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Dr Don Van Schalkwyk

Assistant Professor

United Kingdom

Affiliations

Department of Infection Biology
Faculty of Infectious and Tropical Diseases

Research

Research Area
Parasitology
Cell biology
Drug discovery and development
Drug resistance
Disease and Health Conditions
Malaria
Country
United Kingdom

Selected Publications

Ex vivo susceptibility to new antimalarial agents differs among human-infecting Plasmodium species.
VAN SCHALKWYK, DA; MOON, RW; Duffey, M; Leroy, D; SUTHERLAND, CJ;
2021
International journal for parasitology. Drugs and drug resistance
Clinical management of Plasmodium knowlesi malaria.
Barber, BE; Grigg, MJ; Cooper, DJ; VAN SCHALKWYK, DA; William, T; Rajahram, GS; Anstey, NM;
2021
Advances in parasitology
The Plasmodium falciparum Artemisinin Susceptibility-Associated AP-2 Adaptin μ Subunit is Clathrin Independent and Essential for Schizont Maturation.
Henrici, RC; Edwards, RL; Zoltner, M; VAN SCHALKWYK, DA; Hart, MN; MOHRING, F; MOON, RW; Nofal, SD; PATEL, A; FLUECK, C; BAKER, DA; Odom John, AR; Field, MC; Sutherland, CJ;
2020
mBio
Novel Endochin-Like Quinolones Exhibit Potent In Vitro Activity against Plasmodium knowlesi but Do Not Synergize with Proguanil.
VAN SCHALKWYK, DA; Riscoe, MK; Pou, S; Winter, RW; Nilsen, A; Duffey, M; MOON, RW; Sutherland, CJ;
2020
Antimicrobial Agents and Chemotherapy
Modification of pfap2μ and pfubp1 Markedly Reduces Ring-Stage Susceptibility of Plasmodium falciparum to Artemisinin In Vitro.
HENRICI, RC; VAN SCHALKWYK, DA; SUTHERLAND, CJ;
2019
Antimicrobial Agents and Chemotherapy
Plasmodium knowlesi exhibits distinct in vitro drug susceptibility profiles from those of Plasmodium falciparum.
VAN SCHALKWYK, DA; Blasco, B; Davina Nuñez, R; Liew, JW K; Amir, A; Lau, YL; Leroy, D; MOON, RW; SUTHERLAND, CJ;
2019
International journal for parasitology. Drugs and drug resistance
Comparison of the susceptibility of Plasmodium knowlesi and Plasmodium falciparum to antimalarial agents.
VAN SCHALKWYK, DA; MOON, RW; Blasco, B; SUTHERLAND, CJ;
2017
The Journal of antimicrobial chemotherapy
Verapamil-Sensitive Transport of Quinacrine and Methylene Blue via the Plasmodium falciparum Chloroquine Resistance Transporter Reduces the Parasite's Susceptibility to these Tricyclic Drugs.
VAN SCHALKWYK, DA; Nash, MN; Shafik, SH; Summers, RL; Lehane, AM; Smith, PJ; Martin, RE;
2015
The Journal of infectious diseases
The Mu subunit of Plasmodium falciparum clathrin-associated adaptor protein 2 modulates in vitro parasite response to artemisinin and quinine.
HENRIQUES, G; VAN SCHALKWYK, DA; Burrow, R; WARHURST, DC; Thompson, E; BAKER, DA; Fidock, DA; Hallett, R; FLUECK, C; SUTHERLAND, CJ;
2015
Antimicrobial agents and chemotherapy
Culture-adapted Plasmodium falciparum isolates from UK travellers: in vitro drug sensitivity, clonality and drug resistance markers.
VAN SCHALKWYK, DA; Burrow, R; HENRIQUES, G; Gadalla, NB; BESHIR, KB; Hasford, C; Wright, SG; Ding, XC; CHIODINI, PL; SUTHERLAND, CJ;
2013
Malaria journal
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