Dr Ozan Gundogdu
BSc MSc PhD
Principal Scientific Officer
Ozan Gundogdu joined the LSHTM in 2004 and is a dual qualified bioinformatician and microbiologist. Before joining the School he completed a BSc Honours in Molecular Biology followed by an MSc Computer Science (Commendation), both at the University of Hertfordshire. His undergraduate also contained an industrial placement year which was completed at RAFT - Institute of Plastic Surgery, where he was research assistant in the Molecular Biology group. Ozan completed his PhD in 2011 studying the microbial pathogenesis of Campylobacter jejuni and is continuing to study the pathogenicity of Campylobacter and other related bacteria using classical molecular microbiology techniques along with cutting-edge omics based approaches e.g. genomics, transcriptomics and metagenomics.
Ozan has successfully completed the Postgraduate Certificate in Learning and Teaching (Full Certificate) at the LSHTM and has become a Fellow of the Higher Education Academy (FHEA). He has a wide range of teaching activities which include:-
- Lecturing on the "Molecular Biology Research Progress & Applications" (3160) module (since 2010)
- Lecturing on the "Molecular Biology" (3333) module (since 2011)
- Both above lectures are part of the Molecular Biology of Infectious Diseases (MBID) and Medical Microbiology (MM) MSc courses at the LSHTM
- Laboratory and faculty demonstrations as part of MBID and MM courses (since 2006)
- MSc exam marking and invigilation (since 2006)
- Tutoring MSc students throughout the academic year (11 students since 2004)
- Advisory panel for PhD students (two students since 2011)
- PhD upgrade (two students 2014, 2016) and viva (one student 2017) examiner
- Teaching internal and external researchers about a number of faculty equipment and also data analysis techniques (since 2004)
- Setting up modules as part of a distance learning course (IDM602)
- Member of Senate Council
Ozan currently supervises two PhD students and also supervises MSc research projects at the LSHTM (nine students since 2006).
Along with teaching, Ozan is the Head of Sequencing at the LSHTM which includes an Illumina MiSeq and an ABI3730 sequencer. He is actively involved in enhancing the School's sequencing / bioinformatics set-up and is responsible for running and maintaining the Genome Resource Facility within the Pathogen Molecular Biology department and has created and runs the Genome Resource Facility (GRF) website.
Ozan's research interests and vision are to study the pathogenesis of Campylobacter, the leading human foodborne pathogen, and related microorganisms with the aim of increasing our understanding of virulence mechanisms, survival properties and physiology of such pathogens, thus allowing us to implement intervention and control strategies. Over the last 14 years, he has utilized classical molecular microbiology techniques, and more recently linked his bioinformatics skills to cutting-edge omics based approaches such as genomics, transcriptomics and metagenomics in his research.
Current research interests include investigating the pathogenesis of Campylobacter and other related bacteria with the following themes:-
- Mechanisms of Campylobacter jejuni response to environmental and host stress
- Prevalence and characterising C. jejuni Type Six Secretion Systems (T6SS)
- Survival and persistence mechanisms of C. jejuni in relation to host cells
- Microbiota studies focusing on C. jejuni and AMR
- Bacterial omics linked to the above themes e.g. genomics, transcriptomics and metagenomics
In relation to Campylobacter, he has completed the full re-annotation of the C. jejuni NCTC11168 genome (in collaboration with the Sanger Institute) and has created and runs the Campylobacter Resource Facility (CRF) website. He has also linked to a number of additional internal and external projects which include a next-generation sequencing/bioinformatics theme with the aim of enhancing research output and funding opportunities.
Ozan is active in presenting at national and international conferences relating to Campylobacter research and has presented at a number of meetings (12 since 2007), most recently an oral presentation at the CHRO 2017, Nantes, France. He is is a full member of the Microbiology Society (Previously known as the Society of General Microbiology) and an Associate Faculty Member of Faculty of 1000 (post-publication peer review). He is also active in refereeing papers from different journals (11 papers since 2013) and grant applications from different funding bodies (four totalling £14 million since 2013).