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Professor Taane Clark

DPhil

Professor
of Genomics and Global Health

Room
K284

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Tel.
+44 (0)20 7927 2484

Taane has expertise in biostatistics, statistical and population genetics, and genomic epidemiology

Affiliations

Department of Infectious Disease Epidemiology
Faculty of Infectious and Tropical Diseases
Faculty of Epidemiology and Population Health
Department of Infection Biology

Centres

Malaria Centre
Mathematical Modelling of Infectious Diseases
Statistical Methodology
Tuberculosis (TB) Centre

Teaching

Pathogen genomics, Genetic epidemiology

Research

His main research interests include the design and analysis of large-scale association studies of infectious diseases in humans, and the investigation of genetic variation in pathogen populations using high-throughput sequencing and genotyping technologies. He is leading global genetic diversity projects of Mycobacterium tuberculosis and Plasmodium species, as well as developing statistical and informatic tools to integrate genetic and important phenotypic information and identify genetic regions associated with important disease phenotypes (e.g. drug resistance). He organises short courses in Pathogen genomics and Genetic epidemiology. Further details can be found at pathogenseq.lshtm.ac.uk

Research Area
Bacteria
Drug resistance
Human genetics
Parasites
Public health history
Statistical methods
Global Health
Discipline
Genetic epidemiology
Genomics
Molecular epidemiology
Epidemiology
Genetics
Statistics
Bioinformatics
Disease and Health Conditions
Infectious disease
Malaria
Tuberculosis
Non-communicable diseases
Region
World

Selected Publications

A molecular barcode to inform the geographical origin and transmission dynamics of Plasmodium vivax malaria.
Diez Benavente E; Campos M; Phelan J; Nolder D; Dombrowski JG; Marinho CRF; Sriprawat K; Taylor AR; Watson J; Roper C
2020
PLoS genetics
Discordant bioinformatic predictions of antimicrobial resistance from whole-genome sequencing data of bacterial isolates: an inter-laboratory study.
Doyle RM; O'Sullivan DM; Aller SD; Bruchmann S; Clark T; Coello Pelegrin A; Cormican M; Diez Benavente E; Ellington MJ; McGrath E
2020
Microbial Genomics
The Lancet Respiratory Medicine Commission: 2019 update: epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant and incurable tuberculosis.
Dheda K; Gumbo T; Maartens G; Dooley KE; Murray M; Furin J; Nardell EA; Warren RM; Lancet Respiratory Medicine drug-resistant tuberculosis Commission group
2019
The Lancet. Respiratory medicine
Whole genome sequencing of drug resistant Mycobacterium tuberculosis isolates from a high burden tuberculosis region of North West Pakistan.
Jabbar A; Phelan JE; de Sessions PF; Khan TA; Rahman H; Khan SN; Cantillon DM; Wildner LM; Ali S; Campino S
2019
Scientific reports
Whole genome sequencing of amplified Plasmodium knowlesi DNA from unprocessed blood reveals genetic exchange events between Malaysian Peninsular and Borneo subpopulations.
Benavente ED; Gomes AR; De Silva JR; Grigg M; Walker H; Barber BE; William T; Yeo TW; de Sessions PF; Ramaprasad A
2019
Scientific reports
A comprehensive analysis of drug resistance molecular markers and Plasmodium falciparum genetic diversity in two malaria endemic sites in Mali.
Diakité SAS; Traoré K; Sanogo I; Clark TG; Campino S; Sangaré M; Dabitao D; Dara A; Konaté DS; Doucouré F
2019
Malaria journal
Machine Learning Predicts Accurately Mycobacterium tuberculosis Drug Resistance From Whole Genome Sequencing Data.
Deelder W; Christakoudi S; Phelan J; Benavente ED; Campino S; McNerney R; Palla L; Clark TG
2019
Frontiers in Genetics
A novel Ancestral Beijing sublineage of Mycobacterium tuberculosis suggests the transition site to Modern Beijing sublineages.
Ajawatanawong P; Yanai H; Smittipat N; Disratthakit A; Yamada N; Miyahara R; Nedsuwan S; Imasanguan W; Kantipong P; Chaiyasirinroje B
2019
Scientific reports
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