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Prof Brendan Wren

Professor of Microbial Pathogenesis

United Kingdom

Tel.
02079272288
Jump to: Affiliations Publications

Affiliations
Department of Infection Biology
Faculty of Infectious and Tropical Diseases

Centres

Centre for Epidemic Preparedness and Response
Vaccine Centre
Antimicrobial Resistance Centre

Selected Publications
A combinatorial DNA assembly approach to biosynthesis of N-linked glycans in E. coli.
PASSMORE, IJ; Faulds-Pain, A; ABOUELHADID, S; HARRISON, MA; Hall, CL; Hitchen, P; Dell, A; Heap, JT; WREN, BW;
2023
Glycobiology
Engineering a suite of E. coli strains for enhanced expression of bacterial polysaccharides and glycoconjugate vaccines.
KAY, EJ; MAURI, M; WILLCOCKS, SJ; SCOTT, TA; CUCCUI, J; WREN, BW;
2022
MICROBIAL CELL FACTORIES
Development of an automated platform for the optimal production of glycoconjugate vaccines expressed in Escherichia coli.
Samaras, JJ; MAURI, M; KAY, EJ; WREN, BW; Micheletti, M;
2021
Microbial cell factories
Characterization of Posttranslationally Modified Multidrug Efflux Pumps Reveals an Unexpected Link between Glycosylation and Antimicrobial Resistance.
ABOUELHADID, S; RAYNES, J; Bui, T; CUCCUI, J; WREN, BW;
2020
mBio
Adaptation of host transmission cycle during Clostridium difficile speciation.
Kumar, N; Browne, HP; Viciani, E; Forster, SC; Clare, S; Harcourt, K; Stares, MD; Dougan, G; Fairley, DJ; Roberts, P; Pirmohamed, M; Clokie, MR J; Jensen, MB F; Hargreaves, KR; Ip, M; Wieler, LH; Seyboldt, C; Norén, T; Riley, TV; Kuijper, EJ; WREN, BW; Lawley, TD;
2019
NATURE GENETICS
Recent advances in the production of recombinant glycoconjugate vaccines.
KAY, E; CUCCUI, J; WREN, BW;
2019
NPJ vaccines
Quantitative Analyses Reveal Novel Roles for N-Glycosylation in a Major Enteric Bacterial Pathogen.
ABOUELHADID, S; North, SJ; Hitchen, P; Vohra, P; Chintoan-Uta, C; Stevens, M; Dell, A; CUCCUI, J; WREN, BW;
2019
mBio
A recombinant conjugated pneumococcal vaccine that protects against murine infections with a similar efficacy to Prevnar-13.
Reglinski, M; Ercoli, G; Plumptre, C; KAY, E; Petersen, FC; Paton, JC; WREN, BW; Brown, JS;
2018
NPJ vaccines
Para-cresol production by Clostridium difficile affects microbial diversity and membrane integrity of Gram-negative bacteria.
PASSMORE, IJ; Letertre, MP M; Preston, MD; Bianconi, I; HARRISON, MA; NASHER, F; KAUR, H; Hong, HA; Baines, SD; Cutting, SM; Swann, JR; WREN, BW; DAWSON, LF;
2018
PLoS pathogens
The N-linking glycosylation system from Actinobacillus pleuropneumoniae is required for adhesion and has potential use in glycoengineering.
CUCCUI, J; TERRA, VS; Bossé, JT; Naegeli, A; ABOUELHADID, S; Li, Y; Lin, C-W; Vohra, P; Tucker, AW; Rycroft, AN; Maskell, DJ; Aebi, M; Langford, PR; WREN, BW; BRaDP1T Consortium,;
2017
Open biology
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Contact

United Kingdom

Tel.
02079272288