Close

Mr Matt Silver

Honorary Associate Professor

United Kingdom

Affiliations

MRC Unit The Gambia at LSHTM

Selected Publications

A Pregnancy and Childhood Epigenetics Consortium (PACE) meta-analysis highlights potential relationships between birth order and neonatal blood DNA methylation.
Li, S; Spitz, N; Ghantous, A; Abrishamcar, S; Reimann, B; Marques, I; SILVER, MJ; Aguilar-Lacasaña, S; Kitaba, N; Rezwan, FI; Röder, S; Sirignano, L; Tuhkanen, J; Mancano, G; Sharp, GC; Metayer, C; Morimoto, L; Stein, DJ; Zar, HJ; Alfano, R; Nawrot, T; Wang, C; Kajantie, E; Keikkala, E; Mustaniemi, S; ... Wiemels, JL.
2024
Communications biology
Metastable epialleles in humans.
Derakhshan, M; Kessler, NJ; Hellenthal, G; SILVER, MJ;
2023
Trends in genetics : TIG
Analysis of DNA methylation at birth and in childhood reveals changes associated with season of birth and latitude.
Kadalayil, L; Alam, MZ; White, CH; Ghantous, A; Walton, E; Gruzieva, O; Merid, SK; Kumar, A; Roy, RP; Solomon, O; Huen, K; Eskenazi, B; Rzehak, P; Grote, V; Langhendries, J-P; Verduci, E; Ferre, N; Gruszfeld, D; Gao, L; Guan, W; Zeng, X; Schisterman, EF; Dou, JF; Bakulski, KM; Feinberg, JI; ... Holloway, JW.
2023
Clinical epigenetics
DNA methylation at the suppressor of cytokine signaling 3 (SOCS3) gene influences height in childhood.
ISSARAPU, P; Arumalla, M; Elliott, HR; Nongmaithem, SS; Sankareswaran, A; Betts, M; Sajjadi, S; Kessler, NJ; Bayyana, S; Mansuri, SR; Derakhshan, M; Krishnaveni, GV; Shrestha, S; Kumaran, K; Di Gravio, C; Sahariah, SA; Sanderson, E; RELTON, CL; Ward, KA; Moore, SE; PRENTICE, AM; Lillycrop, KA; Fall, CH D; SILVER, MJ; Chandak, GR; ... EMPHASIS study group,
2023
Nature communications
Early-set POMC methylation variability is accompanied by increased risk for obesity and is addressable by MC4R agonist treatment.
Lechner, L; Opitz, R; SILVER, MJ; Krabusch, PM; PRENTICE, AM; Field, MS; Stachelscheid, H; Leitão, E; Schröder, C; Fernandez Vallone, V; Horsthemke, B; Jöckel, K-H; Schmidt, B; Nöthen, MM; Hoffmann, P; Herms, S; Kleyn, PW; Megges, M; Blume-Peytavi, U; Weiss, K; Mai, K; Blankenstein, O; Obermayer, B; Wiegand, S; Kühnen, P;
2023
Science translational medicine
The influence of early environment and micronutrient availability on developmental epigenetic programming: lessons from the placenta
Sainty, R; SILVER, MJ; PRENTICE, AM; Monk, D;
2023
Frontiers in Cell and Developmental Biology
Tissue- and ethnicity-independent hypervariable DNA methylation states show evidence of establishment in the early human embryo.
Derakhshan, M; Kessler, NJ; Ishida, M; Demetriou, C; Brucato, N; Moore, GE; Fall, CH D; Chandak, GR; Ricaut, F-X; PRENTICE, AM; Hellenthal, G; SILVER, MJ;
2022
Nucleic Acids Research
Environmentally sensitive hotspots in the methylome of the early human embryo.
SILVER, MJ; Saffari, A; Kessler, NJ; Chandak, GR; Fall, CH D; ISSARAPU, P; Dedaniya, A; Betts, M; Moore, SE; Routledge, MN; Herceg, Z; Cuenin, C; Derakhshan, M; James, PT; Monk, D; PRENTICE, AM;
2022
eLife
DNA methylation signatures associated with cardiometabolic risk factors in children from India and The Gambia: results from the EMPHASIS study.
Antoun, E; ISSARAPU, P; Di Gravio, C; Shrestha, S; Betts, M; Saffari, A; Sahariah, SA; Sankareswaran, A; Arumalla, M; PRENTICE, AM; Fall, CH D; SILVER, MJ; Chandak, GR; Lillycrop, KA; EMPHASIS study group,;
2022
Clinical epigenetics
DNA methylation at a nutritionally sensitive region of the PAX8 gene is associated with thyroid volume and function in Gambian children.
Candler, T; Kessler, NJ; Gunasekara, CJ; Ward, KA; James, P; Laritsky, E; Baker, MS; Dyer, R; Elango, R; JEFFRIES, D; Waterland, RA; Moore, SE; Ludgate, M; PRENTICE, AM; SILVER, MJ;
2021
Science Advances
See more information