A leprosy adventure: the Karonga research programme
This seminar will discuss leprosy and the history of leprosy research, including its relationship to the WHO TDR programme - which led to a major research programme in Karonga District in northern Malawi, associated with LSHTM, starting in 1979. Two total population surveys provided detailed descriptive and risk factor data, and a large RCT examined repeat BCG and a new vaccine containing killed M leprae. Long-term follow-up of the trial provided information on tuberculosis as well as leprosy. The project monitored a dramatic decline of leprosy and ultimately evolved into a broad-based national resource, the Malawi Epidemiology and Intervention Research Unit. This evolution may have implications for other research and control programmes.
Paul Fine, LSHTM
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