Katherine's research aims to quantify, understand, and address barriers to tuberculosis (TB) prevention and care. As an epidemiologist and mathematical modeller, she focuses on generating quantitative evidence to inform policy and practice. Her current research interests include gender and other social determinants, early and asymptomatic disease, community screening, and trial design.

She is the LSHTM Principal Investigator and Consortium Modelling Lead for the LIGHT Consortium, a cross-disciplinary global health research programme which aims to support policy and practice in transforming gendered pathways to health for people with TB in urban settings, and she chairs the International Union Against Tuberculosis and Lung Disease working group on Gender Equity in TB. 

She has led work within a broader team to quantify the dynamics of pathways across the spectrum of Mtb infection and TB disease. Her current research extends this work to explore the role of early and asymptomatic disease in areas relevant to TB policy and research, including community screening approaches, burden estimation, and trial design. She is a Co-Investigator on PACE TB MOD, which aims to quantify the potential epidemiological and economic impacts of different TB interventions across settings. 

Prior to joining LSHTM, Katherine managed research and surveillance protocols on acute respiratory infections, sexually transmitted infections, and vector-borne and zoonotic infections with the U.S. Centers for Disease Control and Prevention Global Disease Detection Centre in Egypt, and she supported HIV voluntary counselling and testing, cohort studies, and clinical trials with Emory University in Rwanda and Zambia. She has also consulted for the World Health Organization Regional Office for the Western Pacific on pandemic preparedness and rapid response and for the World Health Organization Global TB Programme.