsible for running and maintaining the Genome Resource Facility within the Pathogen Molecular Biology department and has created and runs the Genome Resource Facility (GRF) website.

Ozan is a full member of the Society for General Microbiology (SGM) and an Associate Faculty Member of Faculty of 1000 (post-publication peer review).

Research Area
Bacteria
Disease control
Discipline
Genomics
Bacteriology
Microbiology
Molecular biology
Bioinformatics
Disease and Health Conditions
Diarrhoeal diseases
Infectious disease
Zoonotic disease
Region
World

Selected Publications

Assessment of the influence of intrinsic environmental and geographical factors on the bacterial ecology of pit latrines.
Torondel, B.; Ensink, J.H.; Gundogdu, O.; Ijaz, U.Z.; Parkhill, J.; Abdelahi, F.; Nguyen, V.A.; Sudgen, S.; Gibson, W.; Walker, A.W.; Quince, C.;
Microb Biotechnol
The Campylobacter jejuni Oxidative Stress Regulator RrpB Is Associated with a Genomic Hypervariable Region and Altered Oxidative Stress Resistance.
Gundogdu, O. ; da Silva, D.T. ; Mohammad, B. ; Elmi, A. ; Wren, B.W. ; van Vliet, A.H. ; Dorrell, N. ;
Front Microbiol
Prevalence of Type VI Secretion System in Spanish Campylobacter jejuni Isolates.
Ugarte-Ruiz, M.; Stabler, R.A.; Domínguez, L.; Porrero, M.C.; Wren, B.W.; Dorrell, N.; Gundogdu, O.;
Zoonoses Public Health
The Campylobacter jejuni MarR-like transcriptional regulators RrpA and RrpB both influence bacterial responses to oxidative and aerobic stresses.
Gundogdu, O. ; da Silva, D.T. ; Mohammad, B. ; Elmi, A. ; Mills, D.C. ; Wren, B.W. ; Dorrell, N. ;
Front Microbiol
Understanding and Managing Zoonotic Risk in the New Livestock Industries.
Liverani, M.; Waage, J.; Barnett, T.; Pfeiffer, D.U.; Rushton, J.; Rudge, J.W.; Loevinsohn, M.E.; Scoones, I.; Smith, R.D.; Cooper, B.S.; White, L.J.; Goh, S.; Horby, P.; Wren, B.; Gundogdu, O.; Woods, A.; Coker, R.J.;
Environ Health Perspect
Re-annotation and re-analysis of the Campylobacter jejuni NCTC11168 genome sequence.
Gundogdu, O.; Bentley, S.D.; Holden, M.T.; Parkhill, J.; Dorrell, N.; Wren, B.W.;
BMC Genomics
Comparative phylogenomics of the food-borne pathogen Campylobacter jejuni reveals genetic markers predictive of infection source.
Champion, O.L.; Gaunt, M.W.; Gundogdu, O.; Elmi, A.; Witney, A.A.; Hinds, J.; Dorrell, N.; Wren, B.W.;
Proc Natl Acad Sci U S A
See all Dr Ozan Gundogdu's Publications