Prof Diana Elbourne

Professor of Health Care Evaluation

United Kingdom

My first degree was in Social Administration from London School of Economics (LSE), after which I gained an MSc (Stats) at Brunel University, where I also worked as a statistics lecturer. My PhD at LSE was based on a randomised controlled trial (RCT) of women having access to their maternity care records. From 1981-1996 I was at the National Perinatal Epidemiology Unit in Oxford, holding the roles of social statistician, trials statistician, Deputy Director and and later Director of the Perinatal Trials Service. During this period I was involved in a large number of RCTs and systematic reviews. I continued this applied research after moving to LSHTM in 1997, broadening from the perinatal field to also include trials in liver transplantation, intensive care, heart disease, children with diabetes, adolescents, and educational and nutritional interventions. Between 2000 and 2005 I worked half-time as professor of Evidence-informed policy and practice in the Evidence for Policy and Practice Information and Coordination Centre in the Institute of Education. I currently work part time in the Medical Statistics Dept. (MSD).


Department of Medical Statistics
Faculty of Epidemiology and Population Health


Centre for Evaluation
Malaria Centre
Centre for Maternal Adolescent Reproductive & Child Health


My main teaching interests are in clinical trials especially the MSc in clinical trials by distance learning where i am co-director.


My main interest as a statistician is in randomised controlled trials (RCTs). As a triallist I work with a highly experienced team in the MSD and the LSHTM CTU to design, co-ordinate, analyse and report a number of RCTs. Currently these trials include perinatal and child health trials in Uganda and India, cardiac care in the UK, and school-based trials in India.

My methodological research includes data monitoring committees, reporting of trials (especially cluster, non-inferiority, within-person, cross-over and factorial RCTs), research reactivity, and qualitative research on the views of people participating in trials.

Selected Publications

Reporting of Factorial Randomized Trials: Extension of the CONSORT 2010 Statement.
Kahan, BC; Hall, SS; Beller, EM; Birchenall, M; Chan, A-W; ELBOURNE, D; Little, P; Fletcher, J; Golub, RM; Goulao, B; Hopewell, S; Islam, N; Zwarenstein, M; Juszczak, E; Montgomery, AA;
Consensus Statement for Protocols of Factorial Randomized Trials: Extension of the SPIRIT 2013 Statement.
Kahan, BC; Hall, SS; Beller, EM; Birchenall, M; ELBOURNE, D; Juszczak, E; Little, P; Fletcher, J; Golub, RM; Goulao, B; Hopewell, S; Islam, N; Zwarenstein, M; Chan, A-W; Montgomery, AA;
JAMA network open
Statistical analysis plan for a cluster randomised trial in Madhya Pradesh, India: support to rural India's public education system and impact on numeracy and literacy scores (STRIPES2).
KEDDIE, S; Fazzio, I; SHIVALLI, S; MAGILL, N; ELBOURNE, D; Sharma, D; Shekhawat, SS; Banerji, R; Karnati, S; Reddy, H; Eble, A; Boone, P; FROST, C;
Process and costs for readiness to safely implement immediate kangaroo mother care: a mixed methods evaluation from the OMWaNA trial at five hospitals in Uganda.
MEDVEDEV, MM; Tumukunde, V; Kirabo-Nagemi, C; GRECO, G; Mambule, I; KATUMBA, K; Waiswa, P; TANN, CJ; ELBOURNE, D; ALLEN, E; Ekirapa-Kiracho, E; PITT, C; LAWN, JE;
BMC health services research
WILL (When to Induce Labour to Limit risk in pregnancy hypertension): a multicentre randomised controlled trial - adaptations to deliver a timing-of-birth trial during the COVID-19 international pandemic.
Magee, LA; Tohill, S; Kirkham, K; Evans, R; Gkini, E; Moakes, CA; Stubbs, C; Thornton, J; Von Dadelszen, P; WILL Trial Study Group,;
Prof. Diana R. Elbourne: CONSORT for Cluster Randomized Trials and CONSORT for Noninferiority and Equivalence Trials.
Du, KJ; Li, GS; Zhang, K; Lin, Y; Yang, F; ELBOURNE, DR;
Annals of translational medicine
Understanding the effects of nutrition-sensitive agriculture interventions with participatory videos and women's group meetings on maternal and child nutrition in rural Odisha, India: A mixed-methods process evaluation.
Prost, A; HARRIS-FRY, H; Mohanty, S; Parida, M; Krishnan, S; FIVIAN, E; Rath, S; Nair, N; Mishra, NK; Padhan, S; Pradhan, R; Sahu, S; Skordis, J; Danton, H; Koniz-Booher, P; BEAUMONT, E; James, P; ALLEN, E; ELBOURNE, D; KADIYALA, S;
Maternal and Child Nutrition
Maintenance of Serum Potassium Levels ≥3.6 mEq/L Versus ≥4.5 mEq/L After Isolated Elective Coronary Artery Bypass Grafting and the Incidence of New-Onset Atrial Fibrillation: Pilot and Feasibility Study Results.
Campbell, NG; ALLEN, E; Montgomery, H; Aron, J; CANTER, RR; DODD, M; Sanders, J; STURGESS, J; ELBOURNE, D; O'Brien, B;
Journal of Cardiothoracic and Vascular Anesthesia
Statistical methods for non-adherence in non-inferiority trials: useful and used? A systematic review.
BMJ open
Feasibility and acceptability of a whole-school social-marketing intervention to prevent unintended teenage pregnancies and promote sexual health: evidence for progression from a pilot to a phase III randomised trial in English secondary schools.
PONSFORD, R; Bragg, S; MEIKSIN, R; TILOUCHE, N; Van Dyck, L; STURGESS, J; ALLEN, E; ELBOURNE, D; Hadley, A; Lohan, M; Mercer, CH; Melendez Torres, GJ; Morris, S; Young, H; Campbell, R; BONELL, C;
Pilot and feasibility studies
See more information