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Professor Serge Mostowy

Professor
of Cellular Microbiology

Room
Rm186

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Tel.
+44 (0) 207 927 2600

Serge is a Lister Institute of Preventive Medicine, Wellcome Beit and Wellcome Trust Senior Research Fellow. He studied Physics (BSc), Evolution (MSc) and Microbiology & Immunology (PhD) at McGill University in Canada. After postdoctoral work on the Cell Biology of Infection at Institut Pasteur in France, he moved to Imperial College London in 2012 to start a Wellcome Trust Research Career Development Fellowship. In 2018 Serge was appointed Professor of Cellular Microbiology at the London School of Hygiene & Tropical Medicine, where his lab investigates novel roles for the cytoskeleton in innate immunity. The Mostowy lab has also developed the zebrafish as an important model to study the cell biology of infection and therapeutic potential of targeting the cytoskeleton in vivo.

Awards and Honors

  • ERC Consolidator Grant (2019)
  • Wellcome Trust Senior Research Fellowship (2018)
  • Lister Research Institute Prize Fellowship (2015)
  • Wellcome Trust Large Arts Award (2014)
  • Wellcome Beit Research Fellowship (2012)
  • Wellcome Trust Research Career Development Fellowship (2012)

Affiliations

Faculty of Infectious and Tropical Diseases
Department of Infection Biology

Research

Discipline
Cell biology
Microbiology

Selected Publications

Pyroptosis in host defence against bacterial infection.
Brokatzky D; Mostowy S
2022
Disease Models and Mechanisms
P1 bacteriophage-enabled delivery of CRISPR-Cas9 antimicrobial activity against <i>Shigella flexneri</i>
Huan YW; Torraca V; Brown R; Fa-arun J; Miles SL; Oyarzún DA; Mostowy S; Wang B
2022
Cold Spring Harbor Laboratory
An automated microscopy workflow to study Shigella-neutrophil interactions and antibiotic efficacy in vivo
Lensen A; Gomes MC; López-Jiménez AT; Mostowy S
2022
Cold Spring Harbor Laboratory
Septins promote caspase activity and coordinate mitochondrial apoptosis.
Van Ngo H; Robertin S; Brokatzky D; Bielecka MK; Lobato-Márquez D; Torraca V; Mostowy S
2022
Cytoskeleton
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)<sup>1</sup>.
Klionsky DJ; Abdel-Aziz AK; Abdelfatah S; Abdellatif M; Abdoli A; Abel S; Abeliovich H; Abildgaard MH; Abudu YP; Acevedo-Arozena A
2021
Autophagy
Mechanistic insight into bacterial entrapment by septin cage reconstitution.
Lobato-Márquez D; Xu J; Güler GÖ; Ojiakor A; Pilhofer M; Mostowy S
2021
Nature communications
Emerging technologies and infection models in cellular microbiology.
López-Jiménez AT; Mostowy S
2021
Nature communications
Defects in <i>LC3B2</i> and <i>ATG4A</i> underlie HSV2 meningitis and reveal a critical role for autophagy in antiviral defense in humans.
Hait AS; Olagnier D; Sancho-Shimizu V; Skipper KA; Helleberg M; Larsen SM; Bodda C; Moldovan LI; Ren F; Brinck Andersen N-S
2020
Science immunology
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