of Vaccine Epidemiology & co-director of CMMID
Since my PhD years I have been fascinated by the complexities and challenges of pneumococcal vaccination which has been one of my my main foci of work. My research in this area is currently supported through a Sir Henry Dale Wellcome Trust Fellowship alongside other research grants.
I have also been frequently following related interest, e.g. outbreak response (SARS-CoV-2, ebola and swine flu), antimicrobial resistance, vector bourne disease (dengue and malaria) and health in humanitarian crises.
I currently am co-director of CMMID, a member of WHO's IVIR-AC, co-chair of WHO SAGE'S COVID19 vaccine modelling subgroup and serve on a WHO SAGE's working groups on pneumococcal conjugate vaccines, on dengue vaccines and on COVID19 vaccines. I also serve on the Joint Committee on Vaccination and Immunisation's (JCVI) pneumococcal subgroup.
I teach on the modelling short course and the MSc module, on STEPH and ECCD and I co-organise and teach on the short course on epidemiological evaluation of vaccines. I supervise two to three Master student summer projects each year and a number of PhD projects (I am currently unable to take on any more PhD students).
My main research area is the evaluation and optimisation of vaccine interventions. For S. pneumoniae this includes using mathematical models to help better understand how to use existing pneumococcal vaccine more efficiently, ie reducing cost and maximising impact, and to help designing optimal future vaccine formulations.
My team and I work closely with a range of international partners including on vaccine trials and their interpretation in Vietnam and in humanitarian crises settings.
My other interests include real-time evaluation of pandemic pathogens as well as evolution and mitigation of AMR, assessing and predicting the impact of vaccines against seasonal influenza, HiB, varicella zoster, melioidosis, non-typhoid salmonella, RSV, hand foot and mouth disease, malaria and dengue.