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Prof Charlotte Warren-Gash

Clin Prof of Epi & Health Data Science

United Kingdom

I am a Professor of Epidemiology and honorary consultant in Public Health Medicine. My research uses large health datasets to investigate causes of disease in older age to inform prevention strategies. I am currently supported by a Wellcome Career Development Award focussed on understanding relationships between infections and brain health: https://wellcome.org/grant-funding/people-and-projects/grants-awarded/i… as well as through research grants from Open Philanthropy.

I originally qualified in medicine from Edinburgh University and trained in internal medicine in Edinburgh and London hospitals before specialising in public health. I completed an MSc in epidemiology at LSHTM in 2007. My MRC-funded PhD, awarded by UCL in 2013, investigated the role of influenza as a trigger for acute cardiovascular events. After post-doctoral experience as an NIHR clinical lecturer at the UCL Institute of Health Informatics, I joined LSHTM on a Wellcome Intermediate Clinical Fellowship in 2016.

Affiliations

Department of Non-communicable Disease Epidemiology
Faculty of Epidemiology and Population Health

Teaching

I am joint Departmental Research Degree Co-ordinator for the NCDE department. I am Deputy Chair of the exam board for the professional certificate in pharmacoepidemiology & pharmacovigilance and course organiser for the short course 'Systematic Reviews and Meta Analyses of Health Research'. I also teach on various MSc modules including Extended Epidemiology, Study Design and Advanced Research Methods and supervise MSc summer projects and PhD students.

Research

My research seeks to understand causes of disease in older age with a focus on how infections interact with other health conditions. I lead a programme of research funded by a Wellcome Career Development Award which aims to investigate relationships between infections and key components of brain health (mental health, cognitive health and sensorimotor function) in older age. This uses large, longitudinal datasets from across populations along with robust causal inference methods. Through generating new insights into the infection-brain health relationship across and within different populations, my research aims to inform the design of interventions to improve brain health worldwide.

I am also leading a large collaborative project funded by Open Philanthropy to enhance the UK Biobank dataset with additional infectious disease data to enable research into infections and non-communicable disease links.

My other research interests include social and environmental influences on health, health inequalities, vaccine epidemiology and phenotyping methods.

Research Area
Ageing
Electronic health records
Older people's health
Public health
Systematic reviews
Epidemiology
Medicine
Virology
Health inequalities
Disease and Health Conditions
Herpesviruses
Influenza
Pandemic diseases
Stroke
Infectious diseases
Neurological diseases
Cardiovascular diseases

Selected Publications

Risk of herpes zoster after exposure to varicella to explore the exogenous boosting hypothesis: self controlled case series study using UK electronic healthcare data.
FORBES, H; DOUGLAS, I; Finn, A; Breuer, J; BHASKARAN, K; SMEETH, L; Packer, S; LANGAN, SM; MANSFIELD, KE; Marlow, R; Whitaker, H; WARREN-GASH, C;
2020
BMJ-BRITISH MEDICAL JOURNAL
Human herpesvirus infections and dementia or mild cognitive impairment: a systematic review and meta-analysis.
WARREN-GASH, C; FORBES, HJ; WILLIAMSON, E; Breuer, J; Hayward, AC; Mavrodaris, A; Ridha, BH; Rossor, MN; Thomas, SL; SMEETH, L;
2019
Scientific reports
Incident dementia risk among patients with type 2 diabetes receiving metformin versus alternative oral glucose-lowering therapy: an observational cohort study using UK primary healthcare records.
Doran, W; TUNNICLIFFE, L; Muzambi, R; RENTSCH, CT; BHASKARAN, K; SMEETH, L; Brayne, C; Williams, DM; Chaturvedi, N; Eastwood, SV; Dunachie, SJ; Mathur, R; WARREN-GASH, C;
2024
BMJ open diabetes research & care
Common infections and neuroimaging markers of dementia in three UK cohort studies.
Green, RE; Sudre, CH; WARREN-GASH, C; Butt, J; Waterboer, T; Hughes, AD; Schott, JM; Richards, M; Chaturvedi, N; Williams, DM;
2024
Alzheimer's & dementia : the journal of the Alzheimer's Association
Herpes Zoster and Risk of Incident Parkinson's Disease in US Veterans: A Matched Cohort Study.
TUNNICLIFFE, L; Weil, RS; Breuer, J; Rodriguez-Barradas, MC; SMEETH, L; RENTSCH, CT; WARREN-GASH, C;
2024
Movement disorders : official journal of the Movement Disorder Society
Sleeplessness and incident diabetes above the Arctic circle: a secondary analysis of cohort data from the Tromsø Study
Uthaikhaifar, NC; Iakunchykova, O; Cook, S; WARREN-GASH, C;
2024
BMJ Public Health
Code lists for "Association between mortality and warfarin comparing with direct oral anticoagulants: a population-based cohort study"
WANG, Z; WONG, A; MATTHEWMAN, J; WARREN-GASH, C; HERRETT, E;
2023
London School of Hygiene & Tropical Medicine
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