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Professor Matthew Burton

PhD MA MBBCh DTM&H MRCP FRCOphth

Professor
of International Eye Health & Wellcome Trust Senior Research Fellow in Clinical Science

Room
Room 394

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Tel.
+44 (0)20 7927 2329

Matthew Burton is an ophthalmologist. He qualified in medicine from Cambridge University in 1994. His post-graduate training was in Oxford and at Moorfields Eye Hospital, London. From 2001 to 2004 he worked as a clinical research fellow at the LSHTM on a Wellcome Trust funded trachoma research programme based at the MRC Laboratories in The Gambia. He was subsequently based at the Department of Ophthalmology, KCMC Hospital, Moshi, Tanzania from 2008 to 2012.

He is a Professor within the International Centre for Eye Health at the LSHTM and an Honorary Consultant Ophthalmologist at Moorfields Eye Hospital. Matthew holds a Wellcome Trust Senior Research Fellowship in Clinical Science and is Director of the Commonwealth Eye Health Consortium.

Affiliations

Department of Clinical Research
Faculty of Infectious and Tropical Diseases

Teaching

Matthew teaches on the MSc in Community Eye Health and the Tropical Ophthalmology Short Course in London and the East African DTM&H in Moshi.

Research

Matthew's main research focus is blinding eye infections. This has involved a range of projects on the control and pathogenesis of trachoma in Ethiopia, Tanzania and The Gambia. Studies have included several clinical trials on the management of trichiasis, longitudinal studies on the impact of mass azithromycin treatment and a range of studies investigating the immunopathogenic response that leads to the scarring complications of this infection. He leads a collaborative programme of trachoma research in Ethiopia called Stronger-SAFE which is seeking to understand the routes and dertminants of transmission, develop interventions to target these routes and to test them in a cluster randomised trial. 

Matthew also leads a research programme on fungals and bacterial corneal infections (microbial keratitis) in Uganda, Tanzania and Nepal. This is investigating intervention strategies to reduce the vision loss from this disease.

Research Area
Bacteria
Clinical trials
Complex interventions
Disease control
Global Health
Discipline
Immunopathology
Epidemiology
Immunology
Opthalmology
Disease and Health Conditions
Eye diseases
Infectious disease
Trachoma
Neglected Tropical Diseases (NTDs)
Country
Ethiopia
Gambia, The
India
Kenya
Nepal
Tanzania
Uganda
Region
South Asia
Sub-Saharan Africa (developing only)

Selected Publications

Posterior lamellar versus bilamellar tarsal rotation surgery for trachomatous trichiasis in Ethiopia: a randomised controlled trial.
Habtamu, E.; Wondie, T.; Aweke, S.; Tadesse, Z.; Zerihun, M.; Zewudie, Z.; Kello, A.B.; Roberts, C.H.; Emerson, P.M.; Bailey, R.L.; Mabey, D.C.; Rajak, S.N.; Callahan, K.; Weiss, H.A.; Burton, M.J.;
2016
Lancet Glob Health
Topical fluorouracil after surgery for ocular surface squamous neoplasia in Kenya: a randomised, double-blind, placebo-controlled trial.
Gichuhi, S. ; Macharia, E. ; Kabiru, J. ; Zindamoyen, A.M. ; Rono, H. ; Ollando, E. ; Wachira, J. ; Munene, R. ; Maina, J. ; Onyuma, T. ; Sagoo, M.S. ; Weiss, H.A. ; Burton, M.J. ;
2016
Lancet Glob Health
Development and Validation of a Smartphone-Based Visual Acuity Test (Peek Acuity) for Clinical Practice and Community-Based Fieldwork.
Bastawrous, A.; Rono, H.K.; Livingstone, I.A.; Weiss, H.A.; Jordan, S.; Kuper, H.; Burton, M.J.;
2015
JAMA Ophthalmol
Surgery versus epilation for the treatment of minor trichiasis in ethiopia: a randomised controlled noninferiority trial.
Rajak, S.N. ; Habtamu, E. ; Weiss, H.A. ; Kello, A.B. ; Gebre, T. ; Genet, A. ; Bailey, R.L. ; Mabey, D.C. ; Khaw, P.T. ; Gilbert, C.E. ; Emerson, P.M. ; Burton, M.J. ;
2011
PLoS Med
Absorbable versus silk sutures for surgical treatment of trachomatous trichiasis in ethiopia: a randomised controlled trial.
Rajak, S.N. ; Habtamu, E. ; Weiss, H.A. ; Kello, A.B. ; Gebre, T. ; Genet, A. ; Bailey, R.L. ; Mabey, D.C. ; Khaw, P.T. ; Gilbert, C.E. ; Emerson, P.M. ; Burton, M.J. ;
2011
PLoS Med
The conjunctival transcriptome in scarring trachoma.
Burton, M.J.; Rajak, S.N.; Bauer, J.; Weiss, H.A.; Tolbert, S.B.; Shoo, A.; Habtamu, E.; Manjurano, A.; Emerson, P.M.; Mabey, D.C.; Holland, M.J.; Bailey, R.L.;
2010
Infect Immun
Re-emergence of Chlamydia trachomatis infection after mass antibiotic treatment of a trachoma-endemic Gambian community: a longitudinal study.
Burton, M.J.; Holland, M.J.; Makalo, P.; Aryee, E.A.; Alexander, N.D.; Sillah, A.; Faal, H.; West, S.K.; Foster, A.; Johnson, G.J.; Mabey, D.C.; Bailey, R.L.;
2005
Lancet
A randomised controlled trial of azithromycin following surgery for trachomatous trichiasis in the Gambia.
Burton, M.J.; Kinteh, F.; Jallow, O.; Sillah, A.; Bah, M.; Faye, M.; Aryee, E.A.; Ikumapayi, U.N.; Alexander, N.D.; Adegbola, R.A.; Faal, H.; Mabey, D.C.; Foster, A.; Johnson, G.J.; Bailey, R.L.;
2005
Br J Ophthalmol
See all Professor Matthew Burton's Publications