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Professor Krishnan Bhaskaran

MSc PhD

Professor
of Statistical Epidemiology and Sir Henry Dale Fellow

Room
Room 256

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Tel.
ext 2268

I graduated from Sheffield University with a BSc Hons in Mathematics in 1999 and took an MSc in Medical Statistics at Leicester University in 2000-2001. I worked for 6 years at the MRC Clinical Trials Unit, on a variety of HIV trials and observational studies, with an emphasis on HIV seroconverters (individuals with well estimated dates of HIV infection). In October 2010, on gaining my PhD at LSHTM for a project looking at environmental risk factors for heart disease, I joined the department as a lecturer, and later senior lecturer. I completed an National Institute for Health Research postdoctoral fellowship to study the effects of widely prescribed drugs on cancer risk (2012-2014). I was then awarded a Wellcome Trust/Royal Society Sir Henry Dale Fellowship followed by a Wellcome Senior Research Fellowship to study cardiovascular disease risks among people with a history of cancer (2015 to present).

Affiliations

Faculty of Epidemiology and Population Health
Department of Non-communicable Disease Epidemiology

Centres

Centre for Statistical Methodology

Teaching

I am joint Research Degrees Co-ordinator for the Department of Non-Communicable Diseases Epidemiology, and co-director of the Extended Epidemiology MSc module. I deliver several lectures and practical sessions on the MSc in Epidemiology. I teach on the Extended Epidemiology, and Advanced Statistical Methods for Epidemiology (ASME) MSc modules, and on the Advanced Course in Epidemiological Analysis (ACEA) and Practical Pharmacoepidemiology short courses. 

Research

My main areas of interest are cancer epidemiology and cancer survivorship, and I lead the Beyond Cancer research group (https://www.lshtm.ac.uk/research/centres-projects-groups/beyond-cancer).

I hold a Wellcome Trust/Royal Society Sir Henry Dale Fellowship for a programme of work looking at cardiovascular diseases among people with a history of cancer. I have also led work on mental health and quality of life among cancer survivors. I will extend these work streams in a Wellcome Senior Research Fellowship beginning in Spring 2021, which will include investigation of broader vascular outcomes, and the role of specific cancer treatments. 

I have an ongoing interest in pharmacoepidemiology, particularly in relation to cancer outcomes, and completed an NIHR fellowship programme in this area. I have also studied other predictors of cancer risk, notably body mass index.

Throughout my work I have been interested in the use of eHealth data and am part of a wider group at LSHTM working with large-scale routinely collected data such as the Clinical Practice Research Datalink (CPRD) primary care data. I am one of the statistical leads in the large OpenSAFELY project, an initiative set up at the start of the 2019 COVID-19 pandemic, and designed to use linked health data sources covering most of the population of England to answer key questions about this emerging disease.

Finally, I am interested in methodological questions that arise during research into real clinical problems; for example how best to tackle time-varying confounding by indication in diabetes epidemiology, and when/how to use matching in cohort studies.

Research Area
Statistical methods
Electronic health records
Medicines
Discipline
Pharmacoepidemiology
Epidemiology
Statistics
Disease and Health Conditions
Cancer
Diabetes
Obesity

Selected Publications

HIV infection and COVID-19 death: a population-based cohort analysis of UK primary care data and linked national death registrations within the OpenSAFELY platform.
Bhaskaran K; Rentsch CT; MacKenna B; Schultze A; Mehrkar A; Bates CJ; Eggo RM; Morton CE; Bacon SCJ; Inglesby P
2021
The lancet. HIV
Prevalence of COVID-19-related risk factors and risk of severe influenza outcomes in cancer survivors: A matched cohort study using linked English electronic health records data.
Carreira H; Strongman H; Peppa M; McDonald HI; Dos-Santos-Silva I; Stanway S; Smeeth L; Bhaskaran K
2020
EClinicalMedicine
Factors associated with COVID-19-related death using OpenSAFELY.
Williamson EJ; Walker AJ; Bhaskaran K; Bacon S; Bates C; Morton CE; Curtis HJ; Mehrkar A; Evans D; Inglesby P
2020
Nature
Eligibility and subsequent burden of cardiovascular disease of four strategies for blood pressure-lowering treatment: a retrospective cohort study.
Herrett E; Gadd S; Jackson R; Bhaskaran K; Williamson E; van Staa T; Sofat R; Timmis A; Smeeth L
2019
Lancet
Association of BMI with overall and cause-specific mortality: a population-based cohort study of 3·6 million adults in the UK.
Bhaskaran K; Dos-Santos-Silva I; Leon DA; Douglas IJ; Smeeth L
2018
The lancet. Diabetes & endocrinology
Associations Between Breast Cancer Survivorship and Adverse Mental Health Outcomes: A Systematic Review.
Carreira H; Williams R; Müller M; Harewood R; Stanway S; Bhaskaran K
2018
Journal of the National Cancer Institute
Long term adjuvant endocrine therapy and risk of cardiovascular disease in female breast cancer survivors: systematic review.
Matthews A; Stanway S; Farmer RE; Strongman H; Thomas S; Lyon AR; Smeeth L; Bhaskaran K
2018
BMJ (Clinical research ed)
Impact of statin related media coverage on use of statins: interrupted time series analysis with UK primary care data.
Matthews A; Herrett E; Gasparrini A; Van Staa T; Goldacre B; Smeeth L; Bhaskaran K
2016
BMJ (Clinical research ed)
Body-mass index and risk of 22 specific cancers: a population-based cohort study of 5·24 million UK adults.
Bhaskaran K; Douglas I; Forbes H; dos-Santos-Silva I; Leon DA; Smeeth L
2014
Lancet
Changes in the risk of death after HIV seroconversion compared with mortality in the general population.
Bhaskaran K; Hamouda O; Sannes M; Boufassa F; Johnson AM; Lambert PC; Porter K; CASCADE Collaboration
2008
JAMA
Determinants of survival following HIV-1 seroconversion after the introduction of HAART.
Porter K; Babiker A; Bhaskaran K; Darbyshire J; Pezzotti P; Porter K; Walker AS; CASCADE Collaboration
2003
Lancet
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