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Mr John Dallow

Scientific Officer
Mycobacteriology

Room
490

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

I have been working on the development and surveillance of anti-infectives in industry for over 15 years.  I started my career in post-marketing, resistance surveillance of respiratory pathogens across the globe, studying the epidemiological and usage considerations of new and established anti-infectives.  More recently, my focus has moved to early drug discovery, helping characterise novel antimicrobial agents and identify targets using genetic engineering and interference in whole cell assays.  In recent months, my work has also focussed on combating Covid-19 by disrupting interactions reported between the SARS-CoV-2 virus and human cells.

Affiliations

Faculty of Infectious and Tropical Diseases
Department of Infection Biology

Centres

TB Centre
Antimicrobial Resistance Centre (AMR)

Research

My research has focused on harnessing bacterial genetics to identify targets of antimicrobial compounds and to assess drug pharmacology from a microbiological perspective.  I have worked on assessing how different PK/PD parameters work in in vitro models to drive bacterial kill, optimising dosing strategies for antimicrobial therapy.

Research Area
Bacteria
Drug discovery and development
Drug resistance
Discipline
Bacteriology
Cell biology
Epidemiology
Medicine
Microbiology
Molecular biology
Virology
Disease and Health Conditions
Infectious disease
Tuberculosis
Respiratory disease
Coronavirus