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Professor Hazel Dockrell

BA PhD

Professor
of Immunology, Special Advisor on Overseas Partnerships in Africa

Room
396

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Tel.
020 7927 2466

I joined the LSHTM in 1985, following a BA degree in Microbiology at Trinity College Dublin, a PhD in autoimmunity at the Royal Dental Hospital of London post-doctoral reseaech at the Middlesex Hospital Medical School working on the immunology of malari. At LSHTM , I initially worked on the immunology of leprosy but then on tuberculosis, BCG vaccination and biomarkers.

Affiliations

Faculty of Infectious and Tropical Diseases
Executive Office
Department of Infection Biology

Centres

TB Centre
Vaccine Centre

Teaching

 I teach and tutor on the MSc Immunology of Infectious Diseases course.

Research

Our research aims to understand the basis of protective immunity against tuberculosis and in particular to identify biomarker signatures that would help in the development of new TB vaccines. We are also interested in how TB treatment modulates immune and gene expression signatures, and in how co-morbidity with helminth infections or diabetes impact on immunity to Mycobacterium tuberculosis. More recently we have also been working on immune responses in people with chronic fatigue syndrome (ME/CFS).

Research Area
Helminths
T-cell immunology
Vaccines
Capacity strengthening
Global Health
Immunisation
Discipline
Immunoepidemiology
Immunology
Vaccinology
Disease and Health Conditions
Infectious disease
Leprosy
Tuberculosis
Chronic Fatigue Syndrome
Diabetes
Country
Ethiopia
United Kingdom
The Gambia
Republic of Korea
Pakistan
Uganda
South Africa
Region
East Asia & Pacific (all income levels)
European Union
Sub-Saharan Africa (all income levels)

Selected Publications

A next generation BCG vaccine moves forward.
Dockrell HM
2022
The Lancet. Infectious diseases
Impaired resolution of blood transcriptomes through tuberculosis treatment with diabetes comorbidity
Eckold C; van Doorn CLR; Ruslami R; Ronacher K; Riza A-L; van Veen S; Lee J-S; Kumar V; Kerry-Barnard S; Malherbe ST
2022
Cold Spring Harbor Laboratory
Concurrent evaluation of cytokines improves the accuracy of antibodies against Mycobacterium tuberculosis antigens in the diagnosis of active tuberculosis.
Jacobs R; Awoniyi DO; Baumann R; Stanley K; McAnda S; Kaempfer S; Malherbe ST; Singh M; Walzl G; Chegou NN
2022
Tuberculosis (Edinburgh, Scotland)
Regulatory T cells in erythema nodosum leprosum maintain anti-inflammatory function.
Negera E; Bobosha K; Aseffa A; Dockrell HM; Lockwood DNJ; Walker SL
2022
PLoS Neglected Tropical Diseases
Transcriptional profiles predict treatment outcome in patients with tuberculosis and diabetes at diagnosis and at two weeks after initiation of anti-tuberculosis treatment
van Doorn CLR; Eckold C; Ronacher K; Ruslami R; van Veen S; Lee J-S; Kumar V; Kerry-Barnard S; Malherbe ST; Kleynhans L
2022
Cold Spring Harbor Laboratory
Transcriptional profiles predict treatment outcome in patients with tuberculosis and diabetes at diagnosis and at two weeks after initiation of anti-tuberculosis treatment.
van Doorn CLR; Eckold C; Ronacher K; Ruslami R; van Veen S; Lee J-S; Kumar V; Kerry-Barnard S; Malherbe ST; Kleynhans L
2022
EBioMedicine
See more Publications