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Understanding diversity among Plasmodium falciparum isolates

Dr Sarah Tarr will deliver this talk entitled 'Understanding diversity among Plasmodium falciparum isolates through whole transcriptome analysis'.

Diversity in antigen expression levels captured through highly resolved whole-transcriptome profiling of clinical and laboratory-adapted malaria parasite isolates’.  In brief, we identify novel, variably-expressed merozoite antigens through whole transcriptome analysis of malaria parasite isolates using RNA-seq.  We validate our findings at the protein level, and at the transcriptomic level in a broader panel of clinical isolates.  These proteins constitute novel targets for characterisation for merozoite-stage intervention.

LSHTM is one of 61 institutions where strikes are set to take place over 14 days in response to an ongoing nationwide dispute on proposed changes to the USS pension scheme. Some events on strike days may be cancelled at short notice due to this. Please check the event listing before you travel. We appreciate your understanding and apologise for any inconvenience. 

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