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Dr Jiaxin Zhou

Research Fellow

United Kingdom

I am a Research Fellow at CMMID, LSHTM. My research integrates mathematical modelling with immunological, virological, and epidemiological data to explore how previous infections and vaccinations shape immune responses to influenza and SARS-CoV-2, and to investigate how antibody markers are associated with protection against infection. My previous work includes applying advanced statistical models in seroepidemiological studies of enterovirus, influenza, and measles among neonates, young children, and pregnant women; estimating the effectiveness of the EV-A71 monovalent vaccine; reconstructing the historical force of infection for multiple enteroviruses in China; characterising viral shedding patterns of SARS-CoV-2; and assessing the disease burden of COVID-19. I obtained my PhD in Epidemiology from Fudan University, China (2020-2024), and undertook an internship at Institut Pasteur, France (2023).

Affiliations

Department of Infectious Disease Epidemiology and Dynamics
Faculty of Epidemiology and Population Health

Teaching

  • Lead Instructor, ‘Serofoi’ R package training for postgraduate students and health professionals, Infectious Disease Modelling Workshop, KEMRI–Wellcome Trust, Kenya, Africa.
  • Teaching Assistant, Introduction to Infectious Disease Modelling (MSc course), London School of Hygiene & Tropical Medicine.

Research

My research interests focus on linking biomarker data with infectious disease dynamics to understand host-pathogen interactions, immune correlates of infection risk, and their implications for pandemic preparedness. Open to collaboration to advance research and create meaningful impact.
Research Area
Serology, vaccines
Immunity
Virology
Public health
Mathematical modelling
Applied statistics (medical)
Epidemiology
Bayesian analysis
Disease and Health Conditions
Influenza
Infectious diseases
Respiratory diseases
COVID-19

Selected Publications

Viral load dynamics in asymptomatic and symptomatic patients during Omicron BA.2 outbreak in Shanghai, China, 2022: A longitudinal cohort study
Ai, J; ZHOU, J; Li, Y; Sun, F; Ge, S; Zhang, H; Wu, Y; Wang, Y; Zhang, Y; Wang, H; Cai, J; Zhou, X; Wang, S; Li, R; Feng, Z; Xu, X; Yan, X; Zhao, Y; Zhang, J; Yu, H; Zhang, W;
2024
Virologica Sinica
Transplacental transfer efficiency of maternal antibodies against influenza A(H1N1)pdm09 virus and dynamics of naturally acquired antibodies in Chinese children: a longitudinal, paired mother-neonate cohort study.
Li, M; Wang, W; Chen, J; Zhan, Z; Xu, M; Liu, N; Ren, L; You, L; Zheng, W; Shi, H; Zhao, Z; Huang, C; Chen, X; Zheng, N; Lu, W; Zhou, X; ZHOU, J; Liao, Q; Yang, J; JIT, M; Salje, H; Yu, H;
2023
The Lancet microbe
The transfer of maternal antibodies and dynamics of maternal and natural infection-induced antibodies against coxsackievirus A16 in Chinese children 0-13 years of age: a longitudinal cohort study.
ZHOU, J; Zhou, Y; Luo, K; Liao, Q; Zheng, W; Gong, H; Shi, H; Zhao, S; Wang, K; Qiu, Q; Dai, B; Ren, L; Wang, L; Gao, L; Xu, M; Liu, N; Lu, W; Zheng, N; Chen, X; Chen, Z; Yang, J; Cauchemez, S; Yu, H;
2022
BMC Medicine
Comparison of Neutralizing Antibody Response Kinetics in Patients with Hand, Foot, and Mouth Disease Caused by Coxsackievirus A16 or Enterovirus A71: A Longitudinal Cohort Study of Chinese Children, 2017-2019.
Zhou, Y; ZHOU, J; Yang, J; Qiu, Q; Wang, L; Yang, J; Li, Y; Liang, L; Cui, P; Cheng, Y; Zheng, W; Shi, H; Gong, H; Wang, K; Zhou, C; Chu, JJ H; Yu, H;
2022
Journal of immunology (Baltimore, Md. : 1950)
Kinetics of the neutralising antibody response in patients with hand, foot, and mouth disease caused by EV-A71: A longitudinal cohort study in Zhengzhou during 2017-2019.
Qiu, Q; ZHOU, J; Cheng, Y; Zhou, Y; Liang, L; Cui, P; Xue, Y; Wang, L; Wang, K; Wang, H; Li, P; Chen, J; Li, Y; Turtle, L; Yu, H;
2021
EBioMedicine
The transfer and decay of maternal antibodies against enterovirus A71, and dynamics of antibodies due to later natural infections in Chinese infants: a longitudinal, paired mother-neonate cohort study.
Wei, X; Yang, J; Gao, L; Wang, L; Liao, Q; Qiu, Q; Luo, K; Yu, S; Zhou, Y; Liu, F; Chen, Q; Zhang, J; Dai, B; Yang, H; ZHOU, J; Xing, W; Chen, X; He, M; Ren, L; Guo, J; Luo, L; Wu, P; Chen, Z; Van Doorn, HR; Cauchemez, S; ... Yu, H.
2020
The Lancet. Infectious diseases
Case Fatality Risk of the First Pandemic Wave of Coronavirus Disease 2019 (COVID-19) in China.
Deng, X; Yang, J; Wang, W; Wang, X; ZHOU, J; Chen, Z; Li, J; Chen, Y; Yan, H; Zhang, J; Zhang, Y; Wang, Y; Qiu, Q; Gong, H; Wei, X; Wang, L; Sun, K; Wu, P; Ajelli, M; Cowling, BJ; Viboud, C; Yu, H;
2020
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Detection of Covid-19 in Children in Early January 2020 in Wuhan, China.
Liu, W; Zhang, Q; Chen, J; Xiang, R; Song, H; Shu, S; Chen, L; Liang, L; ZHOU, J; You, L; Wu, P; Wu, P; Zhang, B; Lu, Y; Xia, L; Huang, L; Yang, Y; Liu, F; Semple, MG; Cowling, BJ; Lan, K; Sun, Z; Yu, H; Liu, Y;
2020
The New England journal of medicine
Specificity, kinetics and longevity of antibody responses to avian influenza A(H7N9) virus infection in humans.
Chen, J; Zhu, H; Horby, PW; Wang, Q; ZHOU, J; Jiang, H; Liu, L; Zhang, T; Zhang, Y; Chen, X; Deng, X; Nikolay, B; Wang, W; Cauchemez, S; Guan, Y; Uyeki, TM; Yu, H;
2020
The Journal of infection
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