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Professor Taane Clark

DPhil

Professor
of Genomics and Global Health

Room
K392

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Tel.
+44 (0)20 7927 2484

Taane has expertise in biostatistics, statistical and population genetics, and genomic epidemiology.

Affiliations

Faculty of Infectious and Tropical Diseases
Faculty of Epidemiology and Population Health
Department of Infection Biology

Teaching

Infectious disease 'omics, Genomic epidemiology

Research

His main research interests include the design and analysis of large-scale association studies of infectious diseases in humans, and the investigation of genetic variation in pathogen populations using high-throughput sequencing and genotyping technologies. He is leading global genetic diversity projects of Mycobacterium tuberculosis and Plasmodium species, as well as developing statistical and informatic tools to integrate genetic and important phenotypic information and identify genetic regions associated with important disease phenotypes (e.g. drug resistance). He organises short courses in Infectious Disease 'omics and Genomic epidemiology. Further details can be found at pathogenseq.lshtm.ac.uk

Research Area
Bacteria
Drug resistance
Human genetics
Parasites
Public health
Statistical methods
Viruses
Capacity strengthening
Global Health
Vector control
Discipline
Genetic epidemiology
Genomics
Molecular epidemiology
Epidemiology
Genetics
Statistics
Bioinformatics
Disease and Health Conditions
Diarrhoeal diseases
Infectious disease
Malaria
Pandemic diseases
Tuberculosis
Chronic Fatigue Syndrome
Emerging Infectious Disease
Non-communicable diseases
Respiratory disease
Vector borne disease
Zoonotic disease
Zika
Region
East Asia & Pacific (all income levels)
South Asia
Sub-Saharan Africa (all income levels)
World

Selected Publications

PowerBacGWAS: a computational pipeline to perform power calculations for bacterial genome-wide association studies.
Coll F; Gouliouris T; Bruchmann S; Phelan J; Raven KE; Clark TG; Parkhill J; Peacock SJ
2022
Communications biology
A phylogenomic approach for the analysis of colistin resistance-associated genes in Klebsiella pneumoniae, its mutational diversity and implications for phenotypic resistance.
Elias R; Spadar A; Phelan J; Melo-Cristino J; Lito L; Pinto M; Gonçalves L; Campino S; Clark TG; Duarte A
2022
International journal of antimicrobial agents
Molecular characterization of drug-resistant Mycobacterium tuberculosis among Filipino patients derived from the national tuberculosis prevalence survey Philippines 2016.
Montoya JC; Malabad JCM; Ang CF; Reyes LT; Basilio RP; Lim DR; Amarillo MLE; Ama MCG; Phelan JE; Hibberd ML
2022
Tuberculosis (Edinburgh, Scotland)
Characterisation of drug-resistant Mycobacterium tuberculosis mutations and transmission in Pakistan.
Napier G; Khan AS; Jabbar A; Khan MT; Ali S; Qasim M; Mohammad N; Hasan R; Hasan Z; Campino S
2022
Scientific reports
COVID-profiler: a webserver for the analysis of SARS-CoV-2 sequencing data.
Phelan J; Deelder W; Ward D; Campino S; Hibberd ML; Clark TG
2022
BMC Bioinformatics
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