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Professor Taane Clark

DPhil

Professor
of Genomics and Global Health

Room
K284

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Tel.
+44 (0)20 7927 2484

Taane has expertise in biostatistics, statistical and population genetics, and genomic epidemiology

Affiliations

Faculty of Infectious and Tropical Diseases
Department of Infection Biology
Faculty of Epidemiology and Population Health
Department of Infectious Disease Epidemiology

Centres

Malaria Centre
Mathematical Modelling of Infectious Diseases
Statistical Methodology
Tuberculosis (TB) Centre

Teaching

Pathogen genomics, Genetic epidemiology

Research

His main research interests include the design and analysis of large-scale association studies of infectious diseases in humans, and the investigation of genetic variation in pathogen populations using high-throughput sequencing and genotyping technologies. He is leading global genetic diversity projects of Mycobacterium tuberculosis and Plasmodium species, as well as developing statistical and informatic tools to integrate genetic and important phenotypic information and identify genetic regions associated with important disease phenotypes (e.g. drug resistance). He organises short courses in Pathogen genomics and Genetic epidemiology. Further details can be found at pathogenseq.lshtm.ac.uk

Research Area
Bacteria
Drug resistance
Human genetics
Parasites
Public health history
Statistical methods
Global Health
Discipline
Genetic epidemiology
Genomics
Molecular epidemiology
Epidemiology
Genetics
Statistics
Bioinformatics
Disease and Health Conditions
Infectious disease
Malaria
Tuberculosis
Non-communicable diseases
Region
World

Selected Publications

Whole genome sequencing of amplified Plasmodium knowlesi DNA from unprocessed blood reveals genetic exchange events between Malaysian Peninsular and Borneo subpopulations.
Benavente ED; Gomes AR; De Silva JR; Grigg M; Walker H; Barber BE; William T; Yeo TW; de Sessions PF; Ramaprasad A
2019
Scientific reports
Rapid and iterative genome editing in the malaria parasite Plasmodium knowlesi provides new tools for P. vivax research.
Mohring F; Hart MN; Rawlinson TA; Henrici R; Charleston JA; Diez Benavente E; Patel A; Hall J; Almond N; Campino S
2019
eLife
Mycobacterium tuberculosis whole genome sequencing provides insights into the Manila strain and drug-resistance mutations in the Philippines.
Phelan JE; Lim DR; Mitarai S; de Sessions PF; Tujan MAA; Reyes LT; Medado IAP; Palparan AG; Naim ANM; Jie S
2019
Scientific reports
Association of Malaria Infection During Pregnancy With Head Circumference of Newborns in the Brazilian Amazon.
Dombrowski JG; Souza RMD; Lima FA; Bandeira CL; Murillo O; Costa DDS; Peixoto EPM; Cunha MDP; Zanotto PMDA; Bevilacqua E
2019
JAMA network open
A novel Ancestral Beijing sublineage of Mycobacterium tuberculosis suggests the transition site to Modern Beijing sublineages.
Ajawatanawong P; Yanai H; Smittipat N; Disratthakit A; Yamada N; Miyahara R; Nedsuwan S; Imasanguan W; Kantipong P; Chaiyasirinroje B
2019
Scientific reports
Integrating informatics tools and portable sequencing technology for rapid detection of resistance to anti-tuberculous drugs.
Phelan JE; O'Sullivan DM; Machado D; Ramos J; Oppong YEA; Campino S; O'Grady J; McNerney R; Hibberd ML; Viveiros M
2019
Genome medicine
Whole genome sequencing of drug resistant Mycobacterium tuberculosis isolates from a high burden tuberculosis region of North West Pakistan.
Jabbar A; Phelan JE; de Sessions PF; Khan TA; Rahman H; Khan SN; Cantillon DM; Wildner LM; Ali S; Campino S
2019
Scientific reports
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