Professor James Logan
Bsc PhD FRES
Head of the Department of Disease Control and Director of ARCTEC
James is the Head of the Department of Disease Control and Director of the Arthropod Control Product Test Centre (ARCTEC). He is Principal Investigator of a large research portfolio investigating novel ways to control arthropod vectors that transmit pathogens of medical importance, including Zika, malaria and dengue. James ia the UK's leading expert on insect repellents and methods of personal protection against arthropod vectors. Through chemical ecology studies, his research group explores the complex interaction between arthropod vectors, vertebrate hosts and pathogens at the behavioural, olfactory and molecular level. The Logan group also investigates the mode of action of new (and current) monitoring and control technologies for arthropods, using in-house state-of-the-art experimental equipment including electroantennography, single sensillum recording, gas chromatography, RT-PCR and behavioural olfactometry, as well as Category 3 facilities which allow complex malaria infection studies with Anopheles gambiae mosquitoes and Plasmodium falciparum parasites. The arctec laboratories, and well-stocked insectaries, house excellent facilities for the development and high-throughput evaluation of arthropod-related products and technologies for pest and vector control.
James' lab is Good Laboratory Practice (GLP)-compliant and the team is GCP-trained and highly practiced in coordinating clinical trials on commercial products including repellents, after-bite treatments and head lice treatments.
James began his career with a first class BSc honours degree in Zoology from the University of Aberdeen in 2001 and an award-winning PhD in 2005. He then led a research group at Rothamsted Research, as Senior Postdoctoral Research Scientist, within the Chemical Ecology Programme, before joining the School.
James is the Founder of two spin out companies: ARTCEC and Vecotech Ltd.
James is a Fellow of the Royal Entomological Society, Chair of the Public Engagement Committee and a member of the Innovations Committee.
James is an avid science communicator and is Science Ambassador for the Science Technology Engineering and Mathematics Network (STEMNET) which aims to inspire young people in science. James is also a science TV presenter, currently working on exciting programmes with the BBC and Channel 4. He also makes regular appearances on television, radio and in print media as a scientific expert.
James enjoys taking part in charity work and is a Patron of Medical Aid Films, which uses innovative media to transform the health and wellbeing of women and children around the world.
James is Lead Educator for the free online course on Zika and another on Vector Control (MOOC). He is also Module Organiser of the Integrated Vector Management Module and the residential field trip for entomology and parasitology for the MSc course, Biology and Control of Disease Vectors. He teaches on several other MSc courses including Medical Parasitology, Control of Infectious Diseases, Tropical Medicine and International Health, Diploma in Tropical Medicine & Hygiene and the Short Course on Travel Medicine. James also supervises several PhD projects and MSc summer projects.
Logan Research Group
The Logan research group investigates novel ways to control arthropod vectors that transmit pathogens of human and animal diseases in the UK and overseas by exploring:
- the interaction between arthropods, animal/human hosts and pathogens at the olfactory and behavioural level
- aspects of insect ecology including aggregation, mating and oviposition in a variety of arthropods
- the mode of action of new (and current) monitoring and control techniques
- the development of new or improved control technologies
The Logan laboratories are equipped with state-of-the-art experimental facilities including electroantennography, single sensillum recording, gas chromatography, RT-PCR and behavioural olfactometry, as well as Category 3 facilities which allow complex malaria infection studies with Anopheles gambiae mosquitoes and Plasmodium falciparum parasites. This integrated approach gives a better understanding of how arthropods use semiochemicals naturally and how they can be exploit them to develop control strategies through behavioural manipulation. Ultimately, the aim is to attain effective control using semiochemicals that will allow more targeting use of control agents such as insecticides.
Current research projects:
- Wearable technologies for protection against Zika vectors (EU H2020)
- The Global Vector Hub - building a community of practice for researchers interested in vector control, with a focus on Zika (EU and BBSRC)
- GenoScent: genetic mechanisms underlying the production of natural repellents by the human body (MRC)
- Olfactory mechanisms underlying behavioural manipulation of mosquitoes by malaria parasites (BBSRC funded)
- Chemical signalling of malaria parasites: call for transmission? (ZonMw funded)
- StrongerSAFE: development of novel tools to control the trachoma vector, Musca sorbens
- Identification and development of novel repellents from human odours
- Development of novel control methods for bed bugs and identification of bed bug aggregation pheromones
Current PhD studentships:
- Evaluation of an Aedes-control intervention scaled- up under an intersectoral approach in a hyper-endemic municipality in Colombia (Juliana Quintero)
- Microbiomics and genetics of human attractiveness to malaria mosquitoes (Alicia Showering, MRC)
An investigation into the role of the skin odorants and microbiota in the
attraction of malaria mosquitoes to human beings. (Christina Due, BBSRC Industrial Case, Unilever)
Arthropod Control Product Test Centre (arctec)
The Arthropod Control Product Test Centre (arctec) has an outstanding reputation as a world leading independent testing house for the development and evaluation of commercial products including repellents, insecticides, head lice treatments and after-bite treatments. Our highly skilled scientists and rigorous protocols ensure that we remain one of the most reputable and competitive institutions for the testing of arthropod control products in the world.
The arctec laboratories are GLP compliant and house excellent facilities for the development and high-throughput evaluation of arthropod-related products and technologies. The scientific and coordination teams are GCP-trained and highly practiced in coordinating clinical trials on medicinal and non-medicinal commercial products.
Visit our website at http://arctec.lshtm.ac.uk