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Prof Taane Clark

Professor of Genomics and Global Health

United Kingdom

Taane has expertise in biostatistics, statistical and population genetics, and genomic epidemiology.

Affiliations

Department of Infection Biology
Faculty of Infectious and Tropical Diseases

Centres

Malaria Centre
Centre for Mathematical Modelling of Infectious Diseases
TB Centre
Antimicrobial Resistance Centre

Research

His main research interests include the design and analysis of large-scale association studies of infectious diseases in humans, and the investigation of genetic variation in pathogen populations using high-throughput sequencing and genotyping technologies. He is leading global genetic diversity projects of Mycobacterium tuberculosis and Plasmodium species, as well as developing statistical and informatic tools to integrate genetic and important phenotypic information and identify genetic regions associated with important disease phenotypes (e.g. drug resistance). He organises short courses in Infectious Disease 'omics and Genomic epidemiology.
Research Area
Bacteria
Drug resistance
Global Health
Human genetics
Outbreaks
Parasites
Vector control
Bioinformatics
Genetic Epidemiology
Genomics
Disease and Health Conditions
Diarrhoeal diseases
Malaria
Tuberculosis
Infectious diseases
Vector borne diseases
Region
World

Selected Publications

Exploring optimal drug targets through subtractive proteomics analysis and pangenomic insights for tailored drug design in tuberculosis.
Khan, MF; Ali, A; Rehman, HM; Noor Khan, S; Hammad, HM; Waseem, M; Wu, Y; CLARK, TG; Jabbar, A;
2024
Scientific reports
A new method for detecting mixed<i>Mycobacterium tuberculosis</i>infection and reconstructing constituent strains provides insights into transmission
Sobkowiak, B; Cudahy, P; Chitwood, MH; CLARK, TG; Colijn, C; Grandjean, L; Walter, KS; Crudu, V; Cohen, T;
2024
Cold Spring Harbor Laboratory
Genome-wide association study of global Plasmodium vivax populations provides insights into the evolution of drug resistance
Ngwana-Joseph, G; PHELAN, J; Manko, E; Dombrowski, J; Santos, SD; Suarez-Mutis, M; Machado, RL; Marinho, C; Nolder, D; Nosten, F; SUTHERLAND, C; CAMPINO, S; CLARK, T;
2024
Research Square
Diversity, functional classification and genotyping of SHV β-lactamases in<i>Klebsiella pneumoniae</i>
Tsang, K; Lam, MM C; Wick, R; Wyres, K; Bachman, M; Baker, S; Barry, K; Brisse, S; Campino, S; Chiaverini, A; Cirillo, DM; CLARK, T; Corander, J; Corbella, M; Cornacchia, A; Cuénod, A; D’Alterio, N; Di Marco, F; Donado-Godoy, P; Egli, A; Farzana, R; Feil, E; Fostervold, A; Gorrie, C; Gütlin, Y; ... KlebNET AMR Genotype-Phenotype Group,
2024
bioRxiv
Multi-platform whole genome sequencing for tuberculosis clinical and surveillance applications.
Thorpe, J; Sawaengdee, W; Ward, D; Campos, M; Wichukchinda, N; Chaiyasirinroje, B; Thanraka, A; Chumpol, J; PHELAN, JE; CAMPINO, S; Mahasirimongkol, S; CLARK, TG;
2024
Scientific reports
Newly Identified Mycobacterium africanum Lineage 10, Central Africa.
Guyeux, C; Senelle, G; Le Meur, A; Supply, P; Gaudin, C; PHELAN, JE; CLARK, TG; Rigouts, L; De Jong, B; Sola, C; Refrégier, G;
2024
Emerging infectious diseases
Profiling insecticide resistance phenotypes and genotypes in Aedes aegypti populations across four regions in Puerto Rico
Collins, E; Quintana, JM; Morales, R; Moss, S; Acford-Palmer, H; Higgins, M; Phelan, J; CLARK, T; Brown, G; Campino, S;
2024
Research Square
New reference genomes to distinguish the sympatric malaria parasites, Plasmodium ovale curtisi and Plasmodium ovale wallikeri.
Higgins, M; Manko, E; Ward, D; PHELAN, JE; Nolder, D; SUTHERLAND, CJ; CLARK, TG; CAMPINO, S;
2024
Scientific reports
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