Dr Michael Marks

MRCP DTM&H PhD

Assistant Professor

Room

359

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

I am an NIHR Clinical Lecturer in infectious diseases and general medicine. My Phd, which was funded by the Wellcome Trust, focused on understanding the impact of azithromycin mass administration on treponemal infections as part of a strategy to eliminate yaws in the Solomon Islands including work on disease mapping and the evaluation of diagnostic tests. I am also involved in trials on the treatment of yaws in Ghana and Papua New Guinea and studies using sequencing to understand treponemal diversity. Alongside this I have an interest in the epidemiology and control of scabies, which is endemic in the Pacific region and has recently been adopted as an NTD by the World Health Organization. Alongside my work on these two specific NTDs I am involved in studies on integrated approaches to the management of neglected tropical diseases.

Following my PhD my research interests have expanded to include all of the human treponematoses including both Treponema pallidum subsp. pallidum (the causative agent of syphilis) whilst continuing my interest in T.pallidum subsp. pertenue (the causative agent of yaws). I collaborate with Professor Nick Thomson on the application of next-generation sequencing tools to our understanding in these important diseases.

Details of grants and work I have been involved in are also available on ORC-ID

Alongside my research work at LSHTM, I worked with Chrissy Roberts to establish and run the ODK@LSHTM service which supports the uptake of the ODK electronic data collection platform in research projects run by LSHTM worldwide.

Affiliations

Faculty of Infectious and Tropical Diseases

Department of Clinical Research

Teaching

I am the deputy module director of the recently established Neglected Tropical Diseases MSc module. I teach on both the London Diploma in Tropical Medicine and Hygiene (DTM&H) and the East African DTM&H (LSHTM). I am also a tutor on the malaria module for the MSc Infectious Diseases by Distance Learning (LSHTM).

Research

Yaws: Epidemiology, community treatment strategies, diagnostics and modelling
Scabies: Epidemiology, community treatment strategies
NTDs: Integrated Case Finding & Mass Drug Administration Strategies
Treponema pallidum: Sequencing, host-pathogen interactions

Research Area

Clinical care

Diagnostics

Infectious disease policy

Sexual health

Disease control

Global Health

Impact evaluation

Mobile technologies

Implementation research

Randomised controlled trials

Discipline

Bacteriology

Epidemiology

Medicine

Microbiology

Mathematical modelling

Disease and Health Conditions

Syphilis

Infectious disease

Trachoma

Emerging Infectious Disease

Neglected Tropical Diseases (NTDs)

Sexually transmitted infection

Skin disease

Tropical diseases

Country

Ghana

Liberia

Papua New Guinea

Solomon Islands

Vanuatu

Region

Pacific island small states

Sub-Saharan Africa (developing only)

Selected Publications

Comparative efficacy of low-dose versus standard-dose azithromycin for patients with yaws: a randomised non-inferiority trial in Ghana and Papua New Guinea.

Marks, M. ; Mitjà, O. ; Bottomley, C. ; Kwakye, C. ; Houinei, W. ; Bauri, M. ; Adwere, P. ; Abdulai, A.A. ; Dua, F. ; Boateng, L. ; Wangi, J. ; Ohene, S.A. ; Wangnapi, R. ; Simpson, S.V. ; Miag, H. ; Addo, K.K. ; Basing, L.A. ; Danavall, D. ; Chi, K.H. ; Pillay, A. ; Ballard, R. ; Solomon, A.W. ; Chen, C.Y. ; Bieb, S.V. ; Adu-Sarkodie, Y. ; Mabey, D.C.W. ; Asiedu, K. ; study team, . ; COLLABORATORS;Marks, M. ; Mitjà, O. ; Bottomley, C. ; Kwakye, C. ; Hounei, W. ; Bauri, M. ; Adwere, P. ; Abdulai, A.A. ; Dua, F. ; Boateng, L. ; Wangi, J. ; Ohene, S.A. ; Wangnapi, R. ; Simpson, S.V. ; Miag, H. ; Addo, K.K. ; Basing, L.A. ; Danavall, D. ; Chi, K.H. ; Pillay, A. ; Ballard, R. ; Solomon, A.W. ; Chen, C.Y. ; Bieb, S.V. ; Adu-Sarkodie, Y. ; Mabey, D.C. ; Asiedu, K. ; Agana, N. ; Ampadu, E. ; Amponsah-Achiano, K. ; Bediako, A. ; Biredu, M. ; Faried, K. ; Iddrisu, A. ; Kotey, N.K. ; Yeboah, G.N. ; El-Duah, P. ; Phillips, R. ; Binka, F. ; Nyonator, F. ; Zunuo, A. ; Ackumey, M.A. ; Amanor, I. ; Bnosu, C. ; Frischmann, S. ; Lammie, P. ; Martin, D. ; Ye, T. ; Christophel, E. ; Tiendrebeogo, A. ; Vestergard, L. ; Bassat, Q. ; Abdad, Y. ; Dima, H. ; Kotty, B. ; Mamore, K. ; Manup, W. ; Olowau, B. ; Agyei, E.O. ; Agyemang, D. ; Ako, E.P. ; Antwi, P. ; Darko, J. ; Darko, O.O. ; Darko, P. ; Duodu, B. ; Jabasi, D. ; Karim, F.L. ; Koomson, O.K. ; Labri, B.A. ; Nartey, J. ; Tamatey, R. ; Yirenkyi, B. ; Arhin, M. ; Biney, F. ; Danso, J.O. ; Dei, M.A. ; Djan, M. ; Sasu, S. ; Solomon, B.A. ; Torvinya, V. ; Amankwaah, H. ; Baffoe, J. ; Djan, M. ; Keteku, L. ; Kondobala, K. ; Lomotey, R.D. ; Nartey, A.A. ; Oppong, P. ; Quainoo, M.A. ; Abotsi, T. ; Agebshie, D. ; Ameamu, A. ; Angwaawie, P. ; Ayibor, R. ; Mwingmendeli, M. ; Nakodia, J. ; Nambagyira, A. ; Nanga, D. ; Tetteh, N. ; Wanaom, A. ;

2018

Lancet Glob Health

Mathematical Modeling of Programmatic Requirements for Yaws Eradication.

Marks, M. ; Mitjà, O. ; Fitzpatrick, C. ; Asiedu, K. ; Solomon, A.W. ; Mabey, D.C. ; Funk, S. ;

2017

Emerg Infect Dis

Diagnostics for yaws eradication: insights from direct next generation sequencing of cutaneous strains of Treponema pallidum.

Marks, M. ; Fookes, M. ; Wagner, J. ; Butcher, R. ; Ghinai, R. ; Sokana, O. ; Sarkodie, Y.A. ; Lukehart, S.A. ; Solomon, A.W. ; Mabey, D.C.W. ; Thomson, N. ;

2017

Clin Infect Dis

Meta-analysis of the performance of a combined treponemal and non-treponemal rapid diagnostic test for syphilis and yaws.

Marks, M.; Yin, Y.P.; Chen, X.S.; Castro, A.; Causer, L.; Guy, R.; Wangnapi, R.; Mitjà, O.; Aziz, A.; Castro, R.; da Luz Martins Pereira, F.; Taleo, F.; Guinard, J.; Bélec, L.; Tun, Y.; Bottomley, C.; Ballard, R.C.; Mabey, D.C.;

2016

Clin Infect Dis

A cross-sectional study of 'yaws' in districts of ghana which have previously undertaken azithromycin mass drug administration for trachoma control.

Ghinai, R. ; El-Duah, P. ; Chi, K.H. ; Pillay, A. ; Solomon, A.W. ; Bailey, R.L. ; Agana, N. ; Mabey, D.C. ; Chen, C.Y. ; Adu-Sarkodie, Y. ; Marks, M. ;

2015

PLoS Negl Trop Dis

Global epidemiology of yaws: a systematic review.

Mitjà, O. ; Marks, M. ; Konan, D.J. ; Ayelo, G. ; Gonzalez-Beiras, C. ; Boua, B. ; Houinei, W. ; Kobara, Y. ; Tabah, E.N. ; Nsiire, A. ; Obvala, D. ; Taleo, F. ; Djupuri, R. ; Zaixing, Z. ; Utzinger, J. ; Vestergaard, L.S. ; Bassat, Q. ; Asiedu, K. ;

2015

Lancet Glob Health

Challenges and key research questions for yaws eradication.

Marks, M.; Mitjà, O.; Vestergaard, L.S.; Pillay, A.; Knauf, S.; Chen, C.Y.; Bassat, Q.; Martin, D.L.; Fegan, D.; Taleo, F.; Kool, J.; Lukehart, S.; Emerson, P.M.; Solomon, A.W.; Ye, T.; Ballard, R.C.; Mabey, D.C.; Asiedu, K.B.;

2015

Lancet Infect Dis

Haemophilus ducreyi Associated with Skin Ulcers among Children, Solomon Islands.

Marks, M. ; Chi, K.H. ; Vahi, V. ; Pillay, A. ; Sokana, O. ; Pavluck, A. ; Mabey, D.C. ; Chen, C.Y. ; Solomon, A.W. ;

2014

Emerg Infect Dis

See all Dr Michael Marks's Publications

Dr Michael Marks

MRCP DTM&H PhD

Assistant Professor

Affiliations

Teaching

Research

Selected Publications

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