Professor Diana Elbourne


of Healthcare Evaluation


Keppel Street
United Kingdom

020 7927 2629

My first degree was in Social Administration from London School of Economics (LSE), after which I gained an MSc (Stats) at Brunel University, where I also worked as a statistics lecturer. My PhD at LSE was based on a randomised controlled trial (RCT) of women having access to their maternity care records. From 1981-1996 I was at the National Perinatal Epidemiology Unit in Oxford, holding the roles of social statistician, trials statistician, Deputy Director and and later Director of the Perinatal Trials Service.

During this period I was involved in a large number of RCTs and systematic reviews. I continued this applied research after moving to LSHTM in 1997, broadening from the perinatal field to also include trials in liver transplantation, intensive care, heart disease, children with diabetes, adolescents, and educational and nutritional interventions.  Between 2000 and 2005 I worked half-time as professor of Evidence-informed policy and practice in the Evidence for Policy and Practice Information and Coordination Centre in the Institute of Education.


Department of Medical Statistics
Faculty of Epidemiology and Population Health


Centre for Evaluation
Centre for Maternal Adolescent Reproductive & Child Health (MARCH)
Centre for Statistical Methodology
Centre on Climate Change and Planetary Health


My main teaching interests are in clinical trials especially the MSc in clinical trials by distance learning where i am co-director.


My main interest as a statistician is in randomised controlled trials (RCTs). As a triallist I work with a highly experienced team in the MSD and the LSHTM CTU to design, co-ordinate, analyse and report a number of RCTs. Currently these trials include perinatal and child health trials in the Gambia, Uganda and India, cardiac care in the UK, and school-based trials in the UK, Gambia and India.

My methodological research includes data monitoring committees, reporting of trials (especially cluster, non-inferiority, within-person, cross-over and factorial RCTs),  research reactivity, and qualitative research on the views of people participating in trials.

Research Area
Child health
Clinical trials
Complex interventions
Health promotion
Health services research
Health technology assessment
Maternal health
Perinatal health
Sexual health
Systematic reviews
Critical care
Impact evaluation
Mixed methods
Neonatal health
Implementation research
Qualitative methods
Randomised controlled trials
Reproductive health
Social Sciences
Disease and Health Conditions
Cardiovascular disease
Chronic Fatigue Syndrome
United Kingdom
The Gambia
Europe & Central Asia (all income levels)
European Union
Least developed countries: UN classification
Sub-Saharan Africa (developing only)

Selected Publications

Maintenance of Serum Potassium Levels ≥3.6 mEq/L Versus ≥4.5 mEq/L After Isolated Elective Coronary Artery Bypass Grafting and the Incidence of New-Onset Atrial Fibrillation: Pilot and Feasibility Study Results.
Campbell NG; Allen E; Montgomery H; Aron J; Canter RR; Dodd M; Sanders J; Sturgess J; Elbourne D; O'Brien B
Journal of cardiothoracic and vascular anesthesia
Statistical methods for non-adherence in non-inferiority trials: useful and used? A systematic review.
Dodd M; Fielding K; Carpenter JR; Thompson JA; Elbourne D
BMJ open
Reducing bias in trials from reactions to measurement: the MERIT study including developmental work and expert workshop
French DP; Miles LM; Elbourne D; Farmer A; Gulliford M; Locock L; Sutton S; McCambridge J
Health technology assessment (Winchester, England)
Reducing bias in trials due to reactions to measurement: experts produced recommendations informed by evidence.
French DP; Miles LM; Elbourne D; Farmer A; Gulliford M; Locock L; Sutton S; McCambridge J; MERIT Collaborative Group
Journal of Clinical Epidemiology
Patient and public involvement prior to trial initiation: lessons learnt for rapid partnership in the COVID-19 era.
Jamal Z; Perkins A; Allen C; Research Advisory Group; Evans R; Sturgess J; Snowdon C; Clayton T; Elbourne D
Research involvement and engagement
A school-based social-marketing intervention to promote sexual health in English secondary schools: the Positive Choices pilot cluster RCT
Ponsford R; Bragg S; Allen E; Tilouche N; Meiksin R; Emmerson L; Van Dyck L; Opondo C; Morris S; Sturgess J
Public Health Research
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