Close

Professor Graham Clark

BSc PhD

Professor
in Molecular Parasitology

Room
Room K/329b

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Tel.
44 20 7927 2351

Fax.
44 20 7636 8739

I joined the Department in 1996, after obtaining a BSc (Hons) in Zoology from the University of Edinburgh, a PhD from the Rockefeller University in New York, and postdoctoral training at the U.S. National Institutes of Health in Bethesda, Maryland. (Full CV)

Affiliations

Department of Infection Biology
Division of Education
Faculty of Infectious and Tropical Diseases

Teaching

I teach molecular biology methods, lecture on gut protozoa, and contribute to phylogenetics teaching as part of various modules. I am also a Tutor on the Parasitology module of MSc in Infectious Diseases by Distance Learning. Following 10 years as a Programme Director, from August 2009 until September 2016 I was Taught Programme Director for the Faculty of Infectious and Tropical Diseases, which meant I had oversight of teaching on all the MScs, Short Courses and modules run by the Faculty. In February 2014 I became Associate Dean of Education with responsibility for Quality, Academic Standards and Collaborative Provision across the School.

Research

My main interests are in the genetic diversity and evolution of gut protozoan parasites, especially Entamoeba histolytica, the agent responsible for amoebic dysentery and amoebic liver abscesses, other species of Entamoeba, and Blastocystis, an organism of uncertain pathogenicity. I was involved in the E. histolytica genome project and I run the Entamoeba Homepage. The work on Blastocystis has focussed on its mitochondrial genome in an attempt to understand the function of the organelle in this anaerobic organism. Genome sequencing of Blastocystis and its relative Proteromonas - both mitochondrial and nuclear - is being undertaken at present. Genetic diversity within and between species is being explored in both Entamoeba and Blastocystis. My ORCID ID is 0000-0002-0521-0977

Research Area
Parasites
Protozoa
Discipline
Genomics
Molecular epidemiology
Molecular biology
Parasitology
Disease and Health Conditions
Diarrhoeal diseases
Emerging Infectious Disease
Neglected Tropical Diseases (NTDs)
Country
Bangladesh
United Kingdom
India
Libya
Region
World

Selected Publications

Genetic diversity and gene family expansions in members of the genus Entamoeba
Wilson IW; Weedall GD; Lorenzi H; Howcroft T; Hon C-C; Deloger M; Guillén N; Paterson S; Clark CG; Hall N
2019
Genome Biology and Evolution
Novel Entamoeba Findings in Nonhuman Primates.
Elsheikha HM; Regan CS; Clark CG
2018
Trends in parasitology
Extreme genome diversity in the hyper-prevalent parasitic eukaryote Blastocystis.
Gentekaki E; Curtis BA; Stairs CW; Klimeš V; Eliáš M; Salas-Leiva DE; Herman EK; Eme L; Arias MC; Henrissat B
2017
PLoS biology
Blastocystis mitochondrial genomes appear to show multiple independent gains and losses of start and stop codons.
Jacob AS; Andersen LO; Bitar PP; Richards VP; Shah S; Stanhope MJ; Stensvold CR; Clark CG
2016
Genome biology and evolution
Expanding the Entamoeba Universe: New Hosts Yield Novel Ribosomal Lineages.
Jacob AS; Busby EJ; Levy AD; Komm N; Clark CG
2015
The Journal of eukaryotic microbiology
Variable geographic distribution of Blastocystis subtypes and its potential implications.
Alfellani MA; Stensvold CR; Vidal-Lapiedra A; Onuoha ES; Fagbenro-Beyioku AF; Clark CG
2013
Acta tropica
Genetic Diversity of Blastocystis in Livestock and Zoo Animals.
Alfellani MA; Taner-Mulla D; Jacob AS; Imeede CA; Yoshikawa H; Stensvold CR; Clark CG
2013
Protist
See more Publications