Prof Diana Elbourne

Professor of Health Care Evaluation

United Kingdom

My first degree was in Social Administration from London School of Economics (LSE), after which I gained an MSc (Stats) at Brunel University, where I also worked as a statistics lecturer. My PhD at LSE was based on a randomised controlled trial (RCT) of women having access to their maternity care records. From 1981-1996 I was at the National Perinatal Epidemiology Unit in Oxford, holding the roles of social statistician, trials statistician, Deputy Director and and later Director of the Perinatal Trials Service. During this period I was involved in a large number of RCTs and systematic reviews. I continued this applied research after moving to LSHTM in 1997, broadening from the perinatal field to also include trials in liver transplantation, intensive care, heart disease, children with diabetes, adolescents, and educational and nutritional interventions. Between 2000 and 2005 I worked half-time as professor of Evidence-informed policy and practice in the Evidence for Policy and Practice Information and Coordination Centre in the Institute of Education. I currently work part time in the Medical Statistics Dept. (MSD).


Department of Medical Statistics
Faculty of Epidemiology and Population Health


Malaria Centre
Centre for Maternal Adolescent Reproductive & Child Health


My main teaching interests are in clinical trials especially the MSc in clinical trials by distance learning where i am co-director.


My main interest as a statistician is in randomised controlled trials (RCTs). As a triallist I work with a highly experienced team in the MSD and the LSHTM CTU to design, co-ordinate, analyse and report a number of RCTs. Currently these trials include perinatal and child health trials in Uganda and India, cardiac care in the UK, and school-based trials in India.

My methodological research includes data monitoring committees, reporting of trials (especially cluster, non-inferiority, within-person, cross-over and factorial RCTs), research reactivity, and qualitative research on the views of people participating in trials.

Selected Publications

Effectiveness of kangaroo mother care before clinical stabilisation versus standard care among neonates at five hospitals in Uganda (OMWaNA): a parallel-group, individually randomised controlled trial and economic evaluation.
Tumukunde, V; Medvedev, MM; TANN, CJ; Mambule, I; PITT, C; OPONDO, C; Kakande, A; Canter, R; Haroon, Y; Kirabo-Nagemi, C; ABAASA, A; Okot, W; Katongole, F; Ssenyonga, R; Niombi, N; NANYUNJA, C; ELBOURNE, D; GRECO, G; Ekirapa-Kiracho, E; NYIRENDA, M; ALLEN, E; Waiswa, P; LAWN, JE; OMWaNA Collaborative Authorship Group,;
Statistical analysis plan for a cluster randomised trial in Madhya Pradesh, India: community health promotion and medical provision and impact on neonates (CHAMPION2).
MAGILL, N; SHIVALLI, S; Fazzio, I; ELBOURNE, D; Keddie, S; Reddy, P; Nair, R; Gopal, M; Karnati, S; Reddy, H; Boone, P; FROST, C;
Assessing efficacy in non-inferiority trials with non-adherence to interventions: Are intention-to-treat and per-protocol analyses fit for purpose?
Statistics in medicine
Upscaling Participatory Action and Videos for Agriculture and Nutrition (UPAVAN) study data
FIVIAN, E; HARRIS-FRY, H; Pradhan, R; Mohanty, S; Padhan, S; Rath, S; James, P; Koniz-Booher, P; Nair, N; Haghparast-Bidgoli, H; Kishor Mishra, N; Rath, S; BEAUMONT, E; Danton, H; Krishnan, S; Parida, M; Kumar, A; Upadhyay, A; Tripathy, P; Skordis, J; STURGESS, J; ELBOURNE, D; Prost, A; ALLEN, E; KADIYALA, S;
London School of Hygiene & Tropical Medicine
The Learning Together intervention: study data from three surveys in the INCLUSIVE cluster randomised controlled trial
BONELL, C; ALLEN, E; WARREN, E; McGowan, J; Bevilacqua, L; Jamal, F; Legood, R; Wiggins, M; OPONDO, C; Mathiot, A; STURGESS, J; Fletcher, A; SADIQUE, Z; ELBOURNE, D; Christie, D; Bond, L; Scott, S; Viner, R;
London School of Hygiene & Tropical Medicine
Reporting of Factorial Randomized Trials: Extension of the CONSORT 2010 Statement.
Kahan, BC; Hall, SS; Beller, EM; Birchenall, M; Chan, A-W; ELBOURNE, D; Little, P; Fletcher, J; Golub, RM; Goulao, B; Hopewell, S; Islam, N; Zwarenstein, M; Juszczak, E; Montgomery, AA;
Consensus Statement for Protocols of Factorial Randomized Trials: Extension of the SPIRIT 2013 Statement.
Kahan, BC; Hall, SS; Beller, EM; Birchenall, M; ELBOURNE, D; Juszczak, E; Little, P; Fletcher, J; Golub, RM; Goulao, B; Hopewell, S; Islam, N; Zwarenstein, M; Chan, A-W; Montgomery, AA;
JAMA network open
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