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Professor Liam Smeeth

MBChB FRCGP FFPH FRCP MSc PhD FMedSci

Professor
of Clinical Epidemiology

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Tel.
020 7927 2296

Fax.
020 7580 6897

I trained in medicine and continue to do clinical work as a general practitioner in north London. I joined LSHTM in 1999 and have held fellowships from NIHR, MRC and Wellcome. As well as academic and clinical work I am involved in a range of activities for the National Institute of Health and Care Excellence (NICE), the Medicines and Healthcare Products Regulatory Agency (MHRA) and the UK National Health Service more widely. I am a Trustee of the British Heart Foundation, a member of the steering group for UK Biobank, and an elected Fellow of the Academy of Medical Sciences.

Affiliations

Faculty of Epidemiology and Population Health
Department of Non-communicable Disease Epidemiology

Centres

Centre for Global Chronic Conditions

Teaching

I am involved in wide range of teaching activities and was previously course director of the MSc epidemiology and then chair of the exam board.

Research

My major interests are in disease aetiology and drug treatments. Two broad themes are the optimal use of computerised health data and non-communicable diseases in low and middle income countries, with a particular focus on cardiovascular disease and diabetes. Examples of recently completed projects include the impact of media coverage on use of statins, and the largest single study investigating the relationship between body mass index and cancer.  Current projects include StatinWise, a series of n of 1 trials to assess whether statins cause muscle symptoms; helping establish an electronic records based cohort of 100 million people in Brazil; and a multi-centre study establishing how best to measure kidney function in sub-Saharan Africa.

Electronic Health Records Research Group

Research Area
Clinical care
Clinical databases
Clinical trials
Health services research
Pharmacovigilance
Primary care
Systematic reviews
Vaccines
Electronic health records
Randomised controlled trials
Discipline
Genetic epidemiology
Pharmacoepidemiology
Epidemiology
Medicine
Disease and Health Conditions
Cancer
Cardiovascular disease
Chronic disease
Herpesviruses
Asthma
Diabetes
Kidney disease
Non-communicable diseases
Obesity
Respiratory disease
Stroke
Country
United Kingdom
Ghana
India
Peru
Uganda
Region
European Union
Latin America & Caribbean (all income levels)
Sub-Saharan Africa (all income levels)
World

Selected Publications

Methods to generate and validate a Pregnancy Register in the UK Clinical Practice Research Datalink primary care database
Minassian C; Williams R; Meeraus WH; Smeeth L; Campbell OMR; Thomas SL
2019
Pharmacoepidemiology and Drug Safety
Community-Level Knowledge and Perceptions of Stroke in Rural Malawi.
Mvula H; Chisambo C; Nyirenda V; Geis S; Glynn JR; Crampin AC; Nyirenda M; Smeeth L; Walker R; Price AJ
2019
Stroke
Associations between measures of sarcopenic obesity and risk of cardiovascular disease and mortality: a cohort study and Mendelian randomization analysis using the UK Biobank.
Farmer RE; Mathur R; Schmidt AF; Bhaskaran K; Fatemifar G; Eastwood SV; Finan C; Denaxas S; Smeeth L; Chaturvedi N
2019
Journal of the American Heart Association
Association of BMI with overall and cause-specific mortality: a population-based cohort study of 3·6 million adults in the UK.
Bhaskaran K; Dos-Santos-Silva I; Leon DA; Douglas IJ; Smeeth L
2018
The lancet. Diabetes & endocrinology
Impact of urbanisation and altitude on the incidence of, and risk factors for, hypertension.
Bernabé-Ortiz A; Carrillo-Larco RM; Gilman RH; Checkley W; Smeeth L; Miranda JJ; CRONICAS Cohort Study Group; Casas JP; Smith GD; Ebrahim S
2017
Heart (British Cardiac Society)
Study protocol for statin web-based investigation of side effects (StatinWISE): a series of randomised controlled N-of-1 trials comparing atorvastatin and placebo in UK primary care.
Herrett E; Williamson E; Beaumont D; Prowse D; Youssouf N; Brack K; Armitage J; Goldacre B; MacDonald T; Staa TV
2017
BMJ open
Cardiovascular outcomes associated with use of clarithromycin: population based study.
Wong AY; Root A; Douglas IJ; Chui CS; Chan EW; Ghebremichael-Weldeselassie Y; Siu CW; Smeeth L; Wong IC
2016
BMJ (Clinical research ed)
Impact of statin related media coverage on use of statins: interrupted time series analysis with UK primary care data.
Matthews A; Herrett E; Gasparrini A; Van Staa T; Goldacre B; Smeeth L; Bhaskaran K
2016
BMJ (Clinical research ed)
Clinical and Epidemiological Implications of 24-Hour Ambulatory Blood Pressure Monitoring for the Diagnosis of Hypertension in Kenyan Adults: A Population-Based Study.
Etyang AO; Warne B; Kapesa S; Munge K; Bauni E; Cruickshank JK; Smeeth L; Scott JA
2016
Journal of the American Heart Association
The REporting of studies Conducted using Observational Routinely-collected health Data (RECORD) Statement.
Benchimol EI; Smeeth L; Guttmann A; Harron K; Moher D; Petersen I; Sørensen HT; von Elm E; Langan SM; RECORD Working Committee
2015
PLoS medicine
Data Resource Profile: Clinical Practice Research Datalink (CPRD).
Herrett E; Gallagher AM; Bhaskaran K; Forbes H; Mathur R; van Staa T; Smeeth L
2015
International journal of epidemiology
Effect of β blockers on mortality after myocardial infarction in adults with COPD: population based cohort study of UK electronic healthcare records.
Quint JK; Herrett E; Bhaskaran K; Timmis A; Hemingway H; Wedzicha JA; Smeeth L
2013
BMJ (Clinical research ed)
Effect of statins on a wide range of health outcomes: a cohort study validated by comparison with randomized trials
Smeeth L; Douglas I; Hall AJ; Hubbard R; Evans S
2009
British journal of clinical pharmacology
Risk of Myocardial Infarction and Stroke after Acute Infection or Vaccination.
Smeeth L; Thomas SL; Hall AJ; Hubbard R; Farrington P; Vallance P
2004
The New England journal of medicine
MMR vaccination and pervasive developmental disorders: a case-control study.
Smeeth L; Cook C; Fombonne E; Heavey L; Rodrigues LC; Smith PG; Hall AJ
2004
Lancet
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