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Mr Matthew Dodd

Assistant Professor

United Kingdom

I have worked at the London School of Hygiene and Tropical Medicine (LSHTM) since February 2013. Initially, I worked as a Data Manager within the Clinical Trials Unit (CTU), before completing an MSc in Medical Statistics at LSHTM and starting a new role as a Research Fellow in Medical Statistics. This role involves providing data management and statistical support for several randomised controlled trials overseen by the LSHTM CTU. In March 2025, I completed a part-time PhD assessing the performance of statistical methods for handling non-adherence to interventions in randomised non-inferiority trials.

Affiliations

Department of Medical Statistics
Faculty of Epidemiology and Population Health

Teaching

I am co-module organiser for the face-to-face Clinical Trials module (2033) and teach predominantly on this course. I also tutor on the Regression module for the MSc in Medical Statistics and assist with the distance learning module Basic Statistics for Clinical Trials (CTM102).

Research

I am currently providing statistical support for the following randomised controlled trials:

AIMS (investigating the effect of Irbesartan on aortic dilatation in Marfan syndrome)
ARREST (investigating the effect of expedited transfer to a cardiac arrest centre for non-ST elevation out-of-hospital cardiac arrest; arrest.lshtm.ac.uk)
BHF PROTECT-TAVI (investigating the effect of a cerebral embolic protection device in participants with aortic valve stenosis planned for treatment by transcatheter aortic valve implantation)
CHIP-BCIS3 (investigating the effect of a strategy of percutaneous left ventricular unloading in patients undergoing high-risk percutaneous coronary intervention (PCI))
ERIC-PPCI (investigating the effect of remote ischaemic conditioning on clinical outcomes in ST-segment elevation myocardial infarction patients undergoing primary PCI; ericppci.lshtm.ac.uk)
PREVENTT (investigating the effect of intravenous iron in patients with anaemia undergoing major open abdominal surgery; preventt.lshtm.ac.uk)
REVIVED-BCIS2 (investigating the effect of PCI compared to optimal medical therapy alone for ischaemic left ventricular dysfunction; revived.lshtm.ac.uk)
TB Practecal (evaluating regimens containing Bedaquiline and Pretomanid for the treatment of adult patients with pulmonary multidrug resistant tuberculosis; msf.org.uk/tb-practecal)

Selected Publications

Surgical Risk and Revascularization—An Update
Marquis-Gravel, G; Tong, G; DODD, M; CLAYTON, T; Ryan, M; Docherty, KF; Williams, A; Sun, J; Fremes, SE; Lansky, AJ; Velazquez, EJ; Perera, D; Petrie, MC; Rouleau, J-L;
2026
Journal of the Society for Cardiovascular Angiography & Interventions
Left Ventricular Unloading in High-Risk Percutaneous Coronary Intervention.
Perera, D; Ryan, M; Ezad, SM; Khan, SQ; Webb, I; O'Kane, PD; Weerackody, R; DODD, M; KWOK, M; Laidlaw, L; Van Dyck, L; Wrigley, B; Strange, JW; Bagnall, A; Fath-Ordoubadi, F; Panoulas, VF; Ladwiniec, A; Davies, JR; Chase, A; Owens, CG; Watkins, S; Rahman, H; Pareek, N; Rathod, K; Rawlins, J; ... CHIP-BCIS3 Investigators,
2026
The New England journal of medicine
Expedited transfer to emergency department vs. cardiac catheter laboratory in a cardiac arrest centre for non-ST-elevation out-of-hospital cardiac arrest: ARREST trial as-treated analysis.
Patterson, T; Perkins, GD; DODD, M; PERKINS, A; Mellett-Smith, A; Fothergill, RT; CLAYTON, T; Evans, R; ROBERTSON, S; KWOK, M; Wilson, K; McDonaugh, B; McCrone, P; Dalby, M; Firoozi, S; Malik, I; Rakhit, R; Jain, A; MacCarthy, P; Nolan, JP; Redwood, SR; ARREST Trial Collaborators,;
2025
European heart journal. Acute cardiovascular care
Cerebral Embolic Protection during TAVI. Reply.
Kharbanda, RK; Kennedy, J; DODD, M;
2025
The New England journal of medicine
Impact of baseline risk of death or hospitalization on effectiveness of revascularization in patients with ischaemic left ventricular dysfunction-a prespecified analysis of REVIVED-BCIS2.
Ovesen, C; DODD, M; Ryan, M; CLAYTON, T; SHARPLES, L; Perera, D;
2025
European heart journal. Quality of care & clinical outcomes
Accommodating Asymmetric Adherence in Clinical Trial Analyses: Insights From BHF PROTECT-TAVI
Kennedy, J; DODD, M; Read, L; JAMAL, Z; Bal, KK; Stables, RH; Henderson, R; Evans, R; CLAYTON, T; Kharbanda, RK; BHF PROTECT-TAVI Investigators,;
2025
Journal of the American College of Cardiology
Impact of Cerebral Embolic Protection on Cognitive Function After Transcatheter Aortic Valve Implantation: Data From the BHF PROTECT-TAVI Randomized Trial.
Kennedy, J; Blackman, DJ; DODD, M; Poggesi, A; Read, L; JAMAL, Z; Evans, R; CLAYTON, T; Kharbanda, RK; Hildick-Smith, D; BHF PROTECT-TAVI Investigators,;
2025
Circulation
Surgical Risk and Long-Term Mortality With PCI and CABG in Ischemic Left Ventricular Systolic Dysfunction.
Marquis-Gravel, G; Tong, G; DODD, M; CLAYTON, T; Ryan, M; Docherty, KF; Williams, A; Sun, J; Fremes, SE; Lansky, AJ; Velazquez, EJ; Perera, D; Petrie, MC; Rouleau, J-L;
2025
Journal of the Society for Cardiovascular Angiography & Interventions
Myocardial Scar and Arrhythmic Risk Stratification in Ischemic Left Ventricular Systolic Dysfunction.
Morgan, H; Chiribiri, A; Nazir, MS; Zaidi, H; Mancio, J; Alskaf, E; DODD, M; Bishop, M; Rinaldi, CA; Perera, D;
2025
JACC. Cardiovascular imaging
Efficient statistical analysis of trial designs: win ratio and related approaches for composite outcomes
Fandino, W; DODD, M; Kunst, G; Clayton, T;
2025
Perioperative medicine (London, England)
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