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Julius Hafalla

BSc MSc PhD

Associate Professor
of Immunology and Royal Society University Research Fellow

Room
233

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Tel.
+44 (0)20 7958 8129

Julius Hafalla obtained his BSc in Molecular Biology and Biotechnology (cum laude) from the University of the Philippines – Diliman. He then worked as a Research Assistant at the Research Institute for Tropical Medicine (Philippines) and as a Fogarty Fellow at the International Health Institute of Brown University (USA). Julius obtained his MSc and PhD in Basic Medical Sciences at New York University (USA), where he investigated the development of T cell responses to malaria liver stage infection. He also did post-doctoral work in parasitology, immunology and pre-clinical vaccine development at New York University.

In 2005, Julius joined the LSHTM as a Royal Society Incoming Fellow to study the regulation of pathogenic responses during blood stage malaria infections, and as a Wellcome Trust Visiting Fellow in Public Health and Tropical Medicine to examine cellular immune responses to malaria in Thailand and Tanzania.

In 2008, Julius was awarded a Royal Society University Research Fellowship, which was renewed in 2013. He was appointed as a Senior Lecturer in Immunology in 2013.

Affiliations

Faculty of Infectious and Tropical Diseases
Department of Infection Biology

Centres

Malaria Centre
Vaccine Centre

Teaching

MSc Immunology of Infectious Diseases – core immunology, advanced immunology and parasite immunology

MSc Medical Parasitology – core parasitology

MSc Medical Microbiology – core bacteriology

MSc Molecular Biology of Infectious Diseases – research progress and applications

Research

Julius Hafalla's research investigates factors that govern the magnitude, efficiency and long-term maintenance of protective immune responses to malaria pre-erythrocytic stages. He has an interest in understanding protective and pathological mechanisms involved during malaria blood stage infection. He is involved in infectious disease research in The Philippines.

Research Area
Innate immunity
Parasites
T-cell immunology
Vaccines
Immunisation
Protozoa
Discipline
Genomics
Immunopathology
Cell biology
Genetics
Immunology
Molecular biology
Parasitology
Bioinformatics
Disease and Health Conditions
Infectious disease
Malaria
Dengue
Tropical diseases
Region
East Asia & Pacific (developing only)
Latin America & Caribbean (developing only)
Sub-Saharan Africa (developing only)

Selected Publications

The ecology of immune state in a wild mammal, Mus musculus domesticus.
Abolins S; Lazarou L; Weldon L; Hughes L; King EC; Drescher P; Pocock MJO; Hafalla JCR; Riley EM; Viney M
2018
PLoS biology
Evidence of cross-stage CD8+ T cell epitopes in malaria pre-erythrocytic and blood stage infections.
Müller K; Gibbins MP; Matuschewski K; Hafalla JC
2017
Parasite immunology
Type I Interferon in Malaria: A Balancing Act.
Mooney JP; Wassmer SC; Hafalla JC
2017
Trends in parasitology
The comparative immunology of wild and laboratory mice, Mus musculus domesticus.
Abolins S; King EC; Lazarou L; Weldon L; Hughes L; Drescher P; Raynes JG; Hafalla JCR; Viney ME; Riley EM
2017
Nature communications
Host Resistance to Plasmodium-Induced Acute Immune Pathology Is Regulated by Interleukin-10 Receptor Signaling.
Claser C; De Souza JB; Thorburn SG; Grau GE; Riley EM; Rénia L; Hafalla JCR
2017
Infection and immunity
Tissue-specific cellular immune responses to malaria pre-erythrocytic stages.
Silvie O; Amino R; Hafalla JC
2017
Current opinion in microbiology
An in vitro assay to measure antibody-mediated inhibition of P. berghei sporozoite invasion against P. falciparum antigens.
Rodríguez-Galán A; Salman AM; Bowyer G; Collins KA; Longley RJ; Brod F; Ulaszewska M; Ewer KJ; Janse CJ; Khan SM
2017
Scientific reports
Signatures of malaria vaccine efficacy in ageing murine immune memory
Haussig JM; Burgold J; Hafalla JCR; Matuschewski K; Kooij TWA
2014
Parasite immunology
See more Publications