Close

Professor Graham Clark

BSc PhD

Professor
in Molecular Parasitology

Room
Room K/329b

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Tel.
44 20 7927 2351

I joined the Faculty in 1996, after obtaining a BSc (Hons) in Zoology from the University of Edinburgh, a PhD from the Rockefeller University in New York, and postdoctoral training at the U.S. National Institutes of Health in Bethesda, Maryland. (Full CV)

Affiliations

Department of Infection Biology
Division of Education
Faculty of Infectious and Tropical Diseases

Teaching

I teach molecular biology methods and lecture on gut protozoa. Following 10 years as a Programme Director, from August 2009 until September 2016 I was Taught Programme Director for the Faculty of Infectious and Tropical Diseases, which meant I had oversight of teaching on all the MScs, Short Courses and modules run by the Faculty. In February 2014 I became Associate Dean of Education with responsibility for Quality, Academic Standards and Collaborative Provision across the School, and I am a member of several School-level education committees.

Research

My main interests are in the genetic diversity and evolution of gut protozoan parasites, especially Entamoeba histolytica, the agent responsible for amoebic dysentery and amoebic liver abscesses, other species of Entamoeba, and Blastocystis, an organism of uncertain pathogenicity. I was involved in the E. histolytica genome project and I run the Entamoeba Homepage. The work on Blastocystis has focussed on the link between host range and genetic variation, as well as attempting to understand the function of the mitochondrial organelle in this anaerobic organism. Genome sequencing of Blastocystis and its relative Proteromonas - both mitochondrial and nuclear - has been undertaken. My ORCID ID is 0000-0002-0521-0977

Research Area
Parasites
Protozoa
Discipline
Genomics
Molecular epidemiology
Parasitology
Disease and Health Conditions
Diarrhoeal diseases
Emerging Infectious Disease
Region
World

Selected Publications

Pre-empting Pandora's Box: Blastocystis Subtypes Revisited.
Stensvold CR; Clark CG
2020
Trends in Parasitology
Differentiation of Blastocystis and parasitic archamoebids encountered in untreated wastewater samples by amplicon-based next-generation sequencing.
Stensvold CR; Lebbad M; Hansen A; Beser J; Belkessa S; O'Brien Andersen L; Clark CG
2019
Parasite Epidemiology and Control
Genetic Diversity and Gene Family Expansions in Members of the Genus Entamoeba.
Wilson IW; Weedall GD; Lorenzi H; Howcroft T; Hon C-C; Deloger M; Guillén N; Paterson S; Clark CG; Hall N
2019
Genome Biology and Evolution
Novel Entamoeba Findings in Nonhuman Primates.
Elsheikha HM; Regan CS; Clark CG
2018
Trends in parasitology
Extreme genome diversity in the hyper-prevalent parasitic eukaryote Blastocystis.
Gentekaki E; Curtis BA; Stairs CW; Klimeš V; Eliáš M; Salas-Leiva DE; Herman EK; Eme L; Arias MC; Henrissat B
2017
PLoS biology
Blastocystis Mitochondrial Genomes Appear to Show Multiple Independent Gains and Losses of Start and Stop Codons.
Jacob AS; Andersen LO; Bitar PP; Richards VP; Shah S; Stanhope MJ; Stensvold CR; Clark CG
2016
Genome biology and evolution
Expanding the Entamoeba Universe: New Hosts Yield Novel Ribosomal Lineages.
Jacob AS; Busby EJ; Levy AD; Komm N; Clark CG
2015
The Journal of eukaryotic microbiology
Variable geographic distribution of Blastocystis subtypes and its potential implications.
Alfellani MA; Stensvold CR; Vidal-Lapiedra A; Onuoha ESU; Fagbenro-Beyioku AF; Clark CG
2013
Acta tropica
Genetic diversity of blastocystis in livestock and zoo animals.
Alfellani MA; Taner-Mulla D; Jacob AS; Imeede CA; Yoshikawa H; Stensvold CR; Clark CG
2013
Protist
See more Publications