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Professor Umberto Dalessandro

MD MSc PhD

Professor
Director of the MRC Unit The Gambia

Room
NA

MRC Unit The Gambia
Fajara
Gambia

Tel.
+2204495917

Prof. Umberto D'Alessandro (MD, MSc, PhD) has a long working experience in Africa, first as a clinician (Benin and Kenya) and later as a clinical epidemiologist (The Gambia). He has been involved in malaria research since 1990 when he carried out the evaluation of the Gambian National programme on insecticide-treated bed nets. He joined the Department of Parasitology at the Institute of Tropical Medicine, Antwerp, Belgium in 1996 where he was, until the end of 2010, was the head of the Epidemiology Unit. There, he developed a research program around three themes: antimalarial treatment, including drug resistance, malaria prevention, and the P. vivax in vitro cycle, implemented in several malaria endemic countries, e.g. Uganda, Burkina Faso, Benin, Vietnam, Peru, etc.

 

In 2011, Professor D’Alessandro joined the Medical Research Council Unit The Gambia (MRCG) as theme leader of disease control and elimination. In January 2014, he was appointed director of the MRCG. His research program on malaria at the MRCG is built around questions related to malaria elimination/eradication.

Affiliations

Faculty of Infectious and Tropical Diseases
Department of Disease Control

Centres

Malaria Centre

Teaching

Prof D'Alessandro has supervised 22 PhD students. He is currently supervising 3 PhD students. 

Recently completed doctoral students:

Francois Noulin (France) - " Production of stem cell-derived reticulocytes for the in-vitro culture of Plasmodium vivax blood cycle. Leuven University, Faculty of Medicine, 2014.

Christine Manyando (Zambia) - "Options for Treatment and Control of Malaria in Pregnancy in Zambia." University of Antwerp, Faculty of Medical Sciences, 2014. 

Eniyou Oriero (Nigeria) -"Field implementation and evaluation of novel isothermal, nucleic acid -based diagnostic tools for malaria elimination in sub-Saharan Africa. University of Antwerp, Faculty of Medical Sciences, October 2015.

Daniel Kajungu (Uganda) - "Data mining methods for pharmacovigilance in Africa. Catholic University of Leuven, December 2015. 

Kevind Opondo (Kenya)- "Roles of biting preference and insecticide resistance in determining malaria transmission heterogeneity in The Gambia". University of Liverpool, June 2016. 

Marc Tahita (Burkina Faso) - "Case management and control of Malaria in Pregnancy: Case of Burkina Faso". University of Antwerp, Faculty of Medical Sciences, May 2017.

Joseph Okebe (Nigeria)- "Identifying residual foci of malaria infection in a context of decreasing transmission. From control to elimination: reducing residual malaria transmission in The Gambia". Faculty of Medical Sciences, May 2017.

Current PhD candidates: 

Michael Nambozi (Zambia) -" Antimalarial treatment efficacy and safet in pregnant women."

Expected completion: 2019

Julia Mwesigwa (Uganda) - "Malaria residual transmission and mass drug administration in The Gambia."

Expected completion: Spring 2020

Abdullahi Ahmad (Nigeria) - "The importance of asymptomatic malaria carriers in maintaining transmission"

Expected completion: 2022

 

Research

Research Area
Child health
Clinical care
Clinical trials
Diagnostics
Drug resistance
Maternal health
Parasites
Perinatal health
Public health
Chemotherapy
Disease control
Global Health
Medicines
Neonatal health
Randomised controlled trials
Discipline
Genetic epidemiology
Immunoepidemiology
Molecular epidemiology
Demography
Epidemiology
Medicine
Parasitology
Entomology
Disease and Health Conditions
Cardiovascular disease
Infectious disease
Malaria
Hepatitis
Sepsis
Country
Benin
Burkina Faso
Guinea
The Gambia
Mali
Senegal
Region
Sub-Saharan Africa (developing only)

Selected Publications

Impact of intrapartum oral azithromycin on the acquired macrolide resistome of infants' nasopharynx: a randomised controlled trial.
Bojang A; Baines SL; Camara B; Guerillot R; Donovan L; Marqués RS; Secka O; D'Alessandro U; Bottomley C; Howden BP
2020
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
PRECISE pregnancy cohort: challenges and strategies in setting up a biorepository in sub-Saharan Africa
Craik R; Russell D; Tribe RM; Poston L; Omuse G; Okiro P; Chege D; Diatta M; Sesay AK; Cuamba I
2020
Reproductive Health
The contribution of qualitative research within the PRECISE study in sub-Saharan Africa.
Daniele MAS; Martinez-Alvarez M; Etyang AK; Vidler M; Salisbury T; Makanga PT; Musitia P; Flint-O'Kane M; Brown TW; Diallo BA
2020
Reproductive health
Harnessing the PRECISE network as a platform to strengthen global capacity for maternal and child health research in sub-Saharan Africa.
Flint-O'Kane M; von Dadelszen P; Makanga PT; Sevene E; Roca A; Dukes P; Hinrichs-Krapels S; Craik R; Magee LA; Temmerman M
2020
Reproductive health
The PRECISE (PREgnancy Care Integrating translational Science, Everywhere) database: open-access data collection in maternal and newborn health.
Magee LA; Strang A; Li L; Tu D; Tumtaweetikul W; Craik R; Daniele M; Etyang AK; D'Alessandro U; Ogochukwu O
2020
Reproductive health
The PRECISE (PREgnancy Care Integrating translational Science, Everywhere) Network's first protocol: deep phenotyping in three sub-Saharan African countries.
von Dadelszen P; Flint-O'Kane M; Poston L; Craik R; Russell D; Tribe RM; d'Alessandro U; Roca A; Jah H; Temmerman M
2020
Reproductive health
Optimisation and standardisation of a multiplex immunoassay of diverse Plasmodium falciparum antigens to assess changes in malaria transmission using sero-epidemiology.
Wu L; Hall T; Ssewanyana I; Oulton T; Patterson C; Vasileva H; Singh S; Affara M; Mwesigwa J; Correa S
2020
Wellcome open research
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