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Dr Michael Marks

MRCP DTM&H PhD

Assistant Professor

Room
359

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

I am an NIHR Clinical Lecturer in infectious diseases. My Phd, which was funded by the Wellcome Trust, focused on understanding the impact of azithromycin mass administration on treponemal infections as part of a strategy to eliminate yaws in the Solomon Islands including work on disease mapping and the evaluation of diagnostic tests. I was a lead investigator on a WHO sponsored trial of treatment of yaws in Ghana and Papua New Guinea and collaborate with Oriol Mitjà on studies to optimise community treatment strategies for yaws in PNG.

Following my PhD my research interests have expanded to include all of the human treponematoses including both Treponema pallidum subsp. pallidum (the causative agent of syphilis) whilst continuing my interest in T.pallidum subsp. pertenue (the causative agent of yaws). I collaborate with Professor Nick Thomson on the application of next-generation sequencing tools to our understanding in these important diseases.

I am involved in a number of studies on the the epidemiology and control of scabies, which is endemic in the Pacific region and has recently been adopted as an NTD by the World Health Organization. I collaborate with Andrew Steer, in Melbourne, and John Kaldor, in Sydney, on a number of studies to better understand the use of mass treatment strategies to control scabies in endemic communities.

As well as work on these specific NTDs I am interested in strategies for the integrated control of neglected tropical diseases. I am a lead investigator on several studies exploring the possibility of combining MDA programmes for multiple NTDs into a single intervention in Ethiopia and Papua New Guinea and work with Rachel Pullan's group on integrated case-finding for NTDs in Liberia.

 

Details of grants and work I have been involved in are also available on ORC-ID

Alongside my research work at LSHTM, I worked with Chrissy Roberts to establish and run the ODK@LSHTM service which supports the uptake of the ODK electronic data collection platform in research projects run by LSHTM worldwide.

Affiliations

Department of Clinical Research
Faculty of Infectious and Tropical Diseases

Teaching

I am the deputy module director of the recently established Neglected Tropical Diseases MSc module. I teach on both the London Diploma in Tropical Medicine and Hygiene (DTM&H) and the East African DTM&H (LSHTM). I am also a tutor on the malaria module for the MSc Infectious Diseases by Distance Learning (LSHTM).

Research

  • Yaws: Epidemiology, community treatment strategies, diagnostics and modelling
  • Scabies: Epidemiology, community treatment strategies
  • NTDs: Integrated Case Finding & Mass Drug Administration Strategies
  • Treponema pallidum: Sequencing, host-pathogen interactions
Research Area
Clinical care
Diagnostics
Infectious disease policy
Sexual health
Disease control
Global Health
Impact evaluation
Mobile technologies
Implementation research
Randomised controlled trials
Discipline
Bacteriology
Epidemiology
Medicine
Microbiology
Mathematical modelling
Disease and Health Conditions
Syphilis
Infectious disease
Trachoma
Emerging Infectious Disease
Neglected Tropical Diseases (NTDs)
Sexually transmitted infection
Skin disease
Tropical diseases
Country
Ghana
Gambia, The
Liberia
Papua New Guinea
Solomon Islands
Vanuatu
Region
Pacific island small states
Sub-Saharan Africa (developing only)

Selected Publications

Comparative efficacy of low-dose versus standard-dose azithromycin for patients with yaws: a randomised non-inferiority trial in Ghana and Papua New Guinea.
Marks, M. ; Mitjà, O. ; Bottomley, C. ; Kwakye, C. ; Houinei, W. ; Bauri, M. ; Adwere, P. ; Abdulai, A.A. ; Dua, F. ; Boateng, L. ; Wangi, J. ; Ohene, S.A. ; Wangnapi, R. ; Simpson, S.V. ; Miag, H. ; Addo, K.K. ; Basing, L.A. ; Danavall, D. ; Chi, K.H. ; Pillay, A. ; Ballard, R. ; Solomon, A.W. ; Chen, C.Y. ; Bieb, S.V. ; Adu-Sarkodie, Y. ; Mabey, D.C.W. ; Asiedu, K. ; study team, . ; COLLABORATORS;Marks, M. ; Mitjà, O. ; Bottomley, C. ; Kwakye, C. ; Hounei, W. ; Bauri, M. ; Adwere, P. ; Abdulai, A.A. ; Dua, F. ; Boateng, L. ; Wangi, J. ; Ohene, S.A. ; Wangnapi, R. ; Simpson, S.V. ; Miag, H. ; Addo, K.K. ; Basing, L.A. ; Danavall, D. ; Chi, K.H. ; Pillay, A. ; Ballard, R. ; Solomon, A.W. ; Chen, C.Y. ; Bieb, S.V. ; Adu-Sarkodie, Y. ; Mabey, D.C. ; Asiedu, K. ; Agana, N. ; Ampadu, E. ; Amponsah-Achiano, K. ; Bediako, A. ; Biredu, M. ; Faried, K. ; Iddrisu, A. ; Kotey, N.K. ; Yeboah, G.N. ; El-Duah, P. ; Phillips, R. ; Binka, F. ; Nyonator, F. ; Zunuo, A. ; Ackumey, M.A. ; Amanor, I. ; Bnosu, C. ; Frischmann, S. ; Lammie, P. ; Martin, D. ; Ye, T. ; Christophel, E. ; Tiendrebeogo, A. ; Vestergard, L. ; Bassat, Q. ; Abdad, Y. ; Dima, H. ; Kotty, B. ; Mamore, K. ; Manup, W. ; Olowau, B. ; Agyei, E.O. ; Agyemang, D. ; Ako, E.P. ; Antwi, P. ; Darko, J. ; Darko, O.O. ; Darko, P. ; Duodu, B. ; Jabasi, D. ; Karim, F.L. ; Koomson, O.K. ; Labri, B.A. ; Nartey, J. ; Tamatey, R. ; Yirenkyi, B. ; Arhin, M. ; Biney, F. ; Danso, J.O. ; Dei, M.A. ; Djan, M. ; Sasu, S. ; Solomon, B.A. ; Torvinya, V. ; Amankwaah, H. ; Baffoe, J. ; Djan, M. ; Keteku, L. ; Kondobala, K. ; Lomotey, R.D. ; Nartey, A.A. ; Oppong, P. ; Quainoo, M.A. ; Abotsi, T. ; Agebshie, D. ; Ameamu, A. ; Angwaawie, P. ; Ayibor, R. ; Mwingmendeli, M. ; Nakodia, J. ; Nambagyira, A. ; Nanga, D. ; Tetteh, N. ; Wanaom, A. ;
2018
Lancet Glob Health
Mathematical Modeling of Programmatic Requirements for Yaws Eradication.
Marks, M. ; Mitjà, O. ; Fitzpatrick, C. ; Asiedu, K. ; Solomon, A.W. ; Mabey, D.C. ; Funk, S. ;
2017
Emerg Infect Dis
Diagnostics for yaws eradication: insights from direct next generation sequencing of cutaneous strains of Treponema pallidum.
Marks, M. ; Fookes, M. ; Wagner, J. ; Butcher, R. ; Ghinai, R. ; Sokana, O. ; Sarkodie, Y.A. ; Lukehart, S.A. ; Solomon, A.W. ; Mabey, D.C.W. ; Thomson, N. ;
2017
Clin Infect Dis
Meta-analysis of the performance of a combined treponemal and non-treponemal rapid diagnostic test for syphilis and yaws.
Marks, M.; Yin, Y.P.; Chen, X.S.; Castro, A.; Causer, L.; Guy, R.; Wangnapi, R.; Mitjà, O.; Aziz, A.; Castro, R.; da Luz Martins Pereira, F.; Taleo, F.; Guinard, J.; Bélec, L.; Tun, Y.; Bottomley, C.; Ballard, R.C.; Mabey, D.C.;
2016
Clin Infect Dis
A cross-sectional study of 'yaws' in districts of ghana which have previously undertaken azithromycin mass drug administration for trachoma control.
Ghinai, R. ; El-Duah, P. ; Chi, K.H. ; Pillay, A. ; Solomon, A.W. ; Bailey, R.L. ; Agana, N. ; Mabey, D.C. ; Chen, C.Y. ; Adu-Sarkodie, Y. ; Marks, M. ;
2015
PLoS Negl Trop Dis
Global epidemiology of yaws: a systematic review.
Mitjà, O. ; Marks, M. ; Konan, D.J. ; Ayelo, G. ; Gonzalez-Beiras, C. ; Boua, B. ; Houinei, W. ; Kobara, Y. ; Tabah, E.N. ; Nsiire, A. ; Obvala, D. ; Taleo, F. ; Djupuri, R. ; Zaixing, Z. ; Utzinger, J. ; Vestergaard, L.S. ; Bassat, Q. ; Asiedu, K. ;
2015
Lancet Glob Health
Challenges and key research questions for yaws eradication.
Marks, M.; Mitjà, O.; Vestergaard, L.S.; Pillay, A.; Knauf, S.; Chen, C.Y.; Bassat, Q.; Martin, D.L.; Fegan, D.; Taleo, F.; Kool, J.; Lukehart, S.; Emerson, P.M.; Solomon, A.W.; Ye, T.; Ballard, R.C.; Mabey, D.C.; Asiedu, K.B.;
2015
Lancet Infect Dis
Haemophilus ducreyi Associated with Skin Ulcers among Children, Solomon Islands.
Marks, M. ; Chi, K.H. ; Vahi, V. ; Pillay, A. ; Sokana, O. ; Pavluck, A. ; Mabey, D.C. ; Chen, C.Y. ; Solomon, A.W. ;
2014
Emerg Infect Dis
See all Dr Michael Marks's Publications