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Julius Hafalla

BSc MSc PhD

Associate Professor
of Immunology and Royal Society University Research Fellow

Room
233

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Tel.
+44 (0)20 7958 8129

Julius Hafalla obtained his BSc in Molecular Biology and Biotechnology (cum laude) from the University of the Philippines – Diliman. He then worked as a Research Assistant at the Research Institute for Tropical Medicine (Philippines) and as a Fogarty Fellow at the International Health Institute of Brown University (USA). Julius obtained his MSc and PhD in Basic Medical Sciences at New York University (USA), where he investigated the development of T cell responses to malaria liver stage infection. He also did post-doctoral work in parasitology, immunology and pre-clinical vaccine development at New York University.

In 2005, Julius joined the LSHTM as a Royal Society Incoming Fellow to study the regulation of pathogenic responses during blood stage malaria infections, and as a Wellcome Trust Visiting Fellow in Public Health and Tropical Medicine to examine cellular immune responses to malaria in Thailand and Tanzania.

In 2008, Julius was awarded a Royal Society University Research Fellowship, which was renewed in 2013. He was appointed as a Senior Lecturer in Immunology in 2013.

Affiliations

Faculty of Infectious and Tropical Diseases
Department of Infection Biology

Centres

Malaria Centre
Vaccine Centre

Teaching

MSc Immunology of Infectious Diseases – core immunology, advanced immunology and parasite immunology

MSc Medical Parasitology – core parasitology

MSc Medical Microbiology – core bacteriology

MSc Molecular Biology of Infectious Diseases – research progress and applications

Research

Julius Hafalla's research investigates factors that govern the magnitude, efficiency and long-term maintenance of protective immune responses to malaria pre-erythrocytic stages. He has an interest in understanding protective and pathological mechanisms involved during malaria blood stage infection. He is involved in infectious disease research in The Philippines.

Research Area
Innate immunity
Parasites
T-cell immunology
Vaccines
Immunisation
Protozoa
Discipline
Genomics
Immunopathology
Cell biology
Genetics
Immunology
Molecular biology
Parasitology
Bioinformatics
Disease and Health Conditions
Infectious disease
Malaria
Dengue
Tropical diseases
Region
East Asia & Pacific (developing only)
Latin America & Caribbean (developing only)
Sub-Saharan Africa (developing only)

Selected Publications

Parasites and tissue microenvironment.
Helmby H; Hafalla JC
2021
Parasite immunology
Low immunogenicity of malaria pre-erythrocytic stages can be overcome by vaccination.
Müller K; Gibbins MP; Roberts M; Reyes-Sandoval A; Hill AVS; Draper SJ; Matuschewski K; Silvie O; Hafalla JCR
2021
EMBO molecular medicine
Enhanced Health Facility Surveys to Support Malaria Control and Elimination across Different Transmission Settings in the Philippines.
Reyes RA; Fornace KM; Macalinao MLM; Boncayao BL; De La Fuente ES; Sabanal HM; Bareng APN; Medado IAP; Mercado ES; Baquilod MS
2021
The American journal of tropical medicine and hygiene
Immune responses to malaria pre-erythrocytic stages: Implications for vaccine development.
Abuga KM; Jones-Warner W; Hafalla JCR
2020
Parasite Immunology
A serological framework to investigate acute primary and post-primary dengue cases reporting across the Philippines.
Biggs JR; Sy AK; Brady OJ; Kucharski AJ; Funk S; Reyes MAJ; Quinones MA; Jones-Warner W; Tu Y-H; Avelino FL
2020
BMC medicine
Disentangling fine-scale effects of environment on malaria detection and infection to design risk-based disease surveillance systems in changing landscapes
Fornace KM; Reyes RA; Macalinao MLM; Bareng APN; Luchavez JS; Hafalla JCR; Espino FEJ; Drakeley CJ
2020
MedRxiv
Importance of the Immunodominant CD8<sup>+</sup> T Cell Epitope of Plasmodium berghei Circumsporozoite Protein in Parasite- and Vaccine-Induced Protection.
Gibbins MP; Müller K; Glover M; Liu J; Putrianti ED; Bauza K; Reyes-Sandoval A; Matuschewski K; Silvie O; Hafalla JCR
2020
Infection and immunity
Comparison of leucocyte profiles between healthy children and those with asymptomatic and symptomatic Plasmodium falciparum infections.
Prah DA; Amoah LE; Gibbins MP; Bediako Y; Cunnington AJ; Awandare GA; Hafalla JCR
2020
Malaria journal
See more Publications