Close

Prof Chris Drakeley

Professor of Infection and Immunity

United Kingdom

Tel.
+442079272289
I have 30 years’ experience working on malaria with a specific focus on measuring and defining transmission and identifying methods and approaches to stop it. My research includes (i) exploratory work on factors governing transmission and transmission reservoirs, particularly the importance of adults, asymptomatic parasite carriers and people with very low parasitaemias; and (ii) assessing the impact of drugs on transmission and optimal control approaches for transmission reduction. I have led two large programmes funded by BMGF; firstly elucidating the infectious reservoir of transmission in different endemic settings in Kenya and Burkina Faso senior investigator and secondly evaluating the effect of control measures on the infectious reservoir in Uganda, The Gambia, Ethiopia and Burkina Faso. I have also been a senior investigator on large community randomized control studies evaluating school based interventions, foci targeting and mass drug administration. This has included developed operational and laboratory approaches to best evaluate efficacy. My current activities leading several initiatives aimed at further describing transmission and using surveillance to more effectively assess intervention success. OTher focus areas include better understanding of the transmission of zoonotic malaria P.knowlesi and the development of serological assays for malaria (particularly P.vivax) and other infectious diseases.

Affiliations

Department of Infection Biology
Faculty of Infectious and Tropical Diseases

Centres

Malaria Centre
Vaccine Centre
Centre on Climate Change and Planetary Health

Research

Malaria - Epidemiology, surveillance and transmission
Diagnostics - serological assays
Research Area
Surveillance
Diagnostics
Disease control
Epidemiology
Immunoepidemiology
Immunology
Disease and Health Conditions
Malaria
Neglected Tropical Diseases (NTDs)
Country
Gambia
Uganda
Burkina Faso
Philippines
Ethiopia
Madagascar
Region
Sub-Saharan Africa (developing only)
Latin America & Caribbean (developing only)
East Asia & Pacific (developing only)

Selected Publications

Extension of efficacy range for targeted malaria-elimination interventions due to spillover effects.
Benjamin-Chung, J; Li, H; Nguyen, A; Barratt Heitmann, G; Bennett, A; Ntuku, H; Prach, LM; Tambo, M; Wu, L; DRAKELEY, C; GOSLING, R; Mumbengegwi, D; KLEINSCHMIDT, I; Smith, JL; Hubbard, A; Van der Laan, M; Hsiang, MS;
2024
Nature medicine
Plasmodium falciparum gametocyte production correlates with genetic markers of parasite replication but is not influenced by experimental exposure to mosquito biting
Blanken, SL; Barry, A; Lanke, K; Guelbeogo, M; Ouedraogo, A; Soulama, I; Coulibaly, SA; Teelen, K; Graumans, W; Dumont, E; STONE, W; Ramjith, J; Marti, M; Andrade, CM; DRAKELEY, C; Collins, K; Tiono, A; Bousema, T;
2024
eBioMedicine
Artemether–lumefantrine with or without single-dose primaquine and sulfadoxine–pyrimethamine plus amodiaquine with or without single-dose tafenoquine to reduce Plasmodium falciparum transmission: a phase 2, single-blind, randomised clinical trial in Ouelessebougou, Mali
Mahamar, A; Smit, MJ; Sanogo, K; Sinaba, Y; Niambele, SM; Sacko, A; Dicko, OM; Diallo, M; Maguiraga, SO; Sankaré, Y; Keita, S; Samake, S; Dembele, A; Lanke, K; Ter Heine, R; BRADLEY, J; Dicko, Y; Traore, SF; DRAKELEY, C; Dicko, A; Bousema, T; STONE, W;
2024
The Lancet Microbe
Household-level effects of seasonal malaria chemoprevention in the Gambia.
SOREMEKUN, S; Conteh, B; Nyassi, A; Soumare, HM; Etoketim, B; Ndiath, MO; BRADLEY, J; D'Alessandro, U; Bousema, T; Erhart, A; Moreno, M; DRAKELEY, C;
2024
Communications medicine
Landscape drives zoonotic malaria prevalence in non-human primates
Johnson, E; Sunil Kumar Sharma, R; Ruiz Cuenca, P; BYRNE, I; Salgado-Lynn, M; Suraya Shahar, Z; Col Lin, L; Zulkifli, N; Dilaila Mohd Saidi, N; DRAKELEY, C; Matthiopoulos, J; Nelli, L; Fornace, K;
2024
eLife
Landscape drives zoonotic malaria prevalence in non-human primates.
Johnson, E; Sunil Kumar Sharma, R; Ruiz Cuenca, P; BYRNE, I; Salgado-Lynn, M; Suraya Shahar, Z; Col Lin, L; Zulkifli, N; Dilaila Mohd Saidi, N; DRAKELEY, C; Matthiopoulos, J; Nelli, L; Fornace, K;
2024
eLife
ManuelaQuaresma/CSI
Rubio, FJ; Quaresma, M; RACHET, B;
2024
Github
The impact of weekly fever-screening and treatment and monthly RDT testing and treatment on the infectious reservoir of malaria in Burkina Faso: results from a cluster-randomised trial
Bousema, T; Collins, K; Ouedraogo, A; Guelbeogo, WM; Soulama, I; Ouattara, M; Sobie, S; Ouedraogo, N; Coulibaly, A; Nombre, A; Lanke, K; Ramjith, J; Awandu, S; Serme, S; Henry, N; STONE, WJ R; Ouedraogo, I; Holden, T; Sirima, S; BRADLEY, J; Soremekun, S; Selvaraj, P; Gerardin, J; DRAKELEY, C; Tiono, A;
2024
Dryad
The effect of RTS,S/AS01E and SMC alone or combined on the acquisition of blood stage antimalarial antibody responses
PATTERSON, C; SOREMEKUN, S; Dicko, A; Ouedraogo, J-B; Zongo, I; Sagara, I; Snell, P; Lee, C; Ockenhouse, C; Ofori-Anyinam, O; Tinto, H; Chandramohan, D; GREENWOOD, B; DRAKELEY, C;
2024
The effect of RTS,S/AS01E and SMC alone or combined on the acquisition of blood stage antimalarial antibody responses
PATTERSON, K; SOREMEKUN, S; DRAKELEY, C; GREENWOOD, B; Chandramohan, D; Snell, P; Dicko, A; Ouedraogo, J-B; Tinto, H; Zongo, I; Sagara, I; Ofori-Anyinam, O; Lee, C; Ookenhouse, C;
2024
See more information