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Professor Hazel Dockrell

BA PhD

Professor
of Immunology, Special Advisor on Overseas Partnerships in Africa

Room
286

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Tel.
020 7927 2466

I initially did a BA degree in Microbiology at Trinity College Dublin, followed by a PhD in autoimmunity at the Royal Dental Hospital of London. After a period as a postdoc at the Middlesex Hospital Medical School working on malaria, I moved to the LSHTM in 1985. Initially I was working on the immunology of leprosy but this then led me into tuberculosis, BCG vaccination and biomarkers. I now also help as Special Advisor on our Overseas Programmes in Africa.

Affiliations

Department of Infection Biology
Faculty of Infectious and Tropical Diseases
Executive Office

Centres

Tuberculosis (TB) Centre
Vaccine Centre

Teaching

With members of my research group, I teach and tutor on the MSc Immunology of Infectious Diseases course.

Research

Our research aims to understand the basis of protective immunity against tuberculosis and in particular to identify biomarker signatures that would help in the development of new TB vaccines. We are also interested in how TB treatment modulates immune and gene expression signatures, and in how co-morbidity with helminth infections or diabetes impact on immunity to Mycobacterium tuberculosis.

Research Area
Helminths
T-cell immunology
Vaccines
Capacity strengthening
Global Health
Immunisation
Discipline
Immunoepidemiology
Immunology
Vaccinology
Disease and Health Conditions
Infectious disease
Leprosy
Tuberculosis
Chronic Fatigue Syndrome
Diabetes
Country
Ethiopia
United Kingdom
Indonesia
Korea, Rep.
Pakistan
Romania
Uganda
South Africa
Region
East Asia & Pacific (all income levels)
European Union
Sub-Saharan Africa (all income levels)

Selected Publications

Cellular Immune Function in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS).
Cliff JM; King EC; Lee J-S; SepĂșlveda N; Wolf A-S; Kingdon C; Bowman E; Dockrell HM; Nacul L; Lacerda E
2019
Frontiers in Immunology
In vitro Mycobacterial Growth Inhibition in South Korean Adults With Latent TB Infection.
Lee H; Kim J; Kang YA; Kim DR; Sim B; Zelmer A; Fletcher HA; Dockrell HM; Smith SG; Cho S-N
2019
Frontiers in Immunology
Circulating levels of GDF15 in patients with myalgic encephalomyelitis/chronic fatigue syndrome.
Melvin A; Lacerda E; Dockrell HM; O'Rahilly S; Nacul L
2019
Journal of translational medicine
Evidence of Clinical Pathology Abnormalities in People with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) from an Analytic Cross-Sectional Study.
Nacul L; de Barros B; Kingdon CC; Cliff JM; Clark TG; Mudie K; Dockrell HM; Lacerda EM
2019
Diagnostics (Basel, Switzerland)
Distinct serum biosignatures are associated with different tuberculosis treatment outcomes.
Ronacher K; Chegou NN; Kleynhans L; Djoba Siawaya JF; du Plessis N; Loxton AG; Maasdorp E; Tromp G; Kidd M; Stanley K
2019
Tuberculosis
Diabetes is associated with genotypically drug-resistant tuberculosis.
Ruesen C; Chaidir L; Ugarte-Gil C; van Ingen J; Critchley JA; Hill PC; Ruslami R; Santoso P; Huynen MA; Dockrell HM
2019
The European respiratory journal
Mitochondrial function signature in fumarate-induced monocyte innate immune training
Sanchez-Garcia FJ; Smith S; Butkeviciute E; McCarthy E; Perez-Hernandez A; Aguilar-Lopez BA; Lopez-Villegas EO; Kern CC; Bhosale G; Duchen MR
2019
EUROPEAN JOURNAL OF IMMUNOLOGY
Diabetes Mellitus Among Pulmonary Tuberculosis Patients From 4 Tuberculosis-endemic Countries: The TANDEM Study.
Ugarte-Gil C; Alisjahbana B; Ronacher K; Riza AL; Koesoemadinata RC; Malherbe ST; Cioboata R; Llontop JC; Kleynhans L; Lopez S
2019
Clinical infectious diseases
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