Dr Corine Ngufor
Associate Professor
CREC/LSHTM Collaborative Research Programme
CREC/LSHTM Laboratory
Cotonou
Benin
Corine Ngufor is Associate Professor of medical entomology at LSHTM with several years of field experience in mosquito biology and vector control. She holds a Masters in the Biology and Control of Disease Vectors and a PhD in medical entomology both from LSHTM. Her PhD focused on the use of insecticide combinations to improve the control and management of insecticide resistant African malaria vectors. Corine started working at LSHTM in 2011 supervising and coordinating several WHO Phase I and II vector control studies across sub-saharan Africa (Tanzania, Cote D'Ivoire, Burkina Faso and Benin). She is currently based in Benin since 2013 where she is lead scientist and manager of the GLP-certified CREC/LSHTM Collaborative Research Programme (www.crec-lshtm.org) implementing a large portfolio of vector control projects investigating new vector control tools for targeting insecticide resistant malaria vectors in WHO laboratory, semi-field and randomised controlled trials. Beyond vector control, Corine is Principal Investigator of the UNITAID funded Plus project for Benin evaluating the implementation and impact of perennial malaria chemoprevention in Benin and the USAID funded MaCRA project investigating the reporting of malaria RDTs in public health facilities in Benin. She is a member of the Vector Control Advisory Group (VCAG) and Malaria Policy Advisory Group (MPAG) of the World Health Organisation, co-chair of the Vector Control Working Group of the Roll Back Malaria partnership and a member of the External Scientific Advisory Committee (ESAC) of the Innovative Vector Control Consortium (IVCC).
Affiliations
Centres
Teaching
1. Teaching on LSHTM MSc modules:
- 2017-Present: LSHTM distance Learning module in Malaria (IDM503): Updated course materials on vector control and marking of assignments.
2. 2021 - Present: LSHTM Module 3196: Integrated Vector Management (2021): Lecturing on vector control product evaluation
3. 2017-Present: LSHTM Module 9195: Malaria: from science to policy and practice. Tutoring students and marking of assignments.
2. Supervising Masters students from LSHTM for summer projects in Benin
LSHTM MSc students (14 completed):
1. Benjamin Pearce LSHTM (2024): An Experimental Hut Trial to Assess the Impact of Combining Insecticide-Treated Nets with Transfluthrin Passive Emanators for Improved Malaria Vector Control in Benin
2. Isabelle Obrien LSHTM (2023): Impact of indoor residual spraying on malaria burden in communities in Southern Benin
3. Aswathy Hariharan- LSHTM (2023): Impact of fabric type on ITN efficacy and householder’s preference and perception of ITNs in Southern Benin
4. Jamsin Panzid-Foster LSHTM (2023): Experimental hut evaluation of the efficacy of two mosquito traps for sampling malaria vectors in Southern Benin
5. Harry Pollard – LSHTM (2022): An experimental hut trial to evaluate the entomological impact of combining a pyrethroid-chlorfenapyr mixture net with different types of next-generation indoor residual spraying insecticide
6. Alexis Schneider – LSHTM (2022): Experimental hut evaluation of the efficacy and wash resistance of a new alphacypermethrin and chlorfenapyr mixture bed nets against wild malaria vectors in Covè, Benin: a non-inferiority assessment
7. Alesha Myers – LSHTM (2022), Optimising methods for investigating resistance to pyriproxyfen in wild malaria vectors
8. Kathleen Varvera LSHTM (2022): Determining the diagnostic dose for monitoring resistance to broflanilide in mosquito vectors
9. Colette Morlinho – LSHTM (2022): Land use and spatial distribution of malaria transmission in the Cove-Ouinhi-Zagnanando districts of Southern Benin: a cross sectional study
10. Dorothy Obuobi - LSHTM (2019): Comparing the efficacy of piperonyl butoxide-pyrethroid long lasting insecticidal nets in combination with different types of indoor residual spraying insecticides
11. Thomas Syme - LSHTM (2018): Comparing the efficacy of standard pyrethroid LLINs in combination with different types of IRS insecticides
12. Alex Wilson - LSHTM (2018): Investigating the intensity of pyrethroid resistance in the An gambiae sl population at the experimental hut station in Cove, Zou District, Benin
13. Rhodri Edwards-LSHTM, (2017): A modified design of the West African experimental huts for improved evaluation of vector control products
14. Jessica Critchley-LSHTM (2015): Comparing the efficacy of insecticide mixtures on bed nets or indoor residual spraying to combined non-pyrethroid IRS and pyrethroid bed net intervention; an experimental hut study in Central Benin
7. Supervising Masters Students from University of Abomey Calavi, Benin
University of Abomey Calavi MSc students (8 completed):
1. Georgine Houetohousso-UAC (2021): Investigating methods for measuring the fertility of mosquitoes exposed to pyriproxyfen treated nets
2. Riliwanou Issiakou – UAC (2021): Infectivity and insecticide resistance status of malaria vectors in the Zakpota subdistrict of Benin.
3. Eupharasie Obossou-UAC (2021): Insecticide resistance profile of malaria vectors maintained at the CREC-LSHTM insectary for the evaluation of vector control products.
4. Agossou Nina- UAC (2024): Evaluation of malaria RDTs for the diagnosis of pregnant women in the Bohicon health centre in Benin
5. Godwin Ahokpe, UAC (2024): Comparative diagnosis of malaria (RDT vs Microscopy vs PCR) for patients visiting health facilities in Benin.
6. Koudebi Sidonie (2024): Evaluating the VectorCAM app for the identification of malaria vectors in Benin
7. Jocelyn Taco UAC (2024): Impact of pre-exposure to pyriproxyfen on the susceptibility of pyrethroid resistant malaria vectors to various pyrethroid insecticides
8. Eloe Tantoukoute, UAC (2024): Investigating the synergistic effect of PBO on bendiocarb for improved control of carbamate-resistant malaria vectors
8. Developed training manuals and organized and delivered several training courses on laboratory and field evaluation of vector control products to Good Laboratory Practice for staff of Centre de Recherche Entomologique de Cotonou, Benin (2017-present)
Research
Corine's primary research interest is in the development and evaluation of new vector control tools for improved control and management of insecticide resistant disease vectors of malaria and arboviruses. Corine is the manager and lead scientist of a GLP-certified Facility in Benin which generates high quality efficacy data for vector control product registration to WHO standards. Corine evaluates several types of vector control products mostly LLINs, IRS, repellents, ATSB, larvicides etc in laboratory Phase I studies, Semi-field Phase trials, community Phase III studies and community randomized trials. Corine also performs studies to explore ways in which new vector control products can be optimally deployed in combinations, in sequence etc to maximize their potential for improved vector control and insecticide resistance management.
She is currently the Principal Investigator of several vector control research projects in Benin including a large-scale community trials evaluating the efficacy of VECTRON T500, a newly developed IRS products for malaria vector control and for the UNITAID-funded large scale community randomised trials to assess the durability of newly developed dual AI insecticide treated nets (New Net Project) . She is also leading several other malaria research projects in Benin such as the PMI Insights project (MaCRA) investigating the interpretation and reporting of malaria RDTs in Benin and the UNITAID-funded Plus project study evaluating the impact of perennial malaria chemoprevention (PMC) in Benin.
Training post doctoral/early career researchers:
Current postdocs:
- Dr Idelphonse Ahogni, CREC, Investigating the reporting of malaria RDTs in public health facilities in Benin (2022-2026)
- Dr N'Tcha Ludovic, CREC, Investigating social determinants of coverage of perrenial malaria chemoprevention in Benin (2022-2025)
- Dr Azizath Moussiliou, CREC, Mapping of resistance to SP to inform deployment of PMC in Benin (2022-2025)
Previous postdocs:
- Dr Renaud Govoetchan, LSHTM - Investigating the efficacy of novel vector control products in laboratory, semi-field and community trials (2018-2024)
Supervising PhD Students:
Current PhD students:
- Thomas Syme (2020 - 2025) - London School of Hygiene & Tropical Medicine – Primary Supervisor
- Boris N'dombidge (2024 - 2028) - University of Abomey - Primary Supervisor
- Abel Agbevo, (2021- 2025) London School of Hygiene & Tropical Medicine- Primary Supervisor,
- Josias Fagbohoun, (2023 - 2027) University of Abomey Calavi, Benin – Second Supervisor
Completed PhD students:
- Augustin Fongnikin (2016-2022) - Abomey Calavi University in Benin – Second supervisor
Member of advisory committee and viva panel of PhD students:
- 2020-2024: Jackline Martin, London School of Hygiene & Tropical Medicine
- 2017-2021: Janneke Snetselaar, London School of Hygiene & Tropical Medicine
- 2022 - PhD examiner, viva panel member - Katherin Gleave, Liverpool School of Tropical Medicine
Selected Publications
