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Dr David Allen

BSc PhD FHEA

Associate Professor
of Virology

Room
360

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

I studied for my BSc in Virology and Immunology at the University of Warwick, then completed my PhD working jointly at the London School of Hygiene and Tropical Medicine and the Health Protection Agency (now Public Health England).

Following this, I worked with the Medical Research Council, and then returned to the Health Protection Agency/Public Health England, where I was Head of the National Enteric Virus Reference Unit.

I have worked with national and international public health agencies, including the World Health Organization, with the Global Polio Laboratory Network.

Affiliations

Department of Infection Biology
Faculty of Infectious and Tropical Diseases

Centres

Vaccine Centre

Teaching

I am involved in the MSc in Medical Microbiology, as Deputy Module Organiser and amd part of the Programme Committee for this MSc programme.

I am a Module Organiser, and teach on 3121 Core Virology, 3187 Clinical Virology, and 3140 Molecular Viology modules.

I am a tutor for the Infectious Diseases (Distance Learning) course module Viral Infections (DL).

I hold a Postgraduate Certificate in Learning & Teaching (PGCILT) and am a Fellow of the Higher Education Academy.

Research

My research interests are in human virus infections, and currently have active research projects on enteric virus infections such as norovirus, rotavirus and enterovirus, and emerging infections including SARS-CoV-2 and CCHFV.

These research programmes are focussed on the features of these viruses that drive their highly dynamic epidemiology, allowing them to emerge and persist in human populations, and understanding virus-host interactions and host responses to these viruses that influence the outcomes of infection. Additionally, my research group is interested in new approaches to diagnosis and surveillance of these viral infections.

I am a Member of the NIHR Health Protection Research Unit in Gastrointestinal Infections.

For more inforation on the team and our research, vist the Allen Laboratory webpage: www.allenlabvirology.com

Research Area
Diagnostics
Environment
Public health
Surveillance
Viruses
Disease control
Outbreaks
Discipline
Genomics
Molecular epidemiology
Molecular biology
Virology
Disease and Health Conditions
Diarrhoeal diseases
Infectious disease
Neurological disease
Pandemic diseases
Emerging Infectious Disease
Coronavirus
Country
Burkina Faso
United Kingdom
Ghana
Gambia
Kenya
Uganda
Region
Sub-Saharan Africa (all income levels)

Selected Publications

A high-resolution melt curve toolkit to identify lineage-defining SARS-CoV-2 mutations.
Fraser AJ; Greenland-Bews C; Kelly D; Williams CT; LSTM Diagnostics Group; CONDOR Steering Group; Body R; Adams ER; Atienzar AC; Edwards T
2023
Scientific reports
Emergent variant modeling of the serological repertoire to norovirus in young children.
Lindesmith LC; Brewer-Jensen PD; Conrad H; O'Reilly KM; Mallory ML; Kelly D; Williams R; Edmunds WJ; Allen DJ; Breuer J
2023
Cell Rep Med
Immune Imprinting Drives Human Norovirus Potential for Global Spread.
Lindesmith LC; Boshier FAT; Brewer-Jensen PD; Roy S; Costantini V; Mallory ML; Zweigart M; May SR; Conrad H; O'Reilly KM
2022
mBio
Surveillance optimisation to detect poliovirus in the pre-eradication era: a modelling study of England and Wales.
O'Reilly KM; Grassly NC; Allen DJ; Bannister-Tyrrell M; Cameron A; Carrion Martin AI; Ramsay M; Pebody R; Zambon M
2020
Epidemiology and Infection
Impact of rotavirus vaccination on rotavirus genotype distribution and diversity in England, September 2006 to August 2016.
Hungerford D; Allen DJ; Nawaz S; Collins S; Ladhani S; Vivancos R; Iturriza-Gómara M
2019
Eurosurveillance
Challenges of investigating a large food-borne norovirus outbreak across all branches of a restaurant group in the United Kingdom, October 2016.
Morgan M; Watts V; Allen D; Curtis D; Kirolos A; Macdonald N; Maslen E; Morgan D; Saei A; Sedgwick J
2019
Eurosurveillance
An interactive data visualisation application to investigate nosocomial transmission of infections.
Smith CM; Allen DJ; Nawaz S; Kozlakidis Z; Nastouli E; Hayward A; Ward KN
2019
Wellcome Open Research
Effectiveness of oral rotavirus vaccination in England against rotavirus-confirmed and all-cause acute gastroenteritis.
Walker JL; Andrews NJ; Atchison CJ; Collins S; Allen DJ; Ramsay ME; Ladhani SN; Thomas SL
2019
Vaccine: X
Comparing the Clinical Severity of Disease Caused by Enteroviruses and Human Parechoviruses in Neonates and Infants.
Black S; Bradley C; Lai FY; Shenoy S; Bandi S; Allen DJ; Tang JW
2018
The Pediatric infectious disease journal
Increased detection of human parechovirus infection in infants in England during 2016: epidemiology and clinical characteristics.
Ferreras Antolín L; Kadambari S; Braccio S; Tang JW-T; Xerry J; Allen DJ; Ladhani SN; Parechovirus Surveillance Network
2018
Archives of disease in childhood
Recommendations for enterovirus diagnostics and characterisation within and beyond Europe.
Harvala H; Broberg E; Benschop K; Berginc N; Ladhani S; Susi P; Christiansen C; McKenna J; Allen D; Makiello P
2018
Journal of clinical virology
Influence of Nonpolio Enteroviruses and the Bacterial Gut Microbiota on Oral Poliovirus Vaccine Response: A Study from South India.
Praharaj I; Parker EPK; Giri S; Allen DJ; Silas S; Revathi R; Kaliappan SP; John J; Prasad JH; Kampmann B
2018
The Journal of infectious diseases
Molecular surveillance of norovirus, 2005-16: an epidemiological analysis of data collected from the NoroNet network.
van Beek J; de Graaf M; Al-Hello H; Allen DJ; Ambert-Balay K; Botteldoorn N; Brytting M; Buesa J; Cabrerizo M; Chan M
2018
The Lancet infectious diseases
Methods for ascertaining norovirus disease burdens.
Allen DJ; Harris JP
2017
Human vaccines & immunotherapeutics
The emergence of enterovirus D68 in England in autumn 2014 and the necessity for reinforcing enterovirus respiratory screening.
Carrion Martin AI; Pebody RG; Danis K; Ellis J; Niazi S; DE Lusignan S; Brown KE; Zambon M; Allen DJ
2017
Epidemiology and infection
Isolation of Vaccine-Like Poliovirus Strains in Sewage Samples From the United Kingdom.
Majumdar M; Klapsa D; Wilton T; Akello J; Anscombe C; Allen D; Mee ET; Minor PD; Martin J
2017
The Journal of Infectious Diseases
An outbreak of norovirus GI-6 infection following a wedding in North West England.
Smith KC; Inns T; Decraene V; Fox A; Allen DJ; Shah A
2017
Epidemiology and infection
Antibodies against Lewis antigens inhibit the binding of human norovirus GII.4 virus-like particles to saliva but not to intestinal Caco-2 cells.
Carmona-Vicente N; Allen DJ; Rodríguez-Díaz J; Iturriza-Gómara M; Buesa J
2016
Virology journal
Characterization of a Novel Conformational GII.4 Norovirus Epitope: Implications for Norovirus-Host Interactions.
Carmona-Vicente N; Vila-Vicent S; Allen D; Gozalbo-Rovira R; Iturriza-Gómara M; Buesa J; Rodríguez-Díaz J
2016
Journal of virology
Emergence of the GII-4 Norovirus Sydney2012 strain in England, winter 2012-2013.
Allen DJ; Adams NL; Aladin F; Harris JP; Brown DWG
2014
PloS one
Molecular evolution of GII-4 Norovirus strains.
Zakikhany K; Allen DJ; Brown D; Iturriza-Gómara M
2012
PloS one
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