This module covers basic techniques in DNA manipulation including PCR amplification from genomic DNA, DNA cloning, plasmid preparation and DNA sequencing. It also includes sessions on bioinformatic analysis of DNA sequence data. The second component involves understanding and interpretation of scientific papers.

The overall module aim is to provide a basic understanding and practical experience of a range of reagents and methods that are the essential tools of the molecular biologist.

Intended learning outcomes

Upon successful completion of the module a student will be able to:

1. Demonstrate knowledge and understanding of the principles underpinning important techniques in molecular biology;
2. Demonstrate knowledge and understanding of some applications of these techniques in laboratory research on infectious diseases;
3. Demonstrate the ability to carry out laboratory experiments in molecular biology and bioinformatic analyses, and interpret the results;
4. Demonstrate the ability to read, comprehend and assess the relevant scientific literature.

Mode of delivery

This module is delivered predominantly face-to-face. Where specific teaching methods (lectures, seminars, discussion groups) are noted in this module specification these will be delivered by predominantly face-to-face sessions. There will be a combination of live and interactive activities (synchronous learning) as well as self-directed study (asynchronous learning).

Assessment

The assessment for this module has been designed to measure student learning against the module intended learning outcomes (ILOs) as listed above. The grade for summative assessment(s) only will go towards the overall award GPA.

The assessment(s) for this module will be online. There will be two components to the assessment:

1. Practical results (including bioinformatic analyses) will be written up (as answers to a specific set of questions, NOT in scientific paper format) and assessed to evaluate understanding of the practical portion.
2. A timed short answer written test will be held at the end of the module to evaluate scientific literature comprehension.

The grades for each component will be equally weighted and combined to give an overall GPA; written feedback is given on both.

Credits

• CATS: 15
• ECTS: 7.5

Module specification

For full information regarding this module please see the module specification.

Please note: information based on the 2024-25 module specification subject to change for 2025-26 entry.