Close

Professor Anthony Scott

MSc FRCP DTM&H FMedSci

Professor
of Vaccine Epidemiology, Director HPRU in Immunisation

Room
104A

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Tel.
+44 (0) 207 927 2264

I trained in clinical infectious diseases and epidemiology before moving to the KEMRI-Wellcome Trust Research Programme in Kilifi, Kenya in 1993. I have spent most of the last 20 years in Kenya, studying pneumococcal disease and pneumonia in children and adults, and vaccines to prevent them. I am a Wellcome Trust Senior Research Fellow in Clinical Science and I work in clinical paediatrics in Kilifi. I joined the School in 2013 after 15 years based at Oxford University.  In addition to my research I have developed a surveillance network for invasive bacterial diseases in East Africa (Netspear) and I co-direct the Kilifi Health and Demographic Surveillance System. I work frequently with WHO and GAVI on vaccine preventable diseases and with the Ministry of Health in Kenya on the evaluation of pneumococcal vaccine. In the UK I am a member of the Joint Committee on Vaccination and Immunisation (JCVI) and Director of the the NIHR Health Protection Research Unit in Immunisation at LSHTM which involves a portfolio of work on disease burden, vaccine effectiveness, vaccine safety, modelling, cost-effectiveness, vaccine acceptability and policy implementation in collaboration with Public Health England.

Affiliations

Faculty of Epidemiology and Population Health
Department of Infectious Disease Epidemiology

Centres

Vaccine Centre

Teaching

I am co-director of the short course on the Epidemiological Evaluation of Vaccines and teach on the Intensive Course on Epidemiology and Medical Statistics, the MSc Epidemiology and the Diploma course in Tropical Medicine & Hygiene.

Research

My main research interests are in child health and vaccines in East Africa. I run the Pneumcoccal Conjugate Vaccine Impact Study, an effectiveness evaluation of vaccine introduction in Kenya, and a series of associated studies of transmission and modelling of pneumococcal disease, evaluation of vaccine safety, and pathogen population structure. I work with colleagues in Ethiopipa (Hararghe Health Research Partnership) to advance the CHAMPS network project which is coordianted by Emory Global Health Institute. This is a multi-site project designed to estimate cause of death in children using post-mortem tissue biopsies. More broadly, I study the epidemiology of invasive bacterial infections in children and the way that they shape childhood mortality. I am interested in how synthesis of epidemiolgocial evidence supports effective vaccine policy in the UK and how systems for synthesising and modelling epidemiological evidence can advance vaccine policy in low-income countries.

Research Area
Bacteria
Child health
Clinical databases
Diagnostics
Economic evaluation
Surveillance
Vaccines
Global Health
Immunisation
Impact evaluation
Discipline
Immunoepidemiology
Bacteriology
Demography
Epidemiology
Vaccinology
Disease and Health Conditions
Infectious disease
Tuberculosis
Respiratory disease
Sepsis
Country
Kenya
Region
Sub-Saharan Africa (developing only)

Selected Publications

Sustaining pneumococcal vaccination after transitioning from Gavi support: a modelling and cost-effectiveness study in Kenya
Ojal J; Griffiths U; Hammitt LL; Adetifa I; Akech D; Tabu C; Scott A; Flasche S
2019
Lancet Global Health
Effect of Previous Exposure to Malaria on Blood Pressure in Kilifi, Kenya: A Mendelian Randomization Study
Etyang A; Kapesa S; Odipo E; Bauni E; Kyobutungi C; Abdalla M; Muntner P; Musani SK; Macharia A; Williams TN
2019
Journal of the American Heart Association
Causes of severe pneumonia requiring hospital admission in children without HIV infection from Africa and Asia: the PERCH multi-country case-control study
O'Brien K; Levine OS; Scott A; Deloria Knoll M; Feikin DR; DeLuca AN; Driscoll AJ; Fancourt N; Fu W; Haddix M
2019
Lancet
Effect of strikes by health workers on mortality between 2010 and 2016 in Kilifi, Kenya: a population-based cohort analysis
Ong'ayo G; Ooko M; Wang'odu R; Bottomley C; Nyaguara C; Tsofa B; Williams T; Bejon P; Scott A; Etyang A
2019
The Lancet Global Health
Risk of nontyphoidal Salmonella bacteraemia in African children is modified by STAT4.
Gilchrist JJ; Rautanen A; Fairfax BP; Mills TC; Naranbhai V; Trochet H; Pirinen M; Muthumbi E; Mwarumba S; Njuguna P
2018
Nature communications
Prospective Observational Study of Incidence and Preventable Burden of Childhood Tuberculosis, Kenya.
Brent AJ; Nyundo C; Langat J; Mulunda C; Wambua J; Bauni E; Sande J; Park K; Williams TN; Newton CRJ
2018
Emerging infectious diseases
Effect of ten-valent pneumococcal conjugate vaccine on invasive pneumococcal disease and nasopharyngeal carriage in Kenya: a longitudinal surveillance study
Hammitt LL; Etyang A; Morpeth SC; Ojal J; Mutuku A; Mturi N; Moisi JC; Adetifa IM; Karani A; Akech DO
2018
Lancet
Assessing the efficiency of catch-up campaigns for the introduction of pneumococcal conjugate vaccine: a modelling study based on data from PCV10 introduction in Kilifi, Kenya.
Flasche S; Ojal J; Le Polain de Waroux O; Otiende M; O'Brien KL; Kiti M; Nokes DJ; Edmunds WJ; Scott JAG
2017
BMC medicine
See more Publications